洛匹那韦代谢物M1

中文名	洛匹那韦代谢物M1
英文名	Lopinavir Metabolite M-1
别名	洛匹那韦代谢物M1
英文别名	4-Oxo-ABT-378 Lopinavir Impurity 22 Lopinavir IP Impurity E Lopinavir Metabolite M-1 (aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami-d (αS)-N-[(1S,3S,4S)-4-[[(2,6-DiMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2,4-dioxo-1(2H)-pyriMidineacetaMi-de (aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami-de (aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami- de
CAS	192725-39-6
化学式	C37H46N4O6
分子量	642.792
熔点	106-108°C
溶解度	氯仿 (微溶) 、甲醇 (微溶)
存储条件	-20°C Freezer
外观	固体
颜色	Off-White
体外研究	Lopinavir Metabolite M-1 has antiviral activities in MT-4 cells, with an EC 50 of 1.413 μM.