Etripamil
Etripamil(Etripamil)
CAS: 1593673-23-4
化学式: C27H36N2O4
| 中文名 | Etripamil |
| 英文名 | Etripamil |
| 别名 | 化合物ETRIPAMIL |
| 英文别名 | MSP-2017 Etripamil (-)-MSP-2017 Benzoic acid, 3-[2-[[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]methylamino]ethyl]-, methyl ester |
| CAS | 1593673-23-4 |
| 化学式 | C27H36N2O4 |
| 分子量 | 452.59 |
| 密度 | 1.079±0.06 g/cm3(Predicted) |
| 沸点 | 593.8±50.0 °C(Predicted) |
| 溶解度 | 溶于DMSO |
| 酸度系数 | 8.92±0.50(Predicted) |
| 存储条件 | -20℃ |
| 产品用途 | Etripamil is a calcium channel blocker. Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are several medications that disrupt the movement of calcium (Ca2+) through calcium channels. Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension. |
| 参考资料 展开查看 | [1]. Stambler BS, et al. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. J Am Coll Cardiol. 2018 Jul 31;72(5):489-497.[2]. Milestone Pharmaceuticals Announces USAN Approval of Generic Name “Etripamil” for its Phase 2 Clinical Development Product for the Treatment of Paroxysmal Supraventricular Tachycardia. |
Etripamil - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.21 ml | 11.048 ml | 22.095 ml |
| 5 mM | 0.442 ml | 2.21 ml | 4.419 ml |
| 10 mM | 0.221 ml | 1.105 ml | 2.21 ml |
| 5 mM | 0.044 ml | 0.221 ml | 0.442 ml |
最后更新：2024-01-02 23:10:35
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