中文名 | Enpatoran |
英文名 | 5-((3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl)quinoline-8-carbonitrile |
英文别名 | M5049 Enpatoran 5-((3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl)quinoline-8-carbonitrile 8-Quinolinecarbonitrile, 5-[(3R,5S)-3-amino-5-(trifluoromethyl)-1-piperidinyl]- |
CAS | 2101938-42-3 |
化学式 | C16H15F3N4 |
分子量 | 320.31 |
溶解度 | 溶于DMSO |
存储条件 | -20℃ |
产品用途 | Enpatoran is a toll-Like receptor antagonist. |
靶点 | TLR7;TLR8 |
参考资料 展开查看 | 1. Jaromir Vlach, et al. Discovery of M5049: A Novel Selective TLR7/8 Inhibitor for Treatment of Autoimmunity. J Pharmacol Exp Ther. 2020 Dec 16;JPET-AR-2020-000275. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.122 ml | 15.609 ml | 31.219 ml |
5 mM | 0.624 ml | 3.122 ml | 6.244 ml |
10 mM | 0.312 ml | 1.561 ml | 3.122 ml |
5 mM | 0.062 ml | 0.312 ml | 0.624 ml |
微信搜索化工百科或扫描下方二维码,添加化工百科小程序,随时随地查信息!