中文名 | 甘氨脱氧胆酸一水合物 |
英文名 | Glycodeoxycholic acid monohydrate |
别名 | 甘氨去氧胆酸 苷氨脱氧胆酸 甘油脱氧胆酸 甘氨脱氧胆酸 甘氨脱氧胆酸对照品 甘氨脱氧胆酸一水合物 甘氨脱氧胆酸(GDCA) N-(3Α,12Α-二羟基-24-氧胆)甘氨酸 |
英文别名 | deoxycholylglycine glykodesoxycholsaeure Glycodeoxycholic acid monohydrate glycodeoxy-5-beta-cholan-24-oicaci N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine n-(3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-yl)-glycin 3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide n-((3-alpha,5-beta,12-alpha)-3,12-dihydroxy-24-oxocholan-24-yl)-glycine 2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid |
CAS | 360-65-6 |
化学式 | C26H43NO5 |
分子量 | 449.63 |
密度 | 1.162±0.06 g/cm3(Predicted) |
熔点 | 184 °C |
沸点 | 655.6±50.0 °C(Predicted) |
溶解度 | 乙腈 (微溶) 、乙醇 (微溶) 、甲醇 (微溶) |
酸度系数 | pKa 3.87±0.06(H2O,t = 25.0±0.1,I=0.00) (Uncertain) |
存储条件 | 2-8°C |
外观 | 固体 |
颜色 | White to Off-White |
MDL号 | MFCD00150922 |
危险品标志 | Xi - 刺激性物品 |
风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
安全术语 | 26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 |
WGK Germany | 3 |
RTECS | MB9670000 |
FLUKA BRAND F CODES | 10 |
上游原料 | 去氧胆酸 甘氨脱氧胆酸乙酯 甘氨酸 |
参考资料 展开查看 | 1. Song Lin, Tian-yang Wang, Hua-rong Xu, Xin-nong Zhang, Qi Wang, Ran Liu, Qing Li, Kai-shun Bi,A systemic combined nontargeted and targeted LC-MS based metabolomic strategy of plasma and liver on pathology exploration of alpha-naphthylisothiocyanate induce 2. [IF=5.396] Shiming Huang et al."A sulfated polysaccharide from Gracilaria Lemaneiformis regulates cholesterol and bile acid metabolism in high-fat diet mice."Food Funct. 2019 Jun;10(6):3224-3236 3. [IF=5.34] Kaihui Zhang et al."A UPLC-MS/MS-based metabolomics analysis of the pharmacological mechanisms of rabdosia serra against cholestasis."Phytomedicine. 2021 Oct;91:153683 4. [IF=3.935] Song Lin et al."A systemic combined nontargeted and targeted LC-MS based metabolomic strategy of plasma and liver on pathology exploration of alpha-naphthylisothiocyanate induced cholestatic liver injury in mice."J Pharmaceut Biomed. 2019 Jul;171:180 5. [IF=3.935] Runjing Zhang et al."Xiaoyan lidan formula ameliorates α-naphthylisothiocyanate-induced intrahepatic cholestatic liver injury in rats as revealed by non-targeted and targeted metabolomics."J Pharmaceut Biomed. 2020 Feb;179:112966 6. [IF=1.618] Chen Mengjun et al."A Powerful HPLC-ELSD Method for Simultaneous Determination of Fecal Bile Acids in T2DM Rats Interfered by Sanhuang Xiexin Tang."J Chromatogr Sci. 2021 Sep;59(9):871-876 7. [IF=1.618] Chen Mengjun et al."A Powerful HPLC-ELSD Method for Simultaneous Determination of Fecal Bile Acids in T2DM Rats Interfered by Sanhuang Xiexin Tang."J Chromatogr Sci. 2021 Sep;59(9):871-876 8. [IF=5.396] Juan Wu et al."Sargassum fusiforme polysaccharide is a potential auxiliary substance for metformin in the management of diabetes."Food Funct. 2022 Feb;: 9. [IF=6.558] Yan Cao et al."Widely quasi-quantitative analysis enables temporal bile acids-targeted metabolomics in rat after oral administration of ursodeoxycholic acid."ANALYTICA CHIMICA ACTA. 2022 Jun;1212:339885 10. [IF=6.558] Yan Cao et al."Widely quasi-quantitative analysis enables temporal bile acids-targeted metabolomics in rat after oral administration of ursodeoxycholic acid."ANALYTICA CHIMICA ACTA. 2022 Jun;1212:339885 |
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