HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE

中文名	HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE
英文名	H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH
别名	髓鞘蛋白脂蛋白髓鞘蛋白脂蛋白H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH
英文别名	PLP (HUMAN, BOVINE, DOG, MOUSE, RAT) HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH PLP (139-151) (DEPALMITOYLATED) (HUMAN, BOVINE, DOG, MOUSE, RAT) MYELIN PROTEOLIPID PROTEIN (139-151) (HUMAN, BOVINE, DOG, MOUSE, RAT) LIPOPHILIN (139-151) (DEPALMITOYLATED) (HUMAN, BOVINE, DOG, MOUSE, RAT) MYELIN PROTEOLIPID PROTEIN (139-151) (DEPALMITOYLATED) (HUMAN, BOVINE, DOG, MOUSE, RAT) H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH (HUMAN, BOVINE, DOG, MOUSE, RAT)
CAS	131334-43-5
化学式	C72H104N20O16S
分子量	1537.79
密度	1.332±0.06 g/cm3(Predicted)
沸点	1897.4±65.0 °C(Predicted)
酸度系数	3.49±0.10(Predicted)
存储条件	Room Temprature
外观	白色至灰白色粉末。
体外研究	Severe clinical and histological EAE could be induced by adoptive transfer of the peptide-specific T cell line and 3 of 4 T cell clones. The T cell line/clones all responded strongly to PLP (139-151) in in vitro proliferative assays. Line SPL and all of the clones show strong proliferative response to the whole PLP molecule and to PLP (139-151).
体内研究	PLP (139-151) induces acute experimental allergic encephalomyelitis (EAE) in SJL/J mice. Beginning on Day 9, the mice treated with PLP (139-151) show signs of EAE and the disease progressed rapidly to paralysis. Central nervous system inflammation, edema, gliosis, and demyelination are found in all mice killed between Days 10 and 28. Young male SJL mice immunized with a major encephalitogenic peptide of myelin, PLP 139-151, develop initial clinical and histological symptoms of EAE with a severity similar to age-matched females; however, unlike females, male mice does not relapse. Significant T cell proliferation to PLP 139-151, but not to other PLP and myelin basic protein (MBP) epitopes, is observed in both males and females during the initial episode, recovery, and first relapse of clinical disease.

HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE - 简介

HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE是一种多肽，它由13个氨基酸组成。以下是该多肽的一些性质，用途，制法和安全信息：

性质：
化学性质稳定：HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE在中性或弱酸性条件下相对稳定。
生物活性：该多肽可能具有生物活性，例如具有抗菌、抗氧化、抗炎和免疫调节等作用。

用途：

制法：
化学合成：HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE可以通过化学合成方法制备，其中各个氨基酸单元按照特定的顺序连接起来构成多肽链。

安全信息：
毒性：关于HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE的毒性尚未明确，因为多肽的毒性通常取决于具体的结构和剂量。
安全操作：在操作HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE时，应遵守实验室安全操作规程，使用适当的防护措施，避免直接接触皮肤和粘膜，避免误食。

最后更新：2024-04-09 19:05:18

北京索莱宝科技有限公司

现货供应

产品名: PLP (139-151) 去供应商网站查看询盘
CAS: 131334-43-5
产地: 北京
包装: 盒
规格: IP5040-1mg,1mg,IP5040-5mg,5mg
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库存: 现询
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上海麦克林生化科技股份有限公司

现货供应

产品名: PLP 139-151 去供应商网站查看询盘
CAS: 131334-43-5
产地: 上海
规格: P883290
价格: 1mg-941,5mg-3706
库存: 7天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
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上海源叶生物科技有限公司

产品名: HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE 去供应商网站查看询盘
CAS: 131334-43-5
产地: 上海
规格: ≥98%
价格: 1mg 1200,5mg 4760
电话: 18301782025
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QQ: 3008007403