885066-67-1
PGD2-IN-1(PGD2-IN-1)
CAS: 885066-67-1
化学式: C23H23Cl2N3O3
| 中文名 | PGD2-IN-1 |
| 英文名 | PGD2-IN-1 |
| 别名 | 化合物PGD2-INHIBITOR |
| 英文别名 | MDK66671 PGD2-IN-1 PGD2-inhibitor PGD2 inhibitor 1 prostaglandin D2(PGD2) inhibitor Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl- |
| CAS | 885066-67-1 |
| 化学式 | C23H23Cl2N3O3 |
| 分子量 | 460.35 |
| 密度 | 1.326±0.06 g/cm3(Predicted) |
| 沸点 | 682.1±65.0 °C(Predicted) |
| 溶解度 | DMSO: ≥ 25 mg/mL |
| 酸度系数 | 4.09±0.10(Predicted) |
| 存储条件 | -20℃ |
| 体外研究 | Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion. |
885066-67-1 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.172 ml | 10.861 ml | 21.722 ml |
| 5 mM | 0.434 ml | 2.172 ml | 4.344 ml |
| 10 mM | 0.217 ml | 1.086 ml | 2.172 ml |
| 5 mM | 0.043 ml | 0.217 ml | 0.434 ml |
最后更新：2024-01-02 23:10:35
供应商列表
您刚刚浏览过
你知道吗？
微信搜索化工百科或扫描下方二维码，添加化工百科小程序，随时随地查信息！