中文名 | alpha-熊果苷 |
英文名 | alpha-Arbutin |
别名 | α-熊果苷 alpha-熊果甙 alpha-熊果苷 ALPHA-熊果苷(标准品) 4-羟基苯基Α-D-吡喃葡糖苷 4-羟基苯-α-D-吡喃葡萄糖苷 对苯二酚-alpha-D-葡萄糖苷 4-氢苯醌-alpha-D-吡喃葡萄糖甙 4-氢苯醌-ALPHA-D-吡喃葡萄糖苷 |
英文别名 | α-Arbutin a-Arbutin alpha-Arbutin alpha-arbutin Alpha Arbutin Powder Hydroquinone O-α-D-Glucopyranoside 4-Hydroxyphenyl a-D-glucopyranoside 4-Hydroquinone-alpha-D-glucopyranoside 4-hydroquinone-alpha-d-glucopyranoside 4-hydroxyphenyl alpha-D-glucopyranoside (2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL |
CAS | 84380-01-8 |
EINECS | 209-795-0 |
化学式 | C12H16O7 |
分子量 | 272.25 |
InChI | InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1 |
InChIKey | BJRNKVDFDLYUGJ-ZIQFBCGOSA-N |
密度 | 1.556±0.06 g/cm3(Predicted) |
熔点 | 195-196°C |
沸点 | 561.6±50.0 °C(Predicted) |
闪点 | 293.4°C |
蒸汽压 | 1.9E-13mmHg at 25°C |
溶解度 | DMSO (微溶) 、甲醇 (微溶) |
折射率 | 1.65 |
酸度系数 | 10.10±0.15(Predicted) |
存储条件 | 2-8°C |
外观 | 固体 |
颜色 | White to Off-White |
BRN | 89675 |
物化性质 | 白色针状结晶,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于熊果叶,岩白菜。 |
MDL号 | MFCD09838262 |
WGK Germany | 3 |
参考资料 展开查看 | 1. 滕希峰 李钟 刘龙元 等. α-熊果苷平衡溶解度 表观油水分配系数和解离常数的测定[J]. 中成药 2016 38(11):2366-2366. 2. 李晓玉, 夏媛媛, 沈微,等. 肠膜明串珠菌蔗糖磷酸化酶的酶学表征及在催化合成α-熊果苷中的应用[J]. 生物工程学报 2020年36卷8期, 1546-1555页, MEDLINE ISTIC PKU CSCD CA, 2020. 3. 熊时鹏, 陈建波. 多光谱法和分子对接研究α-熊果苷与人血清白蛋白的相互作用[J]. 光谱学与光谱分析, 2018, 38(011):3489-3494. 4. 李晓玉,夏媛媛,沈微,杨海泉,曹钰,陈献忠.肠膜明串珠菌蔗糖磷酸化酶的酶学表征及在催化合成α-熊果苷中的应用[J].生物工程学报,2020,36(08):1546-1555. 5. Tang, Xiaoqing, Weixi Cai, and Baojun Bruce Xu. "Comparison of the chemical profiles and antioxidant and antidiabetic activities of extracts from two Ganoderma species (Agaricomycetes)." International journal of medicinal mushrooms 18.7 (2016).10.1615/IntJ 6. [IF=9.783] Huiping Bi et al."Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction."Metab Eng. 2022 Jan;69:15 7. [IF=2.629] Ding Yaqi et al."α-Arbutin Protects Against Parkinson’s Disease-Associated Mitochondrial Dysfunction In Vitro and In Vivo."Neuromol Med. 2020 Mar;22(1):56-67 8. [IF=5.645] Jing Xie et al."Chemical compounds, anti-aging and antibacterial properties of Rosa rugosa Purple branch."Ind Crop Prod. 2022 Jul;181:114814 9. [IF=6.312] Wei Wang et al."Kojic Acid Showed Consistent Inhibitory Activity on Tyrosinase from Mushroom and in Cultured B16F10 Cells Compared with Arbutins."Antioxidants-Basel. 2022 Mar;11(3):502 |
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