中文名 | 异麦角甾苷 |
英文名 | Isoacteoside |
别名 | 异麦角甾苷 异类叶升麻苷 异毛蕊花糖苷 异洋丁香酚苷 异毛蕊花糖苷(标准品) 异类叶升麻苷(异麦角甾苷) 异类叶升麻苷(异麦角甾苷,异毛蕊花糖苷) |
英文别名 | Isoacteosid ISOACTEOSIDE Isokusaginin Isoacteoside ISOVERBASCOSIDE 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-6-O-[(E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-β-D-glucopyranoside β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-6-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside beta-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-, 6-(3-(3,4-dihydroxyphenyl)-2-propenoate), (E)- ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-2-C-(3,4-dihydroxyphenyl)-6-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside [(2R,3R,4S,5R,6R)-5-(3,4-Dihydroxyphenyl)-6-ethoxy-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
CAS | 61303-13-7 |
化学式 | C29H36O15 |
分子量 | 624.59 |
InChI | InChI=1/C29H36O15/c1-13-22(35)24(37)25(38)29(42-13)44-27-23(36)20(12-41-21(34)7-4-14-2-5-16(30)18(32)10-14)43-28(26(27)39)40-9-8-15-3-6-17(31)19(33)11-15/h2-7,10-11,13,20,22-33,35-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27-,28+,29-/m0/s1 |
密度 | 1.60±0.1 g/cm3(Predicted) |
熔点 | 220~230℃ |
沸点 | 942.9±65.0 °C(Predicted) |
比旋光度 | -52.3 (c, 0.58 in MeOH) |
闪点 | 306.1°C |
蒸汽压 | 0mmHg at 25°C |
溶解度 | 可溶于乙醇、甲醇、醋酸乙酯、DMSO,不溶于石油醚等溶剂。 |
折射率 | 1.689 |
酸度系数 | 9.32±0.10(Predicted) |
存储条件 | under inert gas (nitrogen or Argon) at 2-8°C |
敏感性 | Easily absorbing moisture |
外观 | 白色结晶 |
物化性质 | 白色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于肉苁蓉,地黄。 |
MDL号 | MFCD06798947 |
海关编号 | 29389090 |
参考资料 展开查看 | 1. 毕丹, 张水英, 任晋,等. 超高效液相色谱法同时测定广藿香中6个成分的含量[J]. 药物分析杂志, 2018, 038(008):1331-1336. 2. 刘树民 张帅男 张宁 等. 刺五加潜在靶点网络辅助活性成分效应的发现[J]. 中药药理与临床 2017(05):127-132. 3. 谭湘杰, 于福来, 庞玉新,等. 海南裸花紫珠药材中7种成分含量分析[J]. 中国现代中药, 2018, 20(002):173-178. 4. 黄梅, 于福来, 陈振夏,等. 土壤因子对裸花紫珠有效成分含量的影响研究[J]. 中国药房, 2018(1):2095-2099. 5. 余娜,唐林,谢壮鑫,周厚元,唐皓,李顺祥,朱克俭.臭牡丹不同提取物的抗肿瘤活性筛选及其对裸鼠移植瘤中EMT相关蛋白的影响[J].中药药理与临床,2020,36(04):124-131. 6. Deng, Rui, et al. "Identification of poliumoside metabolites in rat feces by high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry." Journal of Chromatography B 969 (2014): 285-296.https://doi.org/10.1016/j. 7. [IF=5.279] Yirong Jiang et al."Phenylethanoid Glycoside Profiles and Antioxidant Activities of Osmanthus fragrans Lour. Flowers by UPLC/PDA/MS and Simulated Digestion Model."J Agr Food Chem. 2016;64(12):2459–2466 8. [IF=4.556] Maiquan Li et al."Neuroprotective Effects of Four Phenylethanoid Glycosides on H2O2-Induced Apoptosis on PC12 Cells via the Nrf2/ARE Pathway."Int J Mol Sci. 2018 Apr;19(4):1135 9. [IF=4.379] Zhou Fei et al."Degradation of phenylethanoid glycosides in Osmanthus fragrans Lour. flowers and its effect on anti-hypoxia activity."Sci Rep-Uk. 2017 Aug;7(1):1-10 10. [IF=3.205] Rui Deng et al."Identification of poliumoside metabolites in rat feces by high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry."J Chromatogr B. 2014 Oct;969:285 11. [IF=2.629] Zhang Ying et al."The Difference of Chemical Components and Biological Activities of the Raw Products slices and the Wine Steam-Processed Product from Cistanche deserticola."Evid-Based Compl Alt. 2019;2019:2167947 12. [IF=6.558] Qingqing Song et al."Binary code, a flexible tool for diagnostic metabolite sequencing of medicinal plants."Anal Chim Acta. 2019 Dec;1088:89 13. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625 14. [IF=4.142] Lei Huibo et al."Comprehensive profiling of the chemical components and potential markers in raw and processed Cistanche tubulosa by combining ultra-high-performance liquid chromatography coupled with tandem mass spectrometry and MS/MS-based molecular ne 15. [IF=3.935] Yong-Sheng Wu et al."Chemical profiling of Callicarpa nudiflora and its effective compounds identification by compound-target network analysis."J Pharmaceut Biomed. 2020 Apr;182:113110 16. [IF=1.134] Ting-Ting ZHANG et al."Construction of ERGO film modified electrode and its combination with HPLC in determination of five active components in Osmanthus fragrans fruits."CHINESE JOURNAL OF ANALYTICAL CHEMISTRY. 2022 Jul;50:100109 |
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