Qstatin
Qstatin(Qstatin)
CAS: 902688-24-8
化学式: C7H5BrN2O2S2
| 中文名 | Qstatin |
| 英文名 | Qstatin |
| 别名 | 化合物QSTATIN 1-((5-溴噻吩-2-基)磺酰基)-1H-吡唑 |
| 英文别名 | Qstatin 1H-Pyrazole, 1-[(5-bromo-2-thienyl)sulfonyl]- 1-((5-Bromothiophen-2-yl)sulfonyl)-1H-pyrazole |
| CAS | 902688-24-8 |
| 化学式 | C7H5BrN2O2S2 |
| 分子量 | 293.16 |
| 密度 | 1.93±0.1 g/cm3(Predicted) |
| 沸点 | 446.3±55.0 °C(Predicted) |
| 溶解度 | DMSO: 83.33毫克/毫升 (284.25毫米; 需要超声波) |
| 酸度系数 | -5.76±0.19(Predicted) |
| 存储条件 | under inert gas (nitrogen or Argon) at 2–8 °C |
| 体外研究 | QStatin (0.001 μM-10 μM; 5 hours) inhibits SmcR activity measured by the RLU level for V. vulnificusWT (pBB1), reveals EC 50 of 208.9 nM. QStatin (5 μM-50 μM; 16 hours) reduces the activities of SmcR-activated virulence factors (protease and elastase) in V. vulnificus in a dose dependent manner. QStatin (5 μM-50 μM; 16 hours) has no effect on the cellular levels of SmcR, indicating that QStatin does not affect the expression or stability of SmcR. |
Qstatin - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.411 ml | 17.056 ml | 34.111 ml |
| 5 mM | 0.682 ml | 3.411 ml | 6.822 ml |
| 10 mM | 0.341 ml | 1.706 ml | 3.411 ml |
| 5 mM | 0.068 ml | 0.341 ml | 0.682 ml |
最后更新：2024-01-02 23:10:35
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