中文名 | 芹甙元-7-葡萄糖苷 |
英文名 | 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
别名 | 芹黄素-7-葡糖苷 芹甙元-7-葡萄糖苷 芹菜素7-O-葡糖苷 芹菜素-7-0-葡萄糖苷 芹菜素-7-O-Β-D-葡萄吡喃糖苷 大波斯菊苷,芹菜素-7-O-Β-D-吡喃葡萄糖苷(标准品) 大波斯菊苷,芹菜素-7-葡萄糖苷,芹菜素-7-O-Β-D-葡萄糖苷 APIGENIN-7-O-Β-D-GLUCOPYRANOSIDE 芹菜素-7-O-Β-D-吡喃葡萄糖苷 芹菜素-7-O-Β-D-吡喃葡萄糖苷(大波斯菊苷,芹菜素-7-葡萄糖苷,芹菜素-7-O-Β-D-葡萄糖苷) |
英文别名 | COSMETIN Apigetrin Cosemetin Cosmosiin Cosmosiine NSC 407303 Cosmosioside Cosmosiin (8CI) Apgenin-7-Gglucoside Apigenin 7-b-D-glucoside Apigenin 7-beta-D-glucoside Apigenin 7-O-beta-D-glucoside 7-O-(beta-D-Glucosyl)apigenin Apigetrin(Apigenin-7-O-glucoside) Apigenin, 7-beta-D-glucopyranoside Apigenin 7-O-beta-D-glucopyranoside 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl hexopyranoside 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-galactopyranoside 4H-1-Benzopyran-4-one,7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl) 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- 7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- (9CI) |
CAS | 578-74-5 |
EINECS | 209-430-5 |
化学式 | C21H20O10 |
分子量 | 432.38 |
InChI | InChI=1/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2/t16-,18+,19+,20-,21-/m1/s1 |
密度 | 1.642±0.06 g/cm3(Predicted) |
熔点 | 230-237°C |
沸点 | 788.9±60.0 °C(Predicted) |
比旋光度 | (Py)-64 |
闪点 | 280.7°C |
蒸汽压 | 3.14E-26mmHg at 25°C |
溶解度 | DMSO (微溶,超声处理),甲醇 (微溶) |
折射率 | 1.717 |
酸度系数 | 6.13±0.40(Predicted) |
存储条件 | Inert atmosphere,2-8°C |
外观 | 整洁 |
颜色 | Pale Yellow to Yellow |
BRN | 65669 |
物化性质 | 白色结晶体,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于广藿香、仙鹤草,蓰草,构树叶。 |
MDL号 | MFCD00016787 |
体外研究 | Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells. Apigenin 7-glucoside specifically induces the differentiation of CD34 + cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10 |
海关编号 | 29389090 |
参考资料 展开查看 | 1. 韩星, 李雪岩, 杨海洋,等. 菊花水提物的质量控制成分筛选及其网络药理学作用研究[J]. 中国药房, 2019, 030(023):3258-3265. 2. 谭湘杰 于福来 黄梅 等. 不同初加工方式对裸花紫珠主要化学成分含量影响[J]. 热带农业科学 2018 v.38;No.251(07):36-42. 3. Qiang Zhang, Ruiyun Huo, Yibo Ma, Shuangmei Yan, Lei Yang, Fengli Chen,A novel microwave-assisted steam distillation approach for separation of essential oil from tree peony (Paeonia suffruticosa Andrews) petals: Optimization, kinetic, chemical compositio 4. Liu, Chanmin, et al. "Flavonoid-rich extract of Paulownia fortunei flowers attenuates diet-induced hyperlipidemia, hepatic steatosis and insulin resistance in obesity mice by AMPK pathway." Nutrients 9.9 (2017): 959.https://doi.org/10.3390/nu9090959 5. [IF=7.514] Chu-Yang Wang et al."Isolation of wheat mutants with higher grain phenolics to enhance anti-oxidant potential."Food Chem. 2020 Jan;303:125363 6. [IF=5.645] Zhang-Zhen Bai et al."Comparative investigation on metabolites and biological activities of Paeonia ostii stamens from different geographical regions of China."Ind Crop Prod. 2021 Nov;172:114038 7. [IF=5.645] Qiang Zhang et al."A novel microwave-assisted steam distillation approach for separation of essential oil from tree peony (Paeonia suffruticosa Andrews) petals: Optimization, kinetic, chemical composition and antioxidant activity."Ind Crop Prod. 2020 Oct; 8. [IF=4.821] Xiangwei Chang et al."Untargeted metabolomics approach reveals the tissue-specific markers of balloon flower root (Platycodi Radix) using UPLC-Q-TOF/MS."Microchem J. 2021 Sep;168:106447 9. [IF=4.759] Fengli Chen et al."Magnetically stabilized bed packed with synthesized magnetic silicone loaded with ionic liquid particles for efficient enrichment of flavonoids from tree peony petals."J Chromatogr A. 2020 Feb;1613:460671 10. [IF=4.411] Yi Li et al."Evaluation of Anti-Inflammatory and Antioxidant Effectsof Chrysanthemum Stem and Leaf Extract on Zebrafish Inflammatory Bowel Disease Model."Molecules. 2022 Jan;27(7):2114 11. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 12. [IF=2.863] Jue Cui et al."Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells."Food Science & Nutrition |
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