906440-37-7
SMBA1(2-[(2-Nitrofluoren-9-ylidene)methyl]phenol)
CAS: 906440-37-7
化学式: C20H13NO3
| 中文名 | SMBA1 |
| 英文名 | 2-[(2-Nitrofluoren-9-ylidene)methyl]phenol |
| 英文别名 | SMBA 1 2-[(2-Nitrofluoren-9-ylidene)methyl]phenol 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol Phenol, 2-[(2-nitro-9H-fluoren-9-ylidene)methyl]- |
| CAS | 906440-37-7 |
| 化学式 | C20H13NO3 |
| 分子量 | 315.32 |
| 密度 | 1.392±0.06 g/cm3(Predicted) |
| 沸点 | 502.0±38.0 °C(Predicted) |
| 溶解度 | DMSO |
| 酸度系数 | 9.22±0.30(Predicted) |
| 存储条件 | -20℃ |
| 产品用途 | SMBA1 is a selective acrivator of Bax, a central death regulator. It acts by potently suppressing lung tumour growth via apoptosis. |
| 参考资料 展开查看 | 1: Levesley J, Steele L, Brüning-Richardson A, Davison A, Zhou J, Ding C, Lawler S, Short SC. Selective BCL-XL inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells. Neuro Oncol. 2018 Jan 22;20(2):203-214. doi: 10.1093/neuonc/nox134. PubMed PMID: 29016820. 2: Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus AI, Sun SY, Chen ZG, Sica GL, Ramalingam SS, Magis AT, Fu H, Khuri FR, Curran WJ, Owonikoko TK, Shin DM, Zhou J, Deng X. Modulation of Bax and mTOR for Cancer Therapeutics. Cancer Res. 2017 Jun 1;77(11):3001-3012. doi: 10.1158/0008-5472.CAN-16-2356. Epub 2017 Apr 5. PubMed PMID: 28381544; PubMed Central PMCID: PMC5503158. 3: Daniele S, Pietrobono D, Costa B, Giustiniano M, La Pietra V, Giacomelli C, La Regina G, Silvestri R, Taliani S, Trincavelli ML, Da Settimo F, Novellino E, Martini C, Marinelli L. Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells. ACS Chem Neurosci. 2018 Jan 17;9(1):85-99. doi: 10.1021/acschemneuro.7b00023. Epub 2017 Apr 11. PubMed PMID: 28368610. 4: Xin M, Li R, Xie M, Park D, Owonikoko TK, Sica GL, Corsino PE, Zhou J, Ding C, White MA, Magis AT, Ramalingam SS, Curran WJ, Khuri FR, Deng X. Small-molecule Bax agonists for cancer therapy. Nat Commun. 2014 Sep 17;5:4935. doi: 10.1038/ncomms5935. PubMed PMID: 25230299; PubMed Central PMCID: PMC4172359. |
906440-37-7 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.171 ml | 15.857 ml | 31.714 ml |
| 5 mM | 0.634 ml | 3.171 ml | 6.343 ml |
| 10 mM | 0.317 ml | 1.586 ml | 3.171 ml |
| 5 mM | 0.063 ml | 0.317 ml | 0.634 ml |
最后更新：2024-01-02 23:10:35
供应商列表
现货供应
产品名: 2-[(2-硝基-9H-芴-9-亚甲基)甲基]苯酚(SMBA 1) 去供应商网站查看 询盘CAS: 906440-37-7
产地: 上海
规格: H780071
价格: 5mg-135,10mg-216,25mg-431
库存: 7天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
现货供应
产品名: 2-[(2-硝基-9H-芴-9-亚甲基)甲基]苯酚(SMBA 1) 去供应商网站查看 询盘CAS: 906440-37-7
产地: 上海
规格: H780071
价格: 5mg-135,10mg-216,25mg-431
库存: 7天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
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