Aldoxorubicin_化工百科

中文名	INNO-206
英文名	INNO-206
别名	化合物 T11090L (E)-N'-[1-[(2S,4S)-4-[[(2R,4S,5S,6S)-4-氨基-5-羟基-6-甲基-2-四氢吡喃基]氧基]-2,5,12-三羟基-7-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-2-并四苯基]-2-羟基亚乙基]-6-(2,5-二氧代-2,5-二氢-1-吡咯基)己酰肼 (E)-N'-(1-((2S,4S)-4-(((2R,4S,5S,6S)-4-氨基-5-羟基-6-甲基四氢-2H-吡喃-2-基基)氧基)-2,5,12-三羟基-7-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢四乙酰-2-基)-2-羟基亚乙基)-6-(2-,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酰肼
英文别名	INNO-206 Aldoxorubicin Aldoxorubicin (INNO-206) Aldoxorubicin Aldoxorubicin DoxorubicinImpurity16Trifluoroacetate N-[(E)-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-6-(2,5-dioxopyrrol-1-yl)hexanamide 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, (2E)-2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide (E)-N'-[1-[(2S,4S)-4-[[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyl-2-tetrahydropyranyl]oxy]-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-2-tetracenyl]-2-hydroxyethylidene]-6-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)hexanehydrazide
CAS	1361644-26-9
化学式	C37H42N4O13
分子量	750.75
密度	1.60±0.1 g/cm3(Predicted)
酸度系数	7.36±0.60(Predicted)
存储条件	-20℃
体外研究	Aldoxorubicin (INNO-206) (0.27 to 2.16 μM) inhibits blood vessel formation and reduces multiple myeloma cell growth in a pH-dependent fashion.
体内研究	Aldoxorubicin (INNO-206) (10.8 mg/kg, i.v.) shows significantly smaller tumor volumes and IgG levels on days 28, and is well tolerated with 90% of mice surviving until the termination of the study in the mice bearing the LAGκ-1A tumor. Aldoxorubicin (INNO-206) shows a good safety profile at doses up to 260 mg/mL doxorubicin equivalents, and is able to induce tumor regressions in breast cancer, small cell lung cancer and sarcoma in phase I study. Aldoxorubicin (INNO-206) shows superior activity over doxorubicin in a murine renal cell carcinoma model and in breast carcinoma xenograft models.

Aldoxorubicin - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	1.332 ml	6.66 ml	13.32 ml
5 mM	0.266 ml	1.332 ml	2.664 ml
10 mM	0.133 ml	0.666 ml	1.332 ml
5 mM	0.027 ml	0.133 ml	0.266 ml

最后更新：2024-01-02 23:10:35

北京索莱宝科技有限公司

现货供应

产品名: Aldoxorubicin 去供应商网站查看询盘
CAS: 1361644-26-9
产地: 北京
包装: 盒
规格: IA6520-1mg,1mg
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上海吉至生化科技有限公司

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产品名: Aldoxorubicin 去供应商网站查看询盘
CAS: 1361644-26-9
产地: 中国上海
包装: 100mg
规格: 95%
价格: 11798.00
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产品描述: 中文名：Aldoxorubicin 英文名:Aldoxorubicin CAS:1361644-26-9 规格:95% 产地:中国上海

上海麦克林生化科技股份有限公司

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产品名: Aldoxorubicin 去供应商网站查看询盘
CAS: 1361644-26-9
产地: 上海
规格: A882982
价格: 2mg-992,5mg-1836,25mg-6120
库存: 现货
电话: 13816333479/17821173903
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上海源叶生物科技有限公司

产品名: INNO-206 去供应商网站查看询盘
CAS: 1361644-26-9
产地: 上海
规格: 95%
价格: 5mg 1350,10mg 1740,50mg 6950
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
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