中文名 | OUN67600 |
英文名 | 4(3H)-Quinazolinone, 8-fluoro-3-[4-(4-fluorophenoxy)phenyl]-2-(4-methyl-1-piperazinyl)-, hydrochloride (1:1) |
别名 | 化合物TRPV4 AGONIST-1 |
英文别名 | OUN67600 TRPV4 agonist RPV4 agonist-1 TRPV4 agonist-1 OUN67600(TRPV4 agonist-1) |
CAS | 2314467-60-0 |
化学式 | C25H23ClF2N4O2 |
分子量 | 484.93 |
溶解度 | 溶于DMSO |
存储条件 | -20℃ |
产品用途 | OUN67600, is a Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonist as Regulators of Chondrogenic Differentiation. |
参考资料 展开查看 | Atobe M, Nagami T, Muramatsu S, Ohno T, Kitagawa M, Suzuki H, Ishiguro M, Watanabe A, Kawanishi M. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Feb 14;62(3):1468-1483. doi: 10.1021/acs.jmedchem.8b01615. Epub 2019 Jan 28. PMID: 30629441. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.062 ml | 10.311 ml | 20.621 ml |
5 mM | 0.412 ml | 2.062 ml | 4.124 ml |
10 mM | 0.206 ml | 1.031 ml | 2.062 ml |
5 mM | 0.041 ml | 0.206 ml | 0.412 ml |
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