中文名 | 盐酸美利蒽 |
英文名 | melitracen hydrochloride |
别名 | 盐酸美利蒽 盐酸美力他欣 盐酸美利曲辛 美利曲辛盐酸盐 盐酸MELITRACEN 盐酸美利曲辛 MELITRACEN 成品工作对照品 3-[10,10-二甲基-9(10H)-蒽亚基]-N,N-二甲基丙胺盐酸盐 3-[10,10-二甲基-9(10H)- 亚蒽基]-N,N-二甲基丙胺盐酸盐 |
英文别名 | MELITRACEN HYDROCHLORLD MELITRACEN HYDROCHLORID melitracen hydrochloride Melitracen Hydrochlorlde Melitracen hydrochloride 3-(10,10-dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine 3-[10,10-dimethyl-9(10H)-anthrylidene]-N,N-dimethylpropylamine hydrochloride 3-[10,10-Dimethyl-9(10H)-anthrylidene]-N,N-dimethylpropylamine hydrochloride 9-(3-Dimethylaminopropylidene)-10,10-dimethyl-9,10-dihydroanthracene Hydrochloride 3-(10,10-Dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine Hydrochloride 1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-, hydrochloride |
CAS | 10563-70-9 |
EINECS | 234-150-5 |
化学式 | C21H26ClN |
分子量 | 327.89084 |
InChI | InChI=1/C21H25N/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21/h5-8,10-14H,9,15H2,1-4H3 |
密度 | 1.046g/cm3 |
熔点 | 245-248°C |
沸点 | 399.1°C at 760 mmHg |
闪点 | 174.4°C |
蒸汽压 | 1.4E-06mmHg at 25°C |
折射率 | 1.607 |
存储条件 | Sealed in dry,Room Temperature |
外观 | 结晶固体 |
体内研究 | Single oral administration of either Imipramine or Melitracen produces a marked and long lasting mydriasis in mice. The mydriatic effect of Melitracen is more marked and longer lasting. Melitracen is more effective with respect to behavioral excitement. Single oral administration of Melitracen produces lowering of the catechol amine levels in the brain stem, the cerebral cortex, the spleen, and the adrenals. No significant changes in catecholamine levels of the brain stem, the cerebral cortex, and the spleen were observed in rats receiving daily doses of Melitracen for 13 and 15 weeks. The adrenalin level in the adrenals, however, is slightly decreased. |
上游原料 | 镁 盐酸 3-氯-1-(N,N-二甲基)丙胺 |
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