头孢布烯二水合物

中文名	头孢布烯二水合物
英文名	Ceftibuten dihydrate
别名	孢布烯二水合物头孢布烯二水合物头孢布烯二水化合物头孢布坦(头孢布烯) 头孢布烯(头孢布坦) (6R,7R)-7-((Z)-2-(2-氨基噻唑-4-基)-4-羧基丁-2-烯酰胺基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸二水合物 (+)-(6R,7R)-7-[2-(2-氨基-1,3-噻唑-4-基)-4-羧基-2-丁烯酰胺]]-8-氧-5-硫-1-氮双环[4.2.0]辛-2-烯-2-羧酸二水物
英文别名	Cetb Cedax Sch-39720 Cedax (tn) CEDAX DIHYDRATE Cedax dihydrate Ceftibuten (jp15) Sch-39720 dihydrate SCH-39720 DIHYDRATE Ceftibuten dihydrate (+)-(6r,7r)-7-[2-(2-amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate (+)-(6R,7R)-7-[2-(2-Amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate
CAS	118081-34-8
化学式	C15H14N4O6S2.2H2O
分子量	446.459
InChI	InChI=1/C15H14N4O6S2.2H2O/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19;;/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25);2*1H2/b6-1-;;/t10-,13-;;/m1../s1
熔点	>180°C (dec.)
沸点	966.4°C at 760 mmHg
闪点	538.3°C
蒸汽压	0mmHg at 25°C
溶解度	DMSO (微溶) 、水 (微溶)
存储条件	Keep in dark place,Sealed in dry,2-8°C
稳定性	吸湿性
外观	固体
颜色	Pale Yellow to Light Orange
体外研究	Ceftibuten (Sch39720) is highly active against Haemophilus influenza , Escherichia coli , Klebsiella sp., and Proteus sp. and moderately active against Serratia sp. and Streptococcus pyogenes . Ceftibuten is relatively inactive against enterococci and staphylococci and is only weakly active against Pseudomonas aeruginosa and obligate anaerobes. It is also stable in the presence of most β-lactamase-producing organisms except β Bacteroides fragilis . Ceftibuten is very active against strains of the family Enterobacteriaceae (mean MIC for 90% of strains=0.25 μg/ml) but less active against Campylobacterjejuni (mean MIC for 90% of strains=16.0 μg/ml).
体内研究	Ceftibuten, a biologically stableβ-lactam antibiotic, has been shown to be transported by the small peptide transport system, to have relatively high affinity for the carrier and to show clear stereoselective and proton-gradient dependent transport characteristics in rat intestinal brush-border membrane vesicles.

头孢布烯二水合物 - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	2.24 ml	11.199 ml	22.399 ml
5 mM	0.448 ml	2.24 ml	4.48 ml
10 mM	0.224 ml	1.12 ml	2.24 ml
5 mM	0.045 ml	0.224 ml	0.448 ml

最后更新：2024-01-02 23:10:35

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产品名: Ceftibuten(dihydrate);头孢布烯二水合物去供应商网站查看询盘
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