中文名 | Bobcat339 |
英文名 | Bobcat339 |
别名 | 盐酸BOBCAT339 1-([1,1'-联苯]-3-基)-4-氨基-5-氯嘧啶-2(1H)-酮 |
英文别名 | Bobcat399 Bobcat339 5.BOBCAT339 Bobcat339(Bobcat 339) 1-([1,1'-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one 2(1H)-Pyrimidinone, 4-amino-1-[1,1'-biphenyl]-3-yl-5-chloro- |
CAS | 2280037-51-4 |
EINECS | 604-604-1 |
化学式 | C16H12ClN3O |
分子量 | 297.74 |
密度 | 1.33±0.1 g/cm3(Predicted) |
沸点 | 489.0±55.0 °C(Predicted) |
溶解度 | DMSO: 2 mg/ml,澄清 |
酸度系数 | 2.42±0.10(Predicted) |
存储条件 | -20°C |
产品用途 | Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.359 ml | 16.793 ml | 33.586 ml |
5 mM | 0.672 ml | 3.359 ml | 6.717 ml |
10 mM | 0.336 ml | 1.679 ml | 3.359 ml |
5 mM | 0.067 ml | 0.336 ml | 0.672 ml |
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