栀子苷作用
栀子苷(gardenoside)
CAS: 24512-62-7
化学式: C17H24O11
| 中文名 | 栀子苷 |
| 英文名 | gardenoside |
| 别名 | 栀子甙 栀子苷 栀子苷作用 栀子苷用途 山栀子苷B 栀子苷价格 异栀子苷(羟异栀子苷) 异栀子苷(羟异栀子苷,山栀子苷B) |
| 英文别名 | NSC 325664 gardenoside GARDENOSIDE GARDENOSIDE hplc Gardenoside 24512-62-7 Cyclopenta[c]pyran-4-carboxylicacid, 1-(β-D- glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-,methyl ester, (1S,4aS,7S,7aS)- methyl 1-(hexopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate methyl (1S,4aS,7S,7aS)-1-(hexopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate 1α-(β-D-Glucopyranosyloxy)-1,4aα,7,7aα-tetrahydro-7α-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid methyl ester (1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,7,7aα-tetrahydro-7α-hydroxy-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester methyl (1S,4aS,7S,7aS)-1-(beta-D-glucopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate Cyclopenta(c)pyran-4-carboxylic acid, 1-(beta-D-glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-, methyl ester, (1S-(1alpha,4aalpha,7alpha,7aalpha))- |
| CAS | 24512-62-7 |
| 化学式 | C17H24O11 |
| 分子量 | 404.37 |
| InChI | InChI=1/C17H24O11/c1-25-14(23)8-5-26-15(10-7(8)2-3-17(10,24)6-19)28-16-13(22)12(21)11(20)9(4-18)27-16/h2-3,5,7,9-13,15-16,18-22,24H,4,6H2,1H3/t7-,9-,10-,11-,12+,13-,15+,16+,17-/m1/s1 |
| 密度 | 1.61±0.1 g/cm3(Predicted) |
| 熔点 | 118～120℃ |
| 沸点 | 672.8±55.0 °C(Predicted) |
| 比旋光度 | -100.8 (MeOH) |
| 闪点 | 242.1°C |
| 蒸汽压 | 5.53E-21mmHg at 25°C |
| 溶解度 | DMSO (微溶) 、甲醇 (微溶) |
| 折射率 | 1.643 |
| 酸度系数 | 12.28±0.60(Predicted) |
| 存储条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 稳定性 | 吸湿性 |
| 敏感性 | Easily absorbing moisture |
| 外观 | 固体 |
| 颜色 | White to Off-White |
| 物化性质 | 可溶于甲醇、乙醇、DMSO等有机溶剂。 |
| MDL号 | MFCD00017727 |
| 参考资料 展开查看 | 1. 肖日传, 罗光明, 董丽华,等. 基于多波长HPLC-DAD比较栀子不同部位化学成分差异[J]. 中国中药杂志, 2017, 42(23):200-204. 2. Wang, Lu, et al. "Characterization of interaction property of multi‐components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry." Rapid Communications in Mass Spectrometry 30 (2 3. Wang, Lu, et al. "Characterization of interaction property of multi‐components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry." Rapid Communications in Mass Spectrometry 30 (2 4. [IF=6.799] Yun Tang et al."Quantifying orientational regeneration of injured neurons by natural product concentration gradients in a 3D microfluidic device."Lab Chip. 2018 Mar;18(6):971-978 5. [IF=4.759] Lu Wang et al."A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectr 6. [IF=2.419] Lu Wang et al."Characterization of interaction property of multi-components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry."Rapid Communications In Mass Spectrometry. 2016 Au 7. [IF=1.902] Zhi Rao et al."Multicomponent determination of traditional Chinese medicine preparation yin-zhi-huang injection by LC–MS/MS for screening of its potential bioactive candidates using HepaRG cells."Biomed Chromatogr. 2018 Feb;32(2):e4057 8. [IF=4.411] Chunnan Li et al."Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells."Molecules. 2019 Jan;24(21):3920 9. [IF=3.935] Jie Li et al."Quality consistency evaluation between dispensing granules and traditional decoction of Gardeniae Fructus based on chemical similarity and bioequivalence."J Pharmaceut Biomed. 2022 May;213:114708 |
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