橘皮苷
二氢黄酮甙(Hesperiden)
CAS: 520-26-3
化学式: C28H34O15
性质
基本上不溶于水、乙醚、丙酮、氯仿和苯，1克橙皮苷可溶于50L水。比旋光度为- 76。（2%，吡啶中）。具有增强毛皮血管管壁的作用。
制法
主要以柠檬、柑橘、代代花等果实皮为原料制取。
用途
可用作营养强化剂。
| 中文名 | 二氢黄酮甙 |
| 英文名 | Hesperiden |
| 别名 | 柑果甙 橙皮苷 陈皮甙 桔皮甙 橙皮甙 橘皮苷 柚皮式 二氢黄酮苷 二氢黄酮甙 橙皮苷,橙皮甙 纳米脂质体橙皮苷 橙皮苷, 来源于枳实 橙皮苷(分析标准品) HESPERIDIN 橙皮苷 5-羟基-2-(3-羟基-4-甲氧苯基)-7-((3,4,5-三羟基-6-(((3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-2-基)氧基)色满-4-酮 二氢黄酮甙(地奥司明杂质) |
| 英文别名 | NSC44184 Cirantin Usaf cf-3 Vitamin P Hesperidin Hesperiden Hesperidine Hesperidoside Glucopyranoside (2S)-Hesperidin S)-(-)-Hesperidine Hesperetin 7-rutinoside Hesperetin-7-rutinoside Hesperitin-7-rhamnoglucoside Hesperetin 7-rhamnoglucoside hesperetin-7[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)]-beta-D- Hesperidin,Hesperetin 7-rhamnoglucoside, Hesperitin-7-rutinoside Hesperetin 7-[6-O- (6-deoxy-.alpha.-L-mannopyranosyl)]-.beta.-D-gluco pyranosid e) 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside 7-[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyloxy]-2α-(3-hydroxy-4-methoxyphenyl)-5-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-beta-L-mannopyranosyl)-beta-D-glucopyranoside (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside (S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[3,4,5-trihydroxy-6-[(3,4,5 -trihydroxy-6-methyl-oxan-2-yl)oxymethyl]oxan-2-yl]oxy-chroman-4-one (s)-7-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4h-1-benzopyran-4-one (S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-erythro-hexopyranosyl)-beta-D-threo-hexopyranoside 7-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.be ta.-D-glucopyranosyl ]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methox yphenyl)-, (S)-, 4H-1-Benzopyran-4-one, 7-[[6-O- (6-deoxy-.alpha.-L-mannopyranosyl-.bet a.-D-glucopyranosyl] oxy]-2,3-dihydro-5-hydr |
| CAS | 520-26-3 |
| EINECS | 208-288-1 |
| 化学式 | C28H34O15 |
| 分子量 | 610.56 |
| InChI | InChI=1/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10?,17-,19?,21-,22+,23-,24-,25?,26?,27+,28+/m0/s1 |
| InChIKey | QUQPHWDTPGMPEX-QJBIFVCTSA-N |
| 密度 | 1.3290 (rough estimate) |
| 熔点 | 250-255°C (dec.)(lit.) |
| 沸点 | 576.16°C (rough estimate) |
| 比旋光度 | -76 º (c=2,pyridine) |
| 闪点 | 305.5°C |
| 水溶性 | Insoluble in water. Soluble in organic solvents such as DMSO. |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | DMSO (微溶)，吡啶 (微溶，超声处理) |
| 折射率 | 1.5940 (estimate) |
| 酸度系数 | 7.15±0.40(Predicted) |
| 存储条件 | Sealed in dry,2-8°C |
| 稳定性 | 稳定。与强氧化剂不相容。 |
| 敏感性 | Hygroscopic |
| 外观 | 粉末 |
| 颜色 | light brown |
| Merck | 14,4671 |
| BRN | 75140 |
| 物化性质 | 来源于陈皮 |
| MDL号 | MFCD00075663 |
| 危险品标志 | Xi - 刺激性物品 |
| 风险术语 | R22 - 吞食有害。 R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
| 安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S27 - 一旦衣物受到污染，请立即脱去。 S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 |
| WGK Germany | 3 |
| RTECS | MK6650000 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| 海关编号 | 29389090 |
| 上游原料 | 皮粉 柚皮甙 |
| 下游产品 | 亚油酸乙酯 |
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[IF=4.35] Qian Yu et al."Aged Pericarpium Citri Reticulatae ‘Chachi’ Attenuates Oxidative Damage Induced by tert-Butyl Hydroperoxide (t-BHP) in HepG2 Cells."Foods. 2022 Jan;11(3):273 77. [IF=2.72] Jiang Sun et al."Adding sorbitol improves the thermostability of α-l-rhamnosidase from Aspergillus niger and increases the conversion of hesperidin."Journal Of Food Biochemistry. 2021 Dec 30 78. [IF=4.412] Hui-Min Jin et al."Polyphenol and Anthocyanin Composition and Activity of Highland Barley with Different Colors."MOLECULES. 2022 Jan;27(11):3411 79. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 80. [IF=6.53] Pan Sun et al."Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis."BIOMEDICINE & PHARMACOTHERAPY. 2022 Jun;150:112975 81. 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橘皮苷 - 性质
可信数据
基本上不溶于水、乙醚、丙酮、氯仿和苯，1克橙皮苷可溶于50L水。比旋光度为- 76。（2%，吡啶中）。具有增强毛皮血管管壁的作用。
最后更新：2024-01-02 23:10:35
橘皮苷 - 制法
可信数据
主要以柠檬、柑橘、代代花等果实皮为原料制取。
最后更新：2022-01-01 11:13:51
橘皮苷 - 用途
可信数据
可用作营养强化剂。
最后更新：2022-01-01 11:13:51
橘皮苷 - 简介
二氢黄酮甙是一种天然的植物化合物，可以在多种植物中找到。它的化学结构包括一个二氢黄酮环和一个糖基团。二氢黄酮甙具有多种生物活性，包括抗氧化、抗炎、抗菌、抗病毒等。
它具有抗氧化作用，可以保护细胞免受自由基的损害，进而预防心脑血管疾病和癌症等疾病的发生。二氢黄酮甙还具有抗炎作用，可用于缓解炎症疾病和风湿性关节炎等。还有研究表明，二氢黄酮甙对肝脏保护、降血糖、抗肿瘤等方面具有一定的功效。
制备二氢黄酮甙的方法较为多样，一般可以从植物中提取，或通过合成化学方法得到。提取法主要是将含有二氢黄酮甙的植物材料进行浸提，然后通过溶剂萃取、蒸馏等技术得到纯化的二氢黄酮甙。化学合成方法则是通过有机合成反应来构建二氢黄酮环，并在适当条件下与糖基团结合。
二氢黄酮甙的安全性，一般来说它被认为是相对安全的。对于某些特定的人群，如孕妇、哺乳期妇女、儿童等，应慎重使用或遵医嘱。使用二氢黄酮甙的产品时，应注意其用量和使用方法，避免过量使用导致不适反应。对于个体过敏的人群，应避免使用含有二氢黄酮甙的产品，以免引发过敏反应。
它具有抗氧化作用，可以保护细胞免受自由基的损害，进而预防心脑血管疾病和癌症等疾病的发生。二氢黄酮甙还具有抗炎作用，可用于缓解炎症疾病和风湿性关节炎等。还有研究表明，二氢黄酮甙对肝脏保护、降血糖、抗肿瘤等方面具有一定的功效。
制备二氢黄酮甙的方法较为多样，一般可以从植物中提取，或通过合成化学方法得到。提取法主要是将含有二氢黄酮甙的植物材料进行浸提，然后通过溶剂萃取、蒸馏等技术得到纯化的二氢黄酮甙。化学合成方法则是通过有机合成反应来构建二氢黄酮环，并在适当条件下与糖基团结合。
二氢黄酮甙的安全性，一般来说它被认为是相对安全的。对于某些特定的人群，如孕妇、哺乳期妇女、儿童等，应慎重使用或遵医嘱。使用二氢黄酮甙的产品时，应注意其用量和使用方法，避免过量使用导致不适反应。对于个体过敏的人群，应避免使用含有二氢黄酮甙的产品，以免引发过敏反应。
最后更新：2024-04-09 21:54:55
供应商列表
提供多种规格现货供应
产品名: 橙皮苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IH00401
产地: 北京
包装: 1ml/瓶
规格: IH00401-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
提供多种规格现货供应
产品名: 橙皮苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IH00401
产地: 北京
包装: 1ml/瓶
规格: IH00401-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
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