中文名 | 叠氮-三聚乙二醇-对甲基苯磺酰酯 |
英文名 | 2-(2-(2-azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate |
别名 | 叠氮-三聚乙二醇-对甲苯磺酰酯 叠氮-三聚乙二醇-对甲基苯磺酰酯 |
英文别名 | N3-PEG3-Tos N3-PEG3-OTs Azide-PEG3-Tos Azido-PEG3-Ots 2-(2-(2-Azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate 2-(2-(2-azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate Toluene-4-sulfonic acid 2-[2-(2-azido-ethoxy)-ethoxy]-ethyl ester Ethanol, 2-[2-(2-azidoethoxy)ethoxy]-, 4-methylbenzenesulfonate (ester) |
CAS | 178685-33-1 |
化学式 | C13H19N3O5S |
分子量 | 329.37 |
存储条件 | 室温,干燥,密封 |
外观 | 液体 |
体外研究 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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