中文名 | 盐酸奥替尼啶 |
英文名 | N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride |
别名 | 奥替尼啶杂质 盐酸奥替尼啶 奥替尼啶盐酸盐 奥克太啶盐酸盐 奥替尼定盐酸盐 奥替尼啶,奥克太啶 奥替尼啶 二盐酸盐 奥替尼啶 奥克太啶(双盐酸盐) |
英文别名 | Octenidine HCl Octenidine hydrochloride ocenidine dihydrochloride OCTENIDINE DIHYDROCHLORIDE N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylaMMoniuM) dichloride N,N'-(decane-1,10-diyldipyridin-1-yl-4-ylidene)dioctan-1-amine dihydrochloride N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride |
CAS | 70775-75-6 |
EINECS | 274-861-8 |
化学式 | C36H64Cl2N4 |
分子量 | 623.82616 |
InChI | InChI=1/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1H |
InChIKey | SMGTYJPMKXNQFY-UHFFFAOYSA-N |
密度 | 1.046[at 20℃] |
熔点 | 215-217℃ |
沸点 | 609.3°C at 760 mmHg |
闪点 | 322.3°C |
水溶性 | 14.2g/L at 20℃ |
蒸汽压 | 0Pa at 25℃ |
溶解度 | 溶于二甲亚砜和甲醇。 |
存储条件 | Keep in dark place,Inert atmosphere,Room temperature |
稳定性 | 吸湿性 |
外观 | 固体 |
颜色 | White to Off-White |
Merck | 14,6754 |
体外研究 | Octenidine concentrations of less than1.5 μM (0.94 μg/mL) causes a greater than 99% reduction of tested microbial population within 15 min. Staphylococcus epidermidis is the most susceptible of the test organisms, and E. coli and C. albicans are the least susceptible. |
体内研究 | The antimicrobial activity of octenidine hydrochloride (OCT) is maintained when applied to the skin of the hands and feet of cynomolgus monkeys. Aqueous octenidine, at a concentration of 0.2 to 1.6% reduces resident microflora populations from 90 to 99.98%. A significant reduction in plaque score is observed on the buccal tooth surfaces after daily topical application of 1% solutions of octenidine and chlorhexidine for 7 d; octenidine is more effective than chlorhexidine. |
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