小鼠静腔注射,LD50 4~5g/kg。有肠胃道机能紊乱、失眠、头痛、发热。大剂量或注射过速可出现血压降低、呼吸抑制、肌无力、运动失调等。滴注过程中有不良反应,应立即停药
中文名 | 4-氨基丁酸 |
英文名 | 4-Aminobutyric acid |
别名 | 氨酪酸 氨酷酸 丁氨酸 氨基丁酸 γ-氨基丁酸 伽马氨基丁酸 4-氨基丁酸 gamma-氨基丁酸 Γ-氨基丁酸(标准品) Γ-氨基丁酸(GABA) Γ-氨基丁酸(4-氨基丁酸) 4(GAMMA)-氨基丁酸(氨酪酸) γ-氨基丁酸(氨己烯酸杂质) |
英文别名 | Gaba aurora ka-1053 AURORA KA-1053 piperidic acid piperidinic acid 4-AMINOBUTYRIC ACID 4-Aminobutyric acid γ-aminobutyric acid aminobutyric-4 acid AMINOBUTYRIC-4 ACID 4-amino butyric acid 4-AMINOBUTANOIC ACID 4-aminobutanoic acid h-4-aminobutyric acid AMINOBUTYRIC ACID, 4- H-4-AMINOBUTYRIC ACID aminobutyric acid, 4- 4-AMINO-N-BUTYRIC ACID 4-amino-n-butyric acid gamma-aminobutyric acid gamma aminobutyric acid ALPHA-AMINOBUTANOIC ACID gamma.-aminobutyric acid alpha-aminobutanoic acid |
CAS | 56-12-2 |
EINECS | 200-258-6 |
化学式 | C4H9NO2 |
分子量 | 103.12 |
InChI | InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
InChIKey | BTCSSZJGUNDROE-UHFFFAOYSA-N |
密度 | 1.2300 (estimate) |
熔点 | 195 °C (dec.) (lit.) |
沸点 | 248.0±23.0 °C(Predicted) |
闪点 | 103.8°C |
水溶性 | SOLUBLE |
蒸汽压 | 0.00798mmHg at 25°C |
JECFA Number | 1771 |
溶解度 | H2O: 1m在20 °C,澄清,无色 |
折射率 | 1.4650 (estimate) |
酸度系数 | 4.031(at 25℃) |
存储条件 | 2-8°C |
外观 | 粉末 |
颜色 | White to almost white |
Merck | 14,430 |
BRN | 906818 |
物化性质 | 白色片状或针状结晶;微臭,具有潮解性;极易溶于水,微溶于热乙醇,不溶于冷乙醇、乙醚和苯;分解点为202℃;LD50(大鼠,腹腔) 5400mg/kg。 |
MDL号 | MFCD00008226 |
危险品标志 | Xi - 刺激性物品 Xn - 有害物品 |
风险术语 | R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 R20/21/22 - 吸入、皮肤接触及吞食有害。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36 - 穿戴适当的防护服。 |
WGK Germany | 2 |
RTECS | ES6300000 |
TSCA | Yes |
海关编号 | 29224995 |
Hazard Note | Irritant |
上游原料 | 碳酸氢铵 玉米浆 己酰氯 强酸性苯乙烯系阳离子交换树脂 4-氯丁腈 邻苯二甲酰亚胺钾 N,N,N-三(聚氧丙烯聚氧乙烯)胺 |
下游产品 | 4-马来酰亚胺丁酸 阿仑膦酸 2-羟基-4-氨基丁酸 4-(1,3-二氧代异吲哚啉-2-基)丁酸 |
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小鼠静腔注射,LD50 4~5g/kg。有肠胃道机能紊乱、失眠、头痛、发热。大剂量或注射过速可出现血压降低、呼吸抑制、肌无力、运动失调等。滴注过程中有不良反应,应立即停药
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