中文名 | 双(麦芽醇)氧钒(IV) |
英文名 | Bis(maltolato)oxovanadium(IV) |
别名 | 双(麦芽醇)氧钒(IV) |
英文别名 | BMOV BIS(MALTOLATO)OXOVANADIUM Bis(maltolato)oxovanadium(IV) BIS(MALTOLATO)OXOVANADIUM(IV) oxovanadium(2+) bis(2-methyl-4-oxo-4H-pyran-3-olate) (SP-5-31)-Bis[3-(hydroxy-κO)-2-Methyl-4H-pyran-4-onato-κO4]oxovanadiuM Vanadium,bis[3-(hydroxy-kO)-2-methyl-4H-pyran-4-onato-kO4]oxo-, (SP-5-31)- Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium |
CAS | 38213-69-3 |
化学式 | C12H10O7V |
分子量 | 317.15 |
熔点 | >300°C (dec.) |
水溶性 | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
溶解度 | DMSO (微溶) 、甲醇 (微溶) 、水 (微溶) |
存储条件 | Refrigerator |
外观 | 粉末 |
颜色 | yellow to grey to brown |
体外研究 | Bis(maltolato)oxovanadium(IV) treatment enhances the phosphorylation of the insulin receptor and of the insulin signalling key intermediate Akt. Bis(maltolato)oxovanadium(IV) (BMOV; 50 μM) treatment also resultes in an increased glucose uptake in C2C12 cells. |
体内研究 | Bis(maltolato)oxovanadium(IV) (BMOV; 0.75-3.0 mmol; intraperitoneal injection; twice weekly; for 6 weeks; C57BL/6J mice) treatment ameliorates the metabolic phenotype. Liver, skeletal muscle, and adipose tissue revealed a significantly reduced PTP activity in all analysed tissues compared to HFD mice. Animal Model: C57BL/6J mice (4-6 weeks) fed with high-fat diet (HFD) Dosage: 0.75-3.0 mmol Administration: Intraperitoneal injection; twice weekly; for 6 weeks Result: Ameliorated the metabolic phenotype, as evidenced by reduced body weight, improved insulin sensitivity and glucose tolerance. |
危险品运输编号 | UN 2811 6.1 / PGIII |
WGK Germany | 3 |
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