中文名 | 人促肾上腺皮质激素18-39 |
英文名 | CLIP |
别名 | 人促肾上腺皮质激素18-39 人ACTH (18-39)肽 |
英文别名 | CLIP RF-22 CLIP (HUMAN) ACTH (18-39) (HUMAN) corticotropin-likeintermediatelobepeptide Corticotropin-Like InterMediate Peptide (CLIP) Adrenocorticotropic Hormone (ACTH) (18-39), human ProteoMass? ACTH Fragment 18-39 MALDI-MS Standard ProteoMass(R) ACTH FragMent 18-39 MALDI-MS Standard ACTH (18-39) (huMan) Corticotropin-Like InterMediate Peptide (CLIP) H-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH |
CAS | 53917-42-3 |
化学式 | C112H165N27O36 |
分子量 | 2465.67 |
密度 | 1.49±0.1 g/cm3(Predicted) |
存储条件 | -20°C |
体外研究 | The ACTH family of polypeptides consists of ACTH(1-39) (adrenocorticotropin), ACTH (1-13)amide (α-melanotropin;α-MSH); and ACTH (18-39) (corticotropinlike intermediate lobe peptide, CLIP). These polypeptides are derived from a common precursor, proopiomelanocortin. In corticotropic cells of the pars distalis, proopiomelanocortin (POMC) undergoes a series of proteolytic cleavage reactions to yield ACTH (1-39) as a major end product. However, in the melanotropic cells of the pars intermedia, an additional set of proteolytic reactions results in the conversion of ACTH (1-39) to ACTH (1-13) amide and ACTH (18-39). In several species of vertebrates, ACTH (1-13) amide undergoes end product modification to yield mono- and diacetylated forms ofα-MSH as major end products in the pars intermedia. |
WGK Germany | 3 |
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