Carabersat_化工百科

中文名	Carabersat
英文名	Carabersat
别名	卡拉博沙化合物 T14863
英文别名	Carabersat Benzamide, N-[(3R,4S)-6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-4-fluoro-
CAS	184653-84-7
化学式	C20H20FNO4
分子量	357.38
密度	1.31±0.1 g/cm3(Predicted)
沸点	559.3±50.0 °C(Predicted)
酸度系数	13.05±0.60(Predicted)
存储条件	-20℃
体外研究	[ 3 H]Carabersat ([ 3 H]SB 204269) binds to rat forebrain membranes with moderate affinity (K d 40 nM) and pK i values of 7.3. Carabersat is able to bind to mouse forebrain membranes, and the binding is saturable and stereospecific, with a K d of 53 nM. The labelled [ 3 H]Carabersat produces a K d of 32 nM. Carabersat (SB-204269, 1-100 μM) has no effect on Na + current in cultured hippocampal neurones. Carabersat also shows no effect on action potential discharges evoked by elevating external K + . Carabersat (SB-204269) is structurally-related to the benzopyran ATP-sensitive potassium channel (KATP) opener, cromakalim, but has opposite stereochemistry, and the mechanism of action of Carabersat is not thought to involve KATP.
体内研究	Carabersat (5b) significantly elevates anticonvulsant activity in mice.

上海麦克林生化科技股份有限公司

现货供应

产品名: Carabersat 去供应商网站查看询盘
CAS: 184653-84-7
产地: 上海
规格: C881076
价格: 5mg-10260,1mg-5175
库存: 15天内发货
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上海源叶生物科技有限公司

产品名: Carabersat 去供应商网站查看询盘
CAS: 184653-84-7
产地: 上海
规格: 98%
价格: 1mg 7080,5mg 14040
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