868359-05-1
WAY-213613(N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE)
CAS: 868359-05-1
化学式: C16H13BrF2N2O4
| 中文名 | WAY-213613 |
| 英文名 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE |
| 英文别名 | WAY-213613 N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE |
| CAS | 868359-05-1 |
| 化学式 | C16H13BrF2N2O4 |
| 分子量 | 415.19 |
| 溶解度 | 溶于DMSO |
| 存储条件 | -20℃ |
| 产品用途 | WAY-213613 is a potent, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). WAY-213613 exhibits no activity towards ionotropic and metabotropic glutamate receptors. |
| 靶点 | Human EAAT2 Human EAAT3 Human EAAT1 |
| 参考资料 展开查看 | 1: Karatas-Wulf U, Koepsell H, Bergert M, Sönnekes S, Kugler P. Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells. Neuroscience. 2009 Jul 7;161(3):794-805. doi: 10.1016/j.neuroscience.2009.04.017. Epub 2009 Apr 11. PubMed PMID: 19364521. 2: Dunlop J, McIlvain HB, Carrick TA, Jow B, Lu Q, Kowal D, Lin S, Greenfield A, Grosanu C, Fan K, Petroski R, Williams J, Foster A, Butera J. Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2. Mol Pharmacol. 2005 Oct;68(4):974-82. Epub 2005 Jul 13. PubMed PMID: 16014807. |
868359-05-1 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.409 ml | 12.043 ml | 24.085 ml |
| 5 mM | 0.482 ml | 2.409 ml | 4.817 ml |
| 10 mM | 0.241 ml | 1.204 ml | 2.409 ml |
| 5 mM | 0.048 ml | 0.241 ml | 0.482 ml |
最后更新：2024-01-02 23:10:35
供应商列表
现货供应
产品名: WAY 213613 去供应商网站查看 询盘CAS: 868359-05-1
产地: 上海
规格: W936788
价格: 10mg-2860
库存: 7天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
提供多种规格
产品名: WAY-213613 hydrochloride 去供应商网站查看 询盘CAS: 868359-05-1(free base)
产地: 上海
规格: 98%
价格: 5mg 1500,10mg 2000,25mg 4500,25mg 12000
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403
微信: 18301782025
产品描述: WAY-213613 hydrochloride 98% MedMol 货号：S89446
现货供应
产品名: WAY 213613 去供应商网站查看 询盘CAS: 868359-05-1
产地: 上海
规格: W936788
价格: 10mg-2860
库存: 7天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
提供多种规格
产品名: WAY-213613 hydrochloride 去供应商网站查看 询盘CAS: 868359-05-1(free base)
产地: 上海
规格: 98%
价格: 5mg 1500,10mg 2000,25mg 4500,25mg 12000
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403
微信: 18301782025
产品描述: WAY-213613 hydrochloride 98% MedMol 货号：S89446
您刚刚浏览过
你知道吗？
微信搜索化工百科或扫描下方二维码，添加化工百科小程序，随时随地查信息！