去乙酰车叶草苷酸
去乙酰车叶草苷酸(Deacetyl asperulosidic acid)
CAS: 14259-55-3
化学式: C16H22O11
| 中文名 | 去乙酰车叶草苷酸 |
| 英文名 | Deacetyl asperulosidic acid |
| 别名 | 去乙酰基车叶草酸 去乙酰车叶草苷酸 去乙酰基车叶草苷酸 10去乙酰天冬氨酸 去乙酰基车叶草苷酸标准品 去乙酰基车叶草苷酸对照品 化合物SBE 13 HYDROCHLORIDE |
| 英文别名 | Deacetyl asperulosidic acid Desacetyl asperulosidic acid deacethyl asperulosidic acid Asperulosidic Acid Impurity 2 (Desacetylasperulosidic Acid) (1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid (1S,4aS,5S,7aS)-1-(b-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid (1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-(hydroxymet hyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid Cyclopenta[c]pyran-4-carboxylicacid, 1-(b-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)-,(1S,4aS,5S,7aS)- Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)-, (1S,4aS,5S,7aS)- |
| CAS | 14259-55-3 |
| 化学式 | C16H22O11 |
| 分子量 | 390.34 |
| 密度 | 1.73 |
| 沸点 | 744.1±60.0 °C(Predicted) |
| 比旋光度 | (c, 1.7 in MeOH)+26 |
| 溶解度 | 可溶于水，碱性溶液，不溶于石油醚。 |
| 酸度系数 | 4.34±0.70(Predicted) |
| 存储条件 | 2-8℃ |
| 外观 | 白色粉末 |
| 物化性质 | 白色结晶粉末，溶于甲醇，乙醇，乙酸乙酯，几乎不溶于水，来源于猪殃殃、巴戟天、白花蛇舌草。 |
| MDL号 | MFCD21364062 |
| 参考资料 展开查看 | 1. 沈燚,何玉琼,张奇,刘梦琴,辛海量,张泉龙,秦路平,张巧艳.巴戟天环烯醚萜苷类成分的制备及其对破骨细胞骨吸收的抑制作用[J].第二军医大学学报,2019,40(02):149-156. 2. 史悦华 闫秋莹 范汇森 等. UHPLC-MS/MS技术同时测定大鼠灌胃白花蛇舌草水提取液后血浆中3种二萜类成分含量及其药代动力学研究[J]. 药物分析杂志 2019 039(005):813-820. 3. He, Jingyu, et al. "Asperuloside and asperulosidic acid exert an anti-inflammatory effect via suppression of the NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages." International journal of molecular sciences 19.7 (2018): 2027.https:// 4. [IF=4.183] Jingyu He et al."Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages."Int J Mol Sci. 2018 Jul;19(7):2027 5. [IF=3.659] Shen Yi et al."Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats."Bmc Complem Altern M. 2018 Dec;18(1):1-12 6. [IF=5.878] Li DanQing et al."N-butanol extract of Hedyotis diffusa protects transgenic Caenorhabditis elegans from Aβ-induced toxicity."Phytother Res. 2021 Feb;35(2):1048-1061 7. [IF=5.34] Wei Zou et al."Imperatae rhizoma-Hedyotis diffusa Willd. herbal pair alleviates nephrotic syndrome by integrating anti-inflammatory and hypolipidaemic effects."Phytomedicine. 2021 Sep;90:153644 8. [IF=2.447] Jianrong Chen et al."Anti‑inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos."Exp Ther Med. 2021 Jul;22(1):1-9 |
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