中文名 | 咖啡酸 |
英文名 | 3,4-Dihydroxycinnamic acid |
别名 | 咖啡酸 咖啡酸(3 水解咖啡鞣酸 咖啡酸, 反式为主 3,4-二羟基肉桂酸 3,4-二羟基苯乙烯酸 β-(3,4-二羟苯基)丙烯酸 |
英文别名 | Caffeicacid Caffeic acid CAFFEIC ACID TIMTEC-BB SBB006475 RARECHEM BK HC T335 3,4-Dihydroxycinnamic acid 3-(3,4-DIHYDROXYPHENYL)ACRYLIC ACID 3-(3,4-dihydroxyphenyl)prop-2-enoic acid 4-(2'-carboxyvinyl)-1,2-dihydroxybenzene 3-(3,4-DIHYDROXYPHENYL)-2-PROPENOIC ACID 4-(2'-Carboxyvinyl)-1,2-dihydroxybenzene 4-(2-Carboxyethenyl)-1,2-dihydroxybenzene (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid (2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid |
CAS | 331-39-5 |
EINECS | 206-361-2 |
化学式 | C9H8O4 |
分子量 | 180.16 |
InChI | InChI=1/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/p-1/b4-2+ |
InChIKey | QAIPRVGONGVQAS-DUXPYHPUSA-N |
密度 | 1.2933 (rough estimate) |
熔点 | 211-213 °C (dec.) (lit.) |
沸点 | 272.96°C (rough estimate) |
闪点 | 220°C |
水溶性 | soluble in hot water |
蒸汽压 | 1.08E-07mmHg at 25°C |
溶解度 | 乙醇: 50mg/ml |
折射率 | 1.4500 (estimate) |
酸度系数 | 4.58±0.10(Predicted) |
存储条件 | 2-8°C |
稳定性 | 稳定。可燃。与强氧化剂、强碱不相容。 |
敏感性 | Easily absorbing moisture |
外观 | 粉末 |
颜色 | yellow to tan |
Merck | 14,1635 |
BRN | 2210883 |
物化性质 | 外观呈黄色结晶,可溶于热水及乙醇。 |
MDL号 | MFCD00004392 |
危险品标志 | Xn - 有害物品 Xi - 刺激性物品 |
风险术语 | R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 R40 - 少数报道有致癌后果。 R63 - 可能有对胎儿造成伤害的危险。 R68 - 可能有不可逆后果的危险。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S36 - 穿戴适当的防护服。 |
WGK Germany | 3 |
RTECS | GD8950000 |
海关编号 | 29182990 |
Hazard Note | Irritant |
上游原料 | 右旋奎宁酸 |
下游产品 | 咖啡酸 4,5-二羟基-2-硝基苯甲醛 |
参考资料 展开查看 | 1. 霍梦恩, 李冬利, 罗小燕,等. 陈年乌龙茶的生化成分及其降脂降糖活性研究[J]. 茶叶通讯, 2019, 046(004):472-478. 2. 梁娜. 冰葡萄中7种成分含量测定方法的比较研究[D].辽宁中医药大学 2019. 3. 闫征 王四维. 咖啡酸对模拟饮料体系中黑米花色苷的辅色作用研究[J]. 农产品加工 2015 No.395(21):1-3. 4. 张慧, 李思雨, 冯宏玲,等. 基于效应成分指数的双黄连制剂质量控制研究[J]. 药学学报, 2019, 054(012):2149-2154. 5. 胡欣彤, 丁丽琴, 李巍,等. 大鼠ig牡丹皮提取物后丹皮酚及其代谢产物的药动学研究[J]. 中草药, 2019, v.50;No.659(24):110-116. 6. 李程程, 左雅敏, 蒋信明,等. 水芹中6种成分同时测定及其指纹图谱建立[J]. 中成药, 2016, 38(012):2621-2625. 7. 谭湘杰, 于福来, 庞玉新,等. 海南裸花紫珠药材中7种成分含量分析[J]. 中国现代中药, 2018, 20(002):173-178. 8. 樊雪艳, 李丹凤, 李石飞,等. 连翘花美白活性有效部位的筛选及其成分分析[J]. 化学研究与应用, 2018, v.30(06):25-30. 9. 赵鑫, 徐保鑫, 张学兰,等. 金银花制炭工艺的优化[J]. 中成药, 2018, 040(002):336-340. 10. 谭湘杰 于福来 黄梅 等. 不同初加工方式对裸花紫珠主要化学成分含量影响[J]. 热带农业科学 2018 v.38;No.251(07):36-42. 11. 黄梅, 于福来, 陈振夏,等. 土壤因子对裸花紫珠有效成分含量的影响研究[J]. 中国药房, 2018(1):2095-2099. 12. 曹健 秦朗 张立国 等. 2种酚类抗氧化剂对牡丹籽油氧化稳定性影响研究[J]. 粮食与油脂 2019 032(012):25-29. 13. 朱伟 赵赫 姚岚 等. UFLC-MS/MS法同时测定肺宁颗粒中6种化学成分[J]. 解放军药学学报 2017(04):356-358. 14. 袁博 贺瑶 郑竟成 田华 何东平.两种天然酚类抗氧化剂对DHA藻油抗氧化作用研究[J].中国食品添加剂 2018(05):122-127. 15. 袁博, 曹健, 秦朗,等. 四种酚类化合物体外抗氧化活性的比较研究[J]. 食品工业, 2018, 39(09):206-210. 16. 王萌, 李小定, 刘硕,等. 有机酸对紫甘薯花色苷的辅色作用[J]. 食品科学, 2014, 35(23):119-124. 17. 夏瑛, 李良, 董孝元,等. 源于解淀粉芽胞杆菌酚酸脱羧酶的克隆与表达[J]. 微生物学通报, 2020(7). 18. 陆杰, 王婷婷, 陈颖,等. 茵陈清筋颗粒质量标准的研究[J]. 中成药, 2020, v.42(06):43-48. 19. 魏萍, 丁月, 鲁群,等. 蜂胶和杨树胶中黄酮类成分及其抑制α-葡萄糖苷酶活性研究[J]. 华中农业大学学报, 2018, 37(003):92-99. 20. 张爽 付士朋 刘悦 等. HPLC法分析刺五加茎中原儿茶酸及苯丙素类成分动态累积规律研究[J]. 天然产物研究与开发 2018(8):1410-1414. 21. 许一鸣 吴啟南 乐巍 等. 不同产地薄荷药材有机酸与黄酮类成分分析[J]. 中药材 2018(2):299-302. 22. 陈梦杰, 李文霞, 李思潼,等. 蒲公英酚类特征成分含量测定及其特征图谱质量表征关联分析[J]. 中国实验方剂学杂志, 2018, 024(016):12-20. 23. 温子帅 刘露露 李新蕊 等. HPLC法同时测定不同产地荆芥中8种成分的含量[J]. 中药材 2019(1). 24. 路俊仙, 吕凌, 张才波. 忍冬4个药用部位中11种化学成分的含量测定[J]. 中药材, 2019(5). 25. 姜万舟, 高平, 杨明德,等. 杏鲍菇乙醇提取物的抗氧化活性及成分分离鉴定[J]. 食品工业科技, 2015, 36(22):87-91. 26. 战妍妃, 李媛媛, 安欣欣,等. 石韦的抗病毒黄酮部位及有效化学成分[J]. 暨南大学学报:自然科学与医学版, 2018, 039(006):470-480. 27. 路俊仙, 吕凌, 张才波. 金银花和灰毡毛忍冬多成分定性的指纹图谱比较[J]. 中华中医药杂志, 2019, 034(007):3215-3219. 28. 周菲, 胡荣, 刘晨杰,等. 不同连翘叶炮制品抑制胰脂肪酶活性比较[J]. 山西大学学报(自然科学版), 2018, v.41;No.160(02):161-167. 29. 郭巧英. 航天诱变SP6代夏枯草生物学性状及其有效成分研究[D]. 西北农林科技大学. 30. 王琬宁, 李兴国, 孙侨冶,等. 红树莓非花色苷酚的提取与鉴定[J]. 北方园艺, 2020, No.457(10):28-37. 31. 肖飞, 彭红, 许静,等. 达立通颗粒的HPLC指纹图谱研究及其LC-MS化学成分分析[J]. 中药材, 2019(4). 32. 王玲娜,苏征,刘星劼,张芳,刘谦,张永清.金银花活性成分与生态因子相关性研究[J].中国实验方剂学杂志,2016,22(17):27-31. 33. 王红梅, 彭璐, 王悦,等. 五个品种葡萄理化特性及酚类物质组成的比较[J]. 食品与发酵工业, 2019, 45(07):78-85. 34. 王玲娜,张芳,李佳,刘红燕,姜秋,张永清.金银花新品种“华金6号”药材品质比较研究[J].中药材,2019,42(09):2030-2035. 35. 潘馨 衷林清 周楚楚 等. HPLC同时测定草珊瑚中9个有效成分的含量[J]. 药物分析杂志 2017 037(007):1207-1214. 36. 苏征 王玲娜 张芳 等. 不同产地忍冬藤HPLC指纹图谱比较研究[J]. 时珍国医国药 2017(05):193-195. 37. 李依娜 邹颖 余元善 肖更生 徐玉娟 邹波.不同酚酸对三华李清汁贮藏期间色泽稳定性的比较分析[J].现代食品科技 2020 36(07):165-172+16. 38. 路东波, 高园园, 姜艳艳,等. 基于有效基准特征图谱质量表征模式的中药紫苏叶质量评价研究[J]. 北京中医药大学学报, 2020, 043(002):148-162. 39. 赵艺楠, 宋科, 彭胜,等. 沸石分子筛吸附分离忽地笑中石蒜碱[J]. 天然产物研究与开发, 2016, 028(002):289-292,299. 40. 苏帆, 薛佳, 杨曦,等. 酚酸对红肉苹果花色苷辅色效果及稳定性的影响[J]. 中国农业科学, 2017(4). 41. 赵志国, 段文娟, 张晓梦,等. HPLC-DAD-ESI-TOF/MS鉴别和测定前列欣胶囊中多种成分及其多指标定量指纹图谱研究[J]. 药物分析杂志, 2017, 037(010):1810-1816. 42. 赵玥, 齐越, 单国顺,等. 不同产地火绒草HPLC指纹图谱的建立及化学模式识别[J]. 中成药, 2019, 041(004):849-854. 43. 朱姮, 于金倩, 刘倩,等. 基于RRLC-DAD-ESI-Q-TOF-MS技术的山东金银花多指标定量指纹图谱分析[J]. 中国实验方剂学杂志, 2017, 023(019):82-89. 44. 邵佩, 陈胜, 罗威,等. 猕猴桃多酚的纯化工艺及组分分析[J]. 食品科技, 2019, v.44;No.338(12):266-271. 45. 赵志国, 井凤, 张敏敏,等. 西藏木瓜HPLC指纹图谱研究及多成分测定[J]. 中草药, 2018, 49(10):239-244. 46. 陈智. 金银花和黄芩不同煎煮方式化学成分变化及抗病毒作用比较[J]. 中华中医药杂志, 2019, v.34(10):129-133. 47. 宋晓芳 范宝磊 曾祥玲 李婷婷 史玉敏 邹晶晶 杨洁 陈洪国.HPLC-MS/MS法同时测定不同桂花品种中7个多酚类活性成分的含量[J].药物分析杂志 2019 39(10):1811-1820. 48. 李俊萍, 付士朋, 王谦博,等. 多指标综合评价刺五加叶适宜采收期的研究[J]. 中草药, 2019, v.50;No.648(13):196-201. 49. 赵玥, 尤献民, 姜鸿,等. 基于UFLC法的辽宁地区火绒草质量评价研究[J]. 沈阳药科大学学报, 2019(6):511-517. 50. 金司阳, 刘寒, 杨立学,等. 植物-土壤反馈对刺五加幼苗次生代谢产物的影响[J]. 中国实验方剂学杂志, 2020. 51. 范琳琳, 王英, 黄自苏,等. 外源添加物质对黑莓清汁花色苷稳定性和抗氧化活性的影响[J]. 食品工业科技, 2019, v.40;No.420(04):62-67. 52. 马云, 王尧尧, 王蕾,等. 忍冬花发育期间形态与13种活性成分含量变化[J]. 中药材, 2018, 041(007):1559-1565. 53. 高振鹏, 宋杨, 张美娜,等. 益生菌发酵苹果汁过程中总酚酸变化与动力学研究[J]. 农业机械学报, 2019, 050(011):350-356. 54. 王玲娜, 孙希芳, 张芳,等. 不同发育时期金银花颜色与活性成分的相关性分析[J]. 中草药, 2017, 15(v.48;No.602):171-177. 55. 郄佩娟, 段旭昌, 王敏,等. 长裂苦苣菜甲醇提取物各极性成分的抗氧化活性研究[J]. 食品工业科技, 2016, 37(16):146-150. 56. 范佳慧, 岳锦萍, 杨蕴格,等. 利用非糖物质快速鉴别单花蜂蜜[J]. 现代食品科技, 2020, v.36;No.246(02):119+269-276. 57. 王婷婷, 苑伟, 李华,等. 复合小浆果果酒中的酚类物质及其抗氧化活性分析[J]. 食品与发酵工业, 2019, 45(03):183-188. 58. 黑青稞麸皮结合态酚类物质大孔树脂分离纯化工艺优化 59. 王奕芳,温承坤,陈茂彬,张玉,李琴,方尚玲.麻城老米酒中酚类物质的初探[J].中国酿造,2019,38(12):175-178. 60. 田莉, 李海萍, 袁亚宏,等. 真空耦合超声波提取苹果渣多酚的工艺优化[J]. 食品科学, 2017(14):240-246. 61. 李诗卉,梁诗瑶,伊美瑾,夏伯候,黄胜,颜冬兰,林丽美.夏枯草茎叶复合菌发酵工艺、成分及活性变化研究[J].时珍国医国药,2020,31(11):2629-2633. 62. 王俊丽,庞克坚,唐辉,袁小红,张虹,郑家耀.蒙药材博格日乐吉根的质量标准研究[J].中国现代应用药学,2020,37(24):2953-2961. 63. 小红,庞克坚,唐辉,张虹,魏沣,刘乐乐,姜国珍.蒙药哈日-沙布嘎(铁杆蒿)的质量标准提升[J].中国药房,2021,32(05):536-541. 64. 王庆卫,刘启玲,崔胜文.不同干燥方式对红枣营养品质及抗氧化活性的影响[J].食品工业,2020,41(12):218-222. 65. 杨文娟,侯旭杰,阿依古丽·吾斯曼,侯文鑫,郭芹,蒲云峰,王强.超声辅助提取花生根多酚工艺优化及组成分析[J].食品研究与开发,2021,42(01):107-111. 66. 刘启玲,王庆卫,崔胜文.不同预处理方式对红枣热风-微波联合干燥品质特性及抗氧化活性的影响[J].食品研究与开发,2020,41(24):124-130. 67. 陆胜波. 铁核桃果实青皮和内种皮芦丁合成的转录组与代谢组分析[D].贵州大学,2020. 68. 冯子芳,费逸明,袁晓航,陈晓伟,胡敏敏,费倩倩.高效液相色谱波长切换法同时测定葆肾合剂中6种成分的含量[J].中南药学,2021,19(01):114-117. 69. 李承浩,王萌,任晓亮.磺化杯6芳烃对4类中药单体成分增溶作用及其机制研究[J].中国现代中药,2020,22(12):2032-2038. 70. 徐芳芳,张秀莉,侯滔,曲腊腊,王纪霞,刘艳芳,梁鑫淼.天然产物中FFA1受体新激动剂的发现与研究[J].上海中医药大学学报,2021,35(01):12-19.[4]宫梦琪,孙倩,李振.天麻中天麻素提取工艺优化及抑制α-葡萄糖苷酶活性研究[J].中国果菜,2020,40(09):14-17+23. 71. 武兴菲.红枣干制过程中酚类物质的变化及其与褐变的关系[J].保鲜与加工,2021,21(03):125-129+135. 72. 杨馨悦,杨宇驰,周秀娟,薛桂新.柑橘果醋发酵条件的优化及其成分分析[J].中国调味品,2020,45(10):75-79. 73. 李栋,薛瑞婷.高温高湿气体冲击处理对中短波红外干制红枣品质的影响[J].食品研究与开发,2020,41(22):107-112. 74. Dong, Qingying, et al. "Comparative study on phenolic compounds, triterpenoids, and antioxidant activity of Ganoderma lucidum affected by different drying methods." Journal of Food Measurement and Characterization 13.4 (2019): 3198-3205.https://doi.org/10. 75. Dong, Qingying, et al. "Comparative study on phenolic compounds, triterpenoids, and antioxidant activity of Ganoderma lucidum affected by different drying methods." Journal of Food Measurement and Characterization 13.4 (2019): 3198-3205.https://doi.org/10. 76. Liu, Huan, et al. "Antimicrobial activity and virulence attenuation of citral against the fish pathogen Vibrio alginolyticus." Aquaculture 515 (2020): 734578.https://doi.org/10.1016/j.aquaculture.2019.734578 77. Zhu, Hao, et al. "Anti-inflammatory effects of p-coumaric acid, a natural compound of Oldenlandia diffusa, on arthritis model rats." Evidence-Based Complementary and Alternative Medicine 2018 (2018).https://doi.org/10.1155/2018/5198594 78. Liao, Yinyin, et al. "Induced biosynthesis of chlorogenic acid in sweetpotato leaves confers the resistance against sweetpotato weevil attack." Journal of advanced research 24 (2020): 513-522.https://doi.org/10.1016/j.jare.2020.06.011 79. Deng, Rui, et al. "Identification of poliumoside metabolites in rat feces by high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry." Journal of Chromatography B 969 (2014): 285-296.https://doi.org/10.1016/j. 80. Liao, Yinyin, et al. "Induced biosynthesis of chlorogenic acid in sweetpotato leaves confers the resistance against sweetpotato weevil attack." Journal of advanced research 24 (2020): 513-522.https://doi.org/10.1016/j.jare.2020.06.011 81. Ahmed, Ishfaq, et al. "Effect of tyrosinase and caffeic acid crosslinking of turbot parvalbumin on the digestibility, and release of mediators and cytokines from activated RBL-2H3 cells." Food chemistry 300 (2019): 125209.https://doi.org/10.1016/j.foodchem 82. Atif, Muhammad Jawaad, et al. "Effect of photoperiod and temperature on garlic (Allium sativum L.) bulbing and selected endogenous chemical factors." Environmental and Experimental Botany 180 (2020): 104250.https://doi.org/10.1016/j.envexpbot.2020.104250 83. Wu, Ya, et al. "Anti‐obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high‐fat‐diet‐induced obese mice." Journal of Food Science 86.1 (2021): 215-227. 84. Tian, Dong, et al. "Characterization of Farfarae Flos by proton nuclear magnetic resonance fingerprinting and chemometrics." Analytical Letters 48.1 (2015): 127-136.https://doi.org/10.1080/00032719.2014.936018 85. Hengqiang Zhao, Minmin Zhang, Qian Liu, Xiaoli Wang, Ruixuan Zhao, Yanling Geng, Tityee Wong, Shengbo Li & Xiao Wang (2018) A comprehensive screening shows that ergothioneine is the most abundant antioxidant in the wild macrofungus Phylloporia ribis Ryvard 86. Bao, Tao, et al. "Cold plasma: An emerging pretreatment technology for the drying of jujube slices." Food Chemistry 337 (2021): 127783.https://doi.org/10.1016/j.foodchem.2020.127783 87. Cai, Ming, et al. "Changes in physicochemical profiles and quality of apple juice treated by ultrafiltration and during its storage." Food science & nutrition 8.6 (2020): 2913-2919.https://doi.org/10.1002/fsn3.1593 88. Wang, Jixia, et al. "Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay." RSC Advances 5.33 (2015): 25768-25776.https://doi.org/10.1039/C4RA16102E 89. Wei, Yulong, et al. "Exploring the biochemical properties of three polyphenol oxidases from blueberry (Vaccinium corymbosum L.)." Food Chemistry 344 (2021): 128678.https://doi.org/10.1016/j.foodchem.2020.128678 90. Cai, Z, Liao, H, Wang, C, et al. A comprehensive study of the aerial parts of Lonicera japonica Thunb. based on metabolite profiling coupled with PLS-DA. Phytochemical Analysis. 2020; 31: 786– 800. https://doi.org/10.1002/pca.2943 91. Deng, Junlin, et al. "Comparative evaluation of maceration and ultrasonic-assisted extraction of phenolic compounds from fresh olives." Ultrasonics Sonochemistry 37 (2017): 328-334.https://doi.org/10.1016/j.ultsonch.2017.01.023 92. Hengqiang Zhao, Minmin Zhang, Qian Liu, Xiaoli Wang, Ruixuan Zhao, Yanling Geng, Tityee Wong, Shengbo Li & Xiao Wang (2018) A comprehensive screening shows that ergothioneine is the most abundant antioxidant in the wild macrofungus Phylloporia ribis Ryvard 93. Chen, Yazhen, et al. "Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame." Food and Chemical Toxicology 139 (2020): 111239.https://doi.org/10.1016/j.fct.2020.111239 94. Nan, Xingmei, et al. "Bioactive fraction of Rhodiola algida against chronic hypoxia-induced pulmonary arterial hypertension and its anti-proliferation mechanism in rats." Journal of ethnopharmacology 216 (2018): 175-183.https://doi.org/10.1016/j.jep.2018.0 95. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera 96. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera 97. [IF=7.514] Huipin Li et al."Enrichment of antioxidants from soy sauce using macroporous resin and identification of 4-ethylguaiacol, catechol, daidzein, and 4-ethylphenol as key small molecule antioxidants in soy sauce."Food Chem. 2018 Feb;240:885 98. [IF=7.491] Junlin Deng et al."Comparative evaluation of maceration and ultrasonic-assisted extraction of phenolic compounds from fresh olives."Ultrason Sonochem. 2017 Jul;37:328 99. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606 100. [IF=5.645] Jun Lu et al."Phenolic composition, antioxidant, antibacterial and anti-inflammatory activities of leaf and stem extracts from Cryptotaenia japonica Hassk."Ind Crop Prod. 2018 Oct;122:522 101. [IF=5.279] Yingying Wei et al."Hot Air Treatment Induces Disease Resistance through Activating the Phenylpropanoid Metabolism in Cherry Tomato Fruit."J Agr Food Chem. 2017;65(36):8003–8010 102. [IF=4.411] Ying Zhang et al."Compounds Identification in Semen Cuscutae by Ultra-High-Performance Liquid Chromatography (UPLCs) Coupled to Electrospray Ionization Mass Spectrometry."Molecules. 2018 May;23(5):1199 103. [IF=3.757] Yuchen Wang et al."Metabolic profile of ginkgo kernel juice fermented with lactic aicd bacteria: A potential way to degrade ginkgolic acids and enrich terpene lactones and phenolics."Process Biochem. 2019 Jan;76:25 104. [IF=3.638] Jia Xue et al."Enhanced stability of red-fleshed apple anthocyanins by copigmentation and encapsulation."J Sci Food Agr. 2019 May;99(7):3381-3390 105. [IF=3.223] Yanli Zhang et al."Electrochemical Behavior of Caffeic Acid Assayed with Gold Nanoparticles/Graphene Nanosheets Modified Glassy Carbon Electrode."Electroanal. 2013 May;25(5):1230-1236 106. [IF=3.205] Rui Deng et al."Identification of poliumoside metabolites in rat feces by high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry."J Chromatogr B. 2014 Oct;969:285 107. [IF=3.049] Jixia Wang et al."Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay."Rsc Adv. 2015 Mar;5(33):25768-25776 108. [IF=3.046] Menglin Wei et al."Protective effects of a Chotosan Fraction and its active components on β-amyloid-induced neurotoxicity."Neurosci Lett. 2016 Mar;617:143 109. [IF=2.329] Dong Tian et al."Characterization of Farfarae Flos by Proton Nuclear Magnetic Resonance Fingerprinting and Chemometrics."Anal Lett. 2015;48(1):127-136 110. [IF=1.984] Zhu Hao et al."Anti-Inflammatory Effects of the Bioactive Compound Ferulic Acid Contained in Oldenlandia diffusa on Collagen-Induced Arthritis in Rats."Evid-Based Compl Alt. 2014;2014:573801 111. [IF=1.984] Zhu Hao et al."Anti-Inflammatory Effects of p-Coumaric Acid, a Natural Compound of Oldenlandia diffusa, on Arthritis Model Rats."Evid-Based Compl Alt. 2018;2018:5198594 112. [IF=1.902] Yining Zhao et al."Simultaneous quantitation of 23 bioactive compounds in Tanreqing capsule by high-performance liquid chromatography electrospray ionization tandem mass spectrometry."Biomed Chromatogr. 2019 Jul;33(7):e4531 113. [IF=13.273] Qingqing Zhou et al."Polydopamine-induced growth of mineralized γ-FeOOH nanorods for construction of silk fabric with excellent superhydrophobicity, flame retardancy and UV resistance."Chem Eng J. 2020 Feb;382:122988 114. [IF=10.479] Yinyin Liao et al."Induced biosynthesis of chlorogenic acid in sweetpotato leaves confers the resistance against sweetpotato weevil attack."J Adv Res. 2020 Jul;24:513 115. [IF=7.514] Xuehua Wang et al."Non-volatile and volatile metabolic profiling of tomato juice processed by high-hydrostatic-pressure and high-temperature short-time."Food Chem. 2022 Mar;371:131161 116. [IF=7.514] Yi Song et al."Caffeoyl substitution decreased the binding and inhibitory activity of quinic acid against α-amylase: The reason why chlorogenic acid is a relatively weak enzyme inhibitor."Food Chem. 2022 Mar;371:131278 117. [IF=7.514] Jinxue Hou et al."Variations in phenolic acids and antioxidant activity of navel orange at different growth stages."Food Chem. 2021 Oct;360:129980 118. [IF=7.514] Hongcai Li et al."Study on the nutritional characteristics and antioxidant activity of dealcoholized sequentially fermented apple juice with Saccharomyces cerevisiae and Lactobacillus plantarum fermentation."Food Chem. 2021 Nov;363:130351 119. [IF=7.514] Tao Bao et al."Cold plasma: An emerging pretreatment technology for the drying of jujube slices."Food Chem. 2021 Feb;337:127783 120. [IF=7.514] Xiaoming Yu et al."Impact of processing technologies on isoflavones, phenolic acids, and antioxidant capacities of soymilk prepared from 15 soybean varieties."Food Chem. 2021 May;345:128612 121. [IF=6.986] Qingqing Song et al."Retention Time and Optimal Collision Energy Advance Structural Annotation Relied on LC–MS/MS: An Application in Metabolite Identification of an Antidementia Agent Namely Echinacoside."Anal Chem. 2019;91(23):15040–15048 122. [IF=6.576] Wenyue Li et al."Both Acidic pH Value and Binding Interactions of Tartaric Acid With α-Glucosidase Cause the Enzyme Inhibition: The Mechanism in α-Glucosidase Inhibition of Four Caffeic and Tartaric Acid Derivates."Front Nutr. 2021; 8: 766756 123. [IF=6.475] Yuge Guan et al."Proteomic analysis validates previous findings on wounding-responsive plant hormone signaling and primary metabolism contributing to the biosynthesis of secondary metabolites based on metabolomic analysis in harvested broccoli (Brassica o 124. [IF=6.306] Yunke Huang et al."Ex vivo to in vivo extrapolation of syringic acid and ferulic acid as grape juice proxies for endothelium-dependent vasodilation: Redefining vasoprotective resveratrol of the French paradox."Food Chem. 2021 Jun;:130323 125. [IF=6.023] Yazhen Chen et al."Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame."Food Chem Toxicol. 2020 May;139:111239 126. [IF=5.81] Chenning Zhang et al."Global Analysis the Potential Medicinal Substances of Shuangxia Decoction and the Process In Vivo via Mass Spectrometry Technology."Front Pharmacol. 2021; 12: 654807 127. [IF=5.81] Zhao Jing et al."Intra-Herb Interactions: Primary Metabolites in Coptidis Rhizoma Extract Improved the Pharmacokinetics of Oral Berberine Hydrochloride in Mice."Front Pharmacol. 2021 Jun;0:1426 128. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro 129. [IF=5.64] Zhang Yuxiang et al."Structure-Dependent Inhibition of Stenotrophomonas maltophilia by Polyphenol and Its Impact on Cell Membrane."Front Microbiol. 2019 Nov;0:2646 130. [IF=5.64] Ji Xuemeng et al."Function Characterization of Endogenous Plasmids in Cronobacter sakazakii and Identification of p-Coumaric Acid as Plasmid-Curing Agent."Front Microbiol. 2021 Jun;0:1589 131. [IF=5.537] Yi Wang et al."Reactive oxygen species-mediated the accumulation of suberin polyphenolics and lignin at wound sites on muskmelons elicited by benzo (1, 2, 3)-thiadiazole-7-carbothioic acid S-methyl ester."Postharvest Biol Tec. 2020 Dec;170:111325 132. [IF=5.455] Lu Lan et al."Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa."Chin Med-Uk. 2021 Dec;16(1):1-17 133. [IF=5.396] Ruihong Dong et al."Release and metabolism of bound polyphenols from carrot dietary fiber and their potential activity in in vitro digestion and colonic fermentation."Food Funct. 2020 Jul;11(7):6652-6665 134. [IF=5.277] Jianping Wei et al."Assessment of chemical composition and sensorial properties of ciders fermented with different non-Saccharomyces yeasts in pure and mixed fermentations."Int J Food Microbiol. 2020 Apr;318:108471 135. [IF=4.952] Ting Zhao et al."The antioxidant property and α-amylase inhibition activity of young apple polyphenols are related with apple varieties."Lwt Food Sci Technol. 2019 Aug;111:252 136. [IF=4.952] Yuan Yuan et al."Diversity of phenolics including hydroxycinnamic acid amide derivatives, phenolic acids contribute to antioxidant properties of proso millet."Lwt Food Sci Technol. 2022 Jan;154:112611 137. [IF=4.952] Jia Xue et al."Contrasting microbiomes of raw and ripened Pu-erh tea associated with distinct chemical profiles."Lwt Food Sci Technol. 2020 Apr;124:109147 138. [IF=4.952] Yuting Zheng et al."Antioxidant, α-amylase and α-glucosidase inhibitory activities of bound polyphenols extracted from mung bean skin dietary fiber."Lwt Food Sci Technol. 2020 Oct;132:109943 139. [IF=4.952] Fangting Bai et al."Caffeoyl substitution changes the inhibition mode of tartaric acid against α-amylase: Analysis of the enzyme inhibition by four caffeic and tartaric acid derivates."Lwt Food Sci Technol. 2020 Nov;133:109942 140. [IF=4.952] Shuxin Tang et al."Effect of Lactobacillus plantarum-fermented mulberry pomace on antioxidant properties and fecal microbial community."Lwt Food Sci Technol. 2021 Jul;147:111651 141. [IF=4.952] Guanyi Peng et al."Combined microwave and enzymatic treatment improve the release of insoluble bound phenolic compounds from the grapefruit peel insoluble dietary fiber."Lwt Food Sci Technol. 2021 Sep;149:111905 142. [IF=4.952] Yuxin Hao et al."Stability and mechanism of phenolic compounds from raspberry extract under in vitro gastrointestinal digestion."Lwt Food Sci Technol. 2021 Mar;139:110552 143. [IF=4.932] Dandan Wang et al."Simultaneous Quantification of Trace and Micro Phenolic Compounds by Liquid Chromatography Tandem-Mass Spectrometry."Metabolites. 2021 Sep;11(9):589 144. [IF=4.879] Yang Liu et al."UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings."Biomolecules. 2020 Apr;10(4):504 145. [IF=4.821] Xiangwei Chang et al."Untargeted metabolomics approach reveals the tissue-specific markers of balloon flower root (Platycodi Radix) using UPLC-Q-TOF/MS."Microchem J. 2021 Sep;168:106447 146. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460 147. [IF=4.411] Shengxin Yin et al."Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot."Molecules. 2021 Jan;26(7):1864 148. [IF=4.411] Min Li et al."Study of the Variation of Phenolic Acid and Flavonoid Content from Fresh Artemisiae argyi Folium to Moxa Wool."Molecules. 2019 Jan;24(24):4603 149. [IF=4.411] Liqing Yin et al."Neuroprotective Potency of Tofu Bio-Processed Using Actinomucor elegans against Hypoxic Injury Induced by Cobalt Chloride in PC12 Cells."Molecules. 2021 Jan;26(10):2983 150. [IF=4.411] Fang Sheng et al."The Analysis of Phenolic Compounds in Walnut Husk and Pellicle by UPLC-Q-Orbitrap HRMS and HPLC."Molecules. 2021 Jan;26(10):3013 151. [IF=4.379] Zhang Liang-Liang et al."Chemical composition, antibacterial activity and action mechanism of different extracts from hawthorn (Crataegus pinnatifida Bge.)."Sci Rep-Uk. 2020 Jun;10(1):1-13 152. [IF=4.24] Nana Li et al."Characterization of phenolic compounds and anti-acetylcholinase activity of coconut shells."Food Biosci. 2021 Aug;42:101204 153. [IF=4.142] Lei Huibo et al."Comprehensive profiling of the chemical components and potential markers in raw and processed Cistanche tubulosa by combining ultra-high-performance liquid chromatography coupled with tandem mass spectrometry and MS/MS-based molecular ne 154. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4 155. [IF=3.978] Chen-Hui Zhao et al."Engineering budding yeast for the production of coumarins from lignin."Biochem Eng J. 2020 Aug;160:107634 156. [IF=3.935] Jingyun Zheng et al."A systematic investigation on free phenolic acids and flavonoids profiles of commonly consumed edible flowers in China."J Pharmaceut Biomed. 2019 Aug;172:268 157. [IF=3.935] Hengqiang Zhao et al."An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicerae Japonicae."J Pharmaceut Biomed. 2019 Oct;175:112758 158. [IF=3.645] Jie Lu et al."Identification and determination of chemical constituents from Yinchen Qingjin granules by ultra high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry."J Sep Sci. 2021 Apr;44(7):1324-1344 159. [IF=3.638] Tao Bao et al."Green alternative methods for pretreatment of whole jujube before the drying process."Journal Of The Science Of Food And Agriculture. 2021 Aug 11 160. [IF=3.616] Meng Zhang et al."Comparative evaluation on phenolic profiles, antioxidant properties and α-glucosidase inhibitory effects of different milling fractions of foxtail millet."J Cereal Sci. 2021 May;99:103217 161. [IF=3.512] Yahong Chen et al."Identification of Potential Human Ryanodine Receptor 1 Agonists and Molecular Mechanisms of Natural Small-Molecule Phenols as Anxiolytics."Acs Omega. 2021;XXXX(XXX):XXX-XXX 162. [IF=3.411] Shi Guiqin et al."UPLC-ESI-MS/MS Analysis and Evaluation of Antioxidant Activity of Total Flavonoid Extract from Paeonia lactiflora Seed Peel and Optimization by Response Surface Methodology (RSM)."Biomed Res Int. 2021;2021:7304107 163. [IF=3.373] Zhichen Cai et al."A comprehensive study of the aerial parts of Lonicera japonica Thunb. based on metabolite profiling coupled with PLS-DA."Phytochem Analysis. 2020 Nov;31(6):786-800 164. [IF=3.24] Zhichen Cai et al."Metabolomics characterizes the metabolic changes of Lonicerae Japonicae Flos under different salt stresses."Plos One. 2020 Dec;15(12):e0243111 165. [IF=3.167] Ya Wu et al."Anti-obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high-fat-diet-induced obese mice."J Food Sci. 2021 Jan;86(1):215-227 166. [IF=3] Yong-Shen REN et al."Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity in mice via activation of the Nrf-2/HO-1 pathway and inhibition of the JNK signaling pathway."Chin J Nat Medicines. 2020 Feb;18:103 167. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 168. [IF=2.863] Jie Hu et al."Tracking the dynamic changes of a flavor, phenolic profile, and antioxidant properties of Lactiplantibacillus plantarum- and Saccharomyces cerevisiae-fermented mulberry wine."Food Sci Nutr. 2021 Nov;9(11):6294-6306 169. [IF=2.863] Ming Cai et al."Changes in physicochemical profiles and quality of apple juice treated by ultrafiltration and during its storage."Food Sci Nutr. 2020 Jun;8(6):2913-2919 170. [IF=2.863] Qiaoran Zheng et al."Optimizing synchronous extraction and antioxidant activity evaluation of polyphenols and polysaccharides from Ya'an Tibetan tea (Camellia sinensis)."Food Sci Nutr. 2020 Jan;8(1):489-499 171. [IF=2.727] Yanlei Zhang et al."Active components and antioxidant activity of thirty-seven varieties of Chinese jujube fruits (Ziziphus jujuba Mill.)."Int J Food Prop. 2021;24(1):1479-1494 172. [IF=2.72] Wenfeng Li et al."Citric acid-enhanced dissolution of polyphenols during soaking of different teas."J Food Biochem. 2019 Dec;43(12):e13046 173. [IF=2.478] Kun Li et al."Composition, Antivirulence Activity, and Active Property Distribution of the Fruit of Terminalia chebula Retz."J Food Sci. 2019 Jul;84(7):1721-1729 174. [IF=2.431] Dong Qingying et al."Comparative study on phenolic compounds, triterpenoids, and antioxidant activity of Ganoderma lucidum affected by different drying methods."J Food Meas Charact. 2019 Dec;13(4):3198-3205 175. [IF=2.352] Luo Ting et al."Phytochemical composition and potential biological activities assessment of raspberry leaf extracts from nine different raspberry species and raspberry leaf tea."J Berry Res. 2020 Jan;10(2):295-309 176. [IF=1.902] Ting Zhang et al."The influence of essential oils from ZhaLi NuSi Prescription on the pharmacokinetics of its non-volatile components in normal rats."Biomedical Chromatography. 2021 Oct 21 177. [IF=1.902] Hongyan Liu et al."Spectrum–effect relationship study between HPLC fingerprints and antioxidant of honeysuckle extract."Biomed Chromatogr. 2019 Oct;33(10):e4583 178. [IF=1.813] Zhang Ying et al."Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen."Evid-Based Compl Alt. 2019;2019:2049497 179. [IF=1.77] Muhammad Khalid et al."Suppression of clubroot (Plasmodiophora brassicae) development in Brassica campestris sp. chinensis L. via exogenous inoculation of Piriformospora indica."J Radiat Res Appl Sc. 2020;13(1):180-190 180. [IF=1.312] Tie-xin Tang et al."A pattern recognition method on smartphones for planar chromatography and verification on chromatograms of four herbal medicines from citrus fruits."Journal Of Liquid Chromatography & Related Technologies. 2021 Aug 26 181. [IF=1.296] Han Meiling et al."Analysis of flavonoids and anthocyanin biosynthesis-related genes expression reveals the mechanism of petal color fading of Malus hupehensis (Rosaceae)."Braz J Bot. 2020 Mar;43(1):81-89 182. [IF=1.729] Zhang Mengyu et al."The effects of caffeic acid and epicatechin treatment on gray mold resistance and antioxidant metabolism in apples."J Plant Pathol. 2022 Mar;:1-10 183. [IF=3.645] Shuo Gu et al."Develop a stepwise integrated method to screen biomarkers of Baihe-Dihuang Tang on the treatment of depression in rats applying with composition screened, untargeted, and targeted metabolomics analysis."Journal Of Separation Science. 2022 M 184. [IF=6.475] Jinxin Li et al."Trapping of reactive carbonyl species by fiber-bound polyphenols from whole grains under simulated physiological conditions."Food Res Int. 2022 Jun;156:111142 185. [IF=4.215] Ma Junqing et al."Mycorrhizal symbiosis promotes the nutrient content accumulation and affects the root exudates in maize."Bmc Plant Biol. 2022 Dec;22(1):1-13 186. [IF=6.475] Guoping Lai et al."Free, soluble conjugated and insoluble bonded phenolic acids in Keemun black tea: From UPLC-QQQ-MS/MS method development to chemical shifts monitoring during processing."Food Res Int. 2022 May;155:111041 187. [IF=6.576] Jie Yang et al."Fermentation and Storage Characteristics of “Fuji” Apple Juice Using Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum: Microbial Growth, Metabolism of Bioactives and in vitro Bioactivities."Front Nutr. 2022; 9: 83 188. [IF=5.396] Jie Li et al."Cryptochlorogenic acid and its metabolites ameliorate myocardial hypertrophy through a HIF1α-related pathway."Food Funct. 2022 Jan;: 189. [IF=7.514] Wenjing Liu et al."Quality structural annotation for the metabolites of chlorogenic acid in rat."Food Chem. 2022 Jan;:132134 190. [IF=5.396] Mengxue He et al."Influence of extraction technology on rapeseed oil functional quality: a study on rapeseed polyphenols."Food Funct. 2021 Dec;: 191. [IF=9.078] Jun Qian et al."A strategy for effective recovery of salvianolic acid a from Salvia miltiorrhiza (Danshen) through multiple interactions."Compos Part B-Eng. 2022 Feb;231:109563 192. [IF=2.331] Shengxin Yin et al."Comparative Study on Chemical Constituents of Medicinal and Non-Medicinal Parts of Flos Abelmoschus manihot, Based on Metabolite Profiling Coupled with Multivariate Statistical Analysis."Horticulturae. 2022 Apr;8(4):317 193. [IF=4.35] Xi Chen et al."Comparison and Optimization of Different Extraction Methods of Bound Phenolics from Jizi439 Black Wheat Bran."Foods. 2022 Jan;11(10):1478 194. [IF=5.154] Ying Jiang et al."Isolation of a novel characterized Issatchenkia terricola from red raspberry fruits on the degradation of citric acid and enrichment of flavonoid and volatile profiles in fermented red raspberry juice."Food Science and Human Wellness. 202 195. [IF=6.475] Zhen Wu et al."How steaming and drying processes affect the active compounds and antioxidant types of Gastrodia elata Bl. f. glauca S. chow."FOOD RESEARCH INTERNATIONAL. 2022 Jul;157:111277 196. [IF=4.952] Wenyue Yu et al."Insight into the characteristics of cider fermented by single and co-culture with Saccharomyces cerevisiae and Schizosaccharomyces pombe based on metabolomic and transcriptomic approaches."LWT-FOOD SCIENCE AND TECHNOLOGY. 2022 Jun;163:1135 197. [IF=4.952] Yu Zhu et al."Comparison of the rheological behavior of composite gels containing potato starch and enzyme-modified potato protein."LWT-FOOD SCIENCE AND TECHNOLOGY. 2022 May;:113610 198. [IF=3.361] Jia Cheng et al."A new method for simultaneous determination of 14 phenolic acids in agricultural soils by multiwavelength HPLC-PDA analysis."RSC Advances. 2022 May;12(23):14939-14944 199. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 200. [IF=6.576] Yingchun Jin et al."Characteristics of Mulberry Leaf Powder Enriched With γ-Aminobutyric Acid and Its Antioxidant Capacity as a Potential Functional Food Ingredient."Frontiers in Nutrition. 2022; 9: 900718 201. [IF=6.475] Yang Zhang et al."Effect of geographical location and soil fertility on main phenolic compounds and fatty acids compositions of virgin olive oil from Leccino cultivar in China."Food Res Int. 2022 Jul;157:111207 202. [IF=3.713] Ren Li et al."Effects of germination time on phenolics, antioxidant capacity, in vitro phenolic bioaccessibility and starch digestibility in sorghum."INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY 203. [IF=3.167] Yanan Xu et al."Covalent modification of zein with polyphenols: A feasible strategy to improve antioxidant activity and solubility."JOURNAL OF FOOD SCIENCE 204. [IF=3.645] Lewen Xiong et al."Study on phenolic acids of Lonicerae japonicae Flos based on ultrahigh performance liquid chromatography-tandem mass spectrometry combined with multivariate statistical analysis."JOURNAL OF SEPARATION SCIENCE 205. [IF=6.057] Supan Cheng et al."Liquid crystal-based sensitive and selective detection of uric acid and uricase in body fluids."Talanta. 2022 Jul;244:123455 |
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