金丝桃苷
金丝桃苷(Hyperin)
CAS: 482-36-0
化学式: C21H20O12
| 中文名 | 金丝桃苷 |
| 英文名 | Hyperin |
| 别名 | 海棠因 金丝桃甙 金丝桃苷 田基黄甙 海棠黃酮 槲皮素-3-半乳糖甙 槲皮素-3-D-半乳糖苷 2-(3,4-二羟基苯基)-3-(beta-D-吡喃半乳糖氧基)-5,7-二羟基-4H-1-苯并吡喃-4-酮 |
| 英文别名 | Hyperin HYPERIN HYPEROSID Hyperosid Hyperasid hyperasid Hyperozide HYPEROSIDE hyperozide Hyperoside NSC 407304 Hyperin (8CI) Quercetin-3-galactoside QUERCETIN-3-D-GALACTOSIDE Quercetin-3-O-galactoside QUERCETIN-3-O-GALACTOSIDE QUERCETIN-3B-D-GALACTOSIDE Quercetin 3-beta-D-galactopyranoside Quercetin 3-O-beta-D-galactopyranoside 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl hexopyranoside 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl D-glucopyranoside 2-(3,4-Dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy- |
| CAS | 482-36-0 |
| EINECS | 207-580-6 |
| 化学式 | C21H20O12 |
| 分子量 | 464.38 |
| InChI | InChI=1/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21?/m1/s1 |
| 密度 | 1.87±0.1 g/cm3(Predicted) |
| 熔点 | 225-226°C |
| 沸点 | 872.6±65.0 °C(Predicted) |
| 比旋光度 | -83°（c=0.2，pyridine） |
| 闪点 | 307.473°C |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | DMSO (微溶)，甲醇 (微溶，加热) |
| 折射率 | 1.803 |
| 酸度系数 | 6.17±0.40(Predicted) |
| 存储条件 | -20°C |
| 外观 | 固体 |
| 颜色 | Light Yellow to Yellow |
| BRN | 5784795 |
| 物化性质 | 易溶于乙醇、甲醇、丙酮和吡啶。 来源于金丝桃科的果实与全草中。 |
| MDL号 | MFCD00016933 |
| 危险品标志 | Xn - 有害物品 |
| 风险术语 | R22 - 吞食有害。 R40 - 少数报道有致癌后果。 |
| 安全术语 | S22 - 切勿吸入粉尘。 S45 - 若发生事故或感不适，立即就医(可能的话，出示其标签)。 S36 - 穿戴适当的防护服。 S24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| RTECS | DJ3009200 |
| FLUKA BRAND F CODES | 10-23 |
| 海关编号 | 29389090 |
| 参考资料 展开查看 | 1. 王洪成 尹海波 曹波 等. HPLC同时测定不同产地野老鹳草中5种活性成分含量[J]. 辽宁中医杂志 2015(04):834-836. 2. 吴仲 张勋.HPLC法同时测定山楂异槲皮苷和金丝桃苷含量[J].吉林中医药 2019 39(07):949-952. 3. 邓泽丽[1] Oh Young Joo[2] 李洪军[1] Tae Seok Kim[2] 项怡[1] Ik Hyun Yeo[2] 贺稚非[1]. 响应面分析法优化超声辅助提取山楂中总黄酮的工艺[J]. 西南大学学报(自然科学版) 2014(36):160-166. 4. 李小蓉, 郭惠, 龙旭,等. 基于碳纳米管组装电化学传感器测定金丝桃苷的含量[J]. 食品工业科技, 2019(15):220-224. 5. 赵博,田恒康,孙道涵,申立峰,孔静,路东波,李文霞,武秋红,刘璐,李倩,张元元,吕珊,陈梦杰,石任兵.基于酚类特征图谱的山楂质量表征关联分析研究[J].北京中医药大学学报,2017,40(08):684-692. 6. 杨梅, 余建强, 郑萍,等. 复方枸杞泡腾片的制备及含量测定[J]. 食品研究与开发, 2019, 040(022):138-144. 7. 邓泽丽, 李洪军, 甘奕,等. 山楂饮料发酵工艺[J]. 食品与发酵工业, 2015, 41(010):86-89. 8. 石晓晨, 王蕾, 王尧尧,等. 干燥方式对山楂总黄酮总有机酸含量的影响[J]. 山东科学, 2018, 031(005):14-19. 9. 张孟丽, 张卫明, 束成杰. 新疆罗布红麻花,种子及叶中金丝桃苷含量比较[J]. 湖北农业科学, 2019, 058(017):66-68,73. 10. 王艳, 张俊妹, 郭金凤,等. 榆叶合叶子黄酮类成分的微乳薄层色谱鉴别[J]. 新疆医科大学学报, 2015, 000(001):61-63. 11. 刘善新. 神交汤颗粒的水提工艺研究[J]. 辽宁中医杂志(10). 12. 仇燕, 刘畅, QIU,等. 菜芙蓉花活性部位体外氧化损伤的保护作用[J]. 精细化工, 2017, 07(v.34):70-75. 13. 谷静逸, 尹海波, 赵容,等. 辽宁省5种老鹳草中5种活性成分的含量测定[J]. 中国实验方剂学杂志, 2016, 022(006):26-29. 14. 李莹,周燏,孙蕾清,周忠海,吕小婷,徐明,李昳,刘军权.金丝桃苷增强人γδT细胞增殖及杀伤功能研究[J].中国免疫学杂志,2016,32(04):524-527. 15. 白鑫宇, 杨晓峰, 赵叶利,等. 金丝桃苷对内毒素(LPS)诱导的小鼠急性肾损伤的保护作用[J]. 沈阳药科大学学报, 2014, 031(010):799-803. 16. 申冬冬, 侯江红, 袁飞. 金丝桃苷抑制肺炎支原体肺炎模型小鼠的损伤[J]. 中国病理生理杂志, 2017(5). 17. 郑梅竹, 范亚军, 潘炎,等. 金丝桃苷抗抑郁作用参与5-HT能系统可能机制研究[J]. 长春师范大学学报, 2018, v.37;No.345(08):88-92. 18. 周燏, 高小宁, 吕小婷,等. 金丝桃苷增强人NK细胞增殖及功能的研究[J]. 中国免疫学杂志, 2019, 35(013):1569-1572. 19. 曹波 尹海波 贾晓晴 等. HPLC法同时测定3种老鹳草中7种成分[J]. 中成药 2016 38(6):1338-1342. 20. 王艳 张芳 姚军 等. HPLC法测定榆叶合叶子中绣线菊苷 金丝桃苷 芦丁 槲皮素[J]. 中成药 2013 35(8):1714-1714. 21. 王芳,计巧灵,邓倩,李玉薇.培养条件对罗布麻愈伤组织中金丝桃苷和异槲皮苷积累的影响[J].中成药,2012,34(10):1966-1971. 22. 范铭, 向露, 徐文慧,等. 大孔树脂纯化桑葚渣中α-淀粉酶抑制剂的工艺优化及其活性成分研究[J]. 浙江农业学报, 2019, 031(007):1154-1160. 23. 杨晓博, 王荣芳, 贾亚楠,等. 高效液相色谱法测定山楂叶中的9种酚类成分[J]. 食品工业科技, 2017, 38(010):62-66. 24. 沈经纬 刘畅 白一丹 等. 五凤草液的HPLC指纹图谱建立与有效部位的质量控制[J]. 海峡药学 2020 032(004):39-44. 25. 金银萍 曲正义 崔丽丽 等. 五味子不同部位黄酮和酚酸类成分的含量测定及抗氧化活性[J]. 中国实验方剂学杂志 2018(19). 26. 马云, 王尧尧, 王蕾,等. 忍冬花发育期间形态与13种活性成分含量变化[J]. 中药材, 2018, 041(007):1559-1565. 27. 梁琰, 张贵民, 苏瑞强,等. 小儿消积止咳口服液多指标成分分析及其HPLC指纹图谱研究[J]. 中草药, 2017(21):79-86. 28. 王聪 付士朋 金司阳 等. 不同产地刺五加果实中5种活性成分的含量测定及聚类分析[J]. 时珍国医国药 2019 v.30;No.288(08):196-198. 29. 高芯, 万瑶瑶, 李长印,等. 基于液相色谱-飞行时间质谱联用和质量亏损过滤技术的黄葵黄酮类成分系统分析[J]. 分析化学, 2020. 30. 陈希苗, 李美英, 许秋莉,等. 体外模拟胃肠消化中山楂多酚及抗氧化活性的变化[J]. 食品科学, 2019, 040(005):31-37. 31. 朱姮, 于金倩, 刘倩,等. 基于RRLC-DAD-ESI-Q-TOF-MS技术的山东金银花多指标定量指纹图谱分析[J]. 中国实验方剂学杂志, 2017, 023(019):82-89. 32. 朱伟 赵赫 姚岚 等. UFLC-MS/MS法同时测定肺宁颗粒中6种化学成分[J]. 解放军药学学报 2017(04):356-358. 33. 石晓晨 刘红艳 刘谦 等. 一测多评法测定山楂中7种成分含量[J]. 中药材 2019(1):116-121. 34. 谭立,孔静,冯朵,刘璐,吕珊,张元元,石任兵.基于抗心肌缺血作用的金花葵制备物药物质量表征分析[J].世界科学技术-中医药现代化,2017,19(03):522-528. 35. 金银萍, 王英平, 王振兴,等. 超高效液相色谱法测定不同种质资源五味子藤茎中5种黄酮类成分的含量[J]. 天然产物研究与开发, 2018, 030(001):61-64. 36. 夏昆瑜, 张春磊, 曹征宇,等. 黄蜀葵花的化学成分研究[J]. 海峡药学, 2019, v.31;No.236(09):62-65. 37. 王玲娜,张芳,李佳,刘红燕,姜秋,张永清.金银花新品种“华金6号”药材品质比较研究[J].中药材,2019,42(09):2030-2035. 38. 崔欣悦 凌空 周明 等. 乳酸菌发酵柑橘皮的工艺研究及优化[J]. 食品研究与开发 2019 40(08):135-142. 39. 赵志国, 井凤, 张敏敏,等. 西藏木瓜HPLC指纹图谱研究及多成分测定[J]. 中草药, 2018, 49(10):239-244. 40. 李俊萍, 付士朋, 王谦博,等. 多指标综合评价刺五加叶适宜采收期的研究[J]. 中草药, 2019, v.50;No.648(13):196-201. 41. 金司阳, 刘寒, 杨立学,等. 植物-土壤反馈对刺五加幼苗次生代谢产物的影响[J]. 中国实验方剂学杂志, 2020. 42. 张威鹏,朱雯,张良,付冬梅,张子东,张琳,祖元刚.HPLC法同时测定不同采收年限及部位杜仲中5种黄酮类成分[J].黑龙江医药,2020,33(06):1267-1270. 43. 汪颖舒,朱广灏,王冰,李杰荣,骆前飞,何修滢,赵佳逸,修彦凤.古法黑豆蒸晒与药典黑豆汁连续蒸对何首乌中12个成分含量的影响[J].中草药,2020,51(19):4972-4982. 44. 倪昌荣,袁淑婧.LC-MS法测定菟丝子药材在大鼠血浆中活性成分金丝桃苷的药代动力学研究[J].中医药导报,2020,26(16):61-64. 45. 王西彬,左瑞庭.金丝桃苷对IL-1β诱导的小鼠骶髂关节软骨细胞损伤的影响[J].中成药,2021,43(02):369-373. 46. 范小龙,陈冉,吴婉琴,刘国姣,黄坤,江丰.液相色谱串联质谱法测定食品中淫羊藿苷等20种功能成分[J].食品与机械,2021,37(01):86-93+98. 47. 吴裕红,彭新宇,张嘉慧,陈文露,徐志宏,龙晓英.枫蓼提取物成分分析及其主要成分黄酮对肠平滑肌的药效学研究[J].黑龙江畜牧兽医,2021(02):128-136. 48. 王宇卿,李淑娇,庄果.基于HPLC-Q-TOF/MS法的鬼针草血清药物化学探究[J].中成药,2020,42(11):3074-3078. 49. 周建新,沈硕,杜茂波,李玉洁,孙奕,何爱萍,姚瑶,王明硕,刘淑芝,尹永芹.基于UPLC-Q-TOF-MS技术和整合药理学方法探索吴茱萸经皮成分及其治疗腹泻的分子机制[J].中国实验方剂学杂志,2021,27(07):112-120. 50. Zhang, Minmin, et al. "Chemical characterization and evaluation of the antioxidants in Chaenomeles fruits by an improved HPLC-TOF/MS coupled to an on-line DPPH-HPLC method." Journal of Environmental Science and Health, Part C 36.1 (2018): 43-62.https://doi 51. Lei, Tianli, et al. "Characterization and discrimination of raw and vinegar‐baked Bupleuri radix based on UHPLC‐Q‐TOF‐MS coupled with multivariate statistical analysis." Biomedical Chromatography 32.2 (2018): e4044.https://doi.org/10.1002/bmc.4044 52. Liu, Tongji, et al. "Improvement effect of lotus leaf flavonoids on carbon tetrachloride-induced liver injury in mice." Biomedicines 8.2 (2020): 41.https://doi.org/10.3390/biomedicines8020041 53. Tiantian Tang, Xinfang Xie, Xue Ren, Wenjun Wang, Xuanming Tang, Jie Zhang, Zhidong Wang, A difference of enzymatic browning unrelated to PPO from physiology, targeted metabolomics and gene expression analysis in Fuji apples, Postharvest Biology and Techno 54. Cao, Yanni, et al. "Chemical fingerprint and multicomponent quantitative analysis for the quality evaluation of Cyclocarya paliurus leaves by HPLC–Q–TOF–MS." Molecules 22.11 (2017): 1927.https://doi.org/10.3390/molecules22111927 55. Dong, Qingying, et al. "Comparative study on phenolic compounds, triterpenoids, and antioxidant activity of Ganoderma lucidum affected by different drying methods." Journal of Food Measurement and Characterization 13.4 (2019): 3198-3205.https://doi.org/10. 56. Dong, Qingying, et al. "Comparative study on phenolic compounds, triterpenoids, and antioxidant activity of Ganoderma lucidum affected by different drying methods." Journal of Food Measurement and Characterization 13.4 (2019): 3198-3205.https://doi.org/10. 57. Xue, Gen, et al. "Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA." Journal of Analytical Methods in Chemistry 2021 (2021).https://doi.org/10.11 58. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606 59. [IF=5.923] Cuihua Chen et al."Variations in Physiology and Multiple Bioactive Constituents under Salt Stress Provide Insight into the Quality Evaluation of Apocyni Veneti Folium."Int J Mol Sci. 2018 Oct;19(10):3042 60. [IF=5.279] Yingying Wei et al."Hot Air Treatment Induces Disease Resistance through Activating the Phenylpropanoid Metabolism in Cherry Tomato Fruit."J Agr Food Chem. 2017;65(36):8003–8010 61. [IF=4.759] Lu Wang et al."A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectr 62. [IF=4.411] Xiaosheng Tang et al."Molecular Structure–Affinity Relationship of Flavonoids in Lotus Leaf (Nelumbo nucifera Gaertn.) on Binding to Human Serum Albumin and Bovine Serum Albumin by Spectroscopic Method."Molecules. 2017 Jul;22(7):1036 63. [IF=4.411] Yanni Cao et al."Chemical Fingerprint and Multicomponent Quantitative Analysis for the Quality Evaluation of Cyclocarya paliurus Leaves by HPLC–Q–TOF–MS."Molecules. 2017 Nov;22(11):1927 64. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254 65. [IF=3.046] Liwei Dong et al."Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1."Oncotargets Ther. 2015; 8: 3649–3664 66. [IF=2.19] Yawei Zhang et al."Effects of high temperature steam treatment on microbial and phytochemical contents, antioxidant activities, chemical stability, and shelf life of oral liquid prepared from the leaves of Zanthoxylum bungeanum Maxim."J Food Process Pres. 67. [IF=1.981] Yan Qiu et al."Total Flavonoid Extract from Abelmoschus manihot (L.) Medic Flowers Attenuates d-Galactose-Induced Oxidative Stress in Mouse Liver Through the Nrf2 Pathway."J Med Food. 2017 Jun;20(6):557-567 68. [IF=1.902] Tianli Lei et al."Characterization and discrimination of raw and vinegar-baked Bupleuri radix based on UHPLC-Q-TOF-MS coupled with multivariate statistical analysis."Biomed Chromatogr. 2018 Feb;32(2):e4044 69. [IF=6.081] Tongji Liu et al."Improvement Effect of Lotus Leaf Flavonoids on Carbon Tetrachloride-Induced Liver Injury in Mice."Biomedicines. 2020 Feb;8(2):41 70. [IF=5.893] Yinglu Ren et al."Si-Miao-Yong-An decoction ameliorates cardiac function through restoring the equilibrium of SOD and NOX2 in heart failure mice."Pharmacol Res. 2019 Aug;146:104318 71. [IF=5.81] Jizhen Huang et al."Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.."Front Pharmacol. 2020 Oct 22;11:550955 72. [IF=5.537] Tiantian Tang et al."A difference of enzymatic browning unrelated to PPO from physiology, targeted metabolomics and gene expression analysis in Fuji apples."Postharvest Biol Tec. 2020 Dec;170:111323 73. [IF=5.455] Zhang Xian et al."Neurobehavioral alternations of the female offspring born to polycystic ovary syndrome model rats administered by Chinese herbal medicine."Chin Med-Uk. 2021 Dec;16(1):1-19 74. [IF=5.165] Huan Zhang et al."Fermentation characteristics and the dynamic trend of chemical components during fermentation of Massa Medicata Fermentata."Arab J Chem. 2022 Jan;15:103472 75. [IF=5.103] Mingjun Su et al."Coronavirus Porcine Epidemic Diarrhea Virus Nucleocapsid Protein Interacts with p53 To Induce Cell Cycle Arrest in S-Phase and Promotes Viral Replication | Journal of Virology."J Virol. 2021 Jul;: 76. [IF=4.952] Ting Zhao et al."The antioxidant property and α-amylase inhibition activity of young apple polyphenols are related with apple varieties."Lwt Food Sci Technol. 2019 Aug;111:252 77. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625 78. [IF=4.379] Zhang Liang-Liang et al."Chemical composition, antibacterial activity and action mechanism of different extracts from hawthorn (Crataegus pinnatifida Bge.)."Sci Rep-Uk. 2020 Jun;10(1):1-13 79. [IF=4.379] Chen Cuihua et al."A strategy for quality evaluation of salt-treated Apocyni Veneti Folium and discovery of efficacy-associated markers by fingerprint-activity relationship modeling."Sci Rep-Uk. 2019 Nov;9(1):1-13 80. [IF=4.36] Yu Zhang et al."Screening of hypolipidemic active components in Jiang-Zhi-Ning and its preliminary mechanism research based on “active contribution value” study."J Ethnopharmacol. 2021 May;272:113926 81. [IF=4.35] Chengcheng Zhang et al."Chemical Characterization and Antioxidant Properties of Ethanolic Extract and Its Fractions from Sweet Potato (Ipomoea batatas L.) Leaves."Foods. 2020 Jan;9(1):15 82. [IF=4.27] Cuihua Chen et al."Metabolomics characterizes metabolic changes of Apocyni Veneti Folium in response to salt stress."Plant Physiol Bioch. 2019 Nov;144:187 83. [IF=4.235] Dong Qingying et al."High Oxygen Treatments Enhance the Contents of Phenolic Compound and Ganoderic Acid, and the Antioxidant and DNA Damage Protective Activities of Ganoderma lingzhi Fruiting Body."Front Microbiol. 2019 Oct;0:2363 84. [IF=4.225] Gu Li-fei et al."Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways."Front Pharmacol. 2020 Jul;0:996 85. [IF=4.162] Rong Wang et al."Total Flavone of Abelmoschus manihot Ameliorates Stress-Induced Microbial Alterations Drive Intestinal Barrier Injury in DSS Colitis."Drug Des Dev Ther. 2021; 15: 2999–3016 86. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697 87. [IF=3.978] Yunbin Lyu et al."Identification and characterization of three flavonoid 3-O-glycosyltransferases from Epimedium koreanum Nakai."Biochem Eng J. 2020 Nov;163:107759 88. [IF=3.765] Shun Liu et al."Simultaneous determination of seven effective components in Shenkui Tongmai granules based on UHPLC-MS/MS."J Pharm Pharmacol. 2021 Apr;73(6):758-766 89. [IF=3.69] Jianwen Cao et al."Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy."J Ethnopharmacol. 2020 Jul;257:112884 90. [IF=3.645] Lu Huang et al."Qualitative and quantitative analysis of chemical components in Eupatorium lindleyanum DC. by ultra-performance liquid chromatography-mass spectrometry integrated with anti-inflammatory activity research."J Sep Sci. 2021 Sep;44(17):3174-31 91. [IF=3.645] Jie Lu et al."Identification and determination of chemical constituents from Yinchen Qingjin granules by ultra high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry."J Sep Sci. 2021 Apr;44(7):1324-1344 92. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556 93. [IF=3.167] Li Yu et al."Quality evaluation of different varieties of Zanthoxylum bungeanum Maxim. peels based on phenolic profiles, bioactivity, and HPLC fingerprint."J Food Sci. 2020 Apr;85(4):1090-1097 94. [IF=2.72] Meiling Han et al."Phenolic compounds present in fruit extracts of Malus spp. show antioxidative and pro-apoptotic effects on human gastric cancer cell lines."J Food Biochem. 2019 Nov;43(11):e13028 95. [IF=2.633] Yanni Cao et al."Seasonal Variation in Phenolic Compounds and Antioxidant Activity in Leaves of Cyclocarya paliurus (Batal.) Iljinskaja."Forests. 2019 Aug;10(8):624 96. [IF=2.629] Wang Ting et al."Network Pharmacology Prediction and Pharmacological Verification Mechanism of Yeju Jiangya Decoction on Hypertension."Evid-Based Compl Alt. 2021;2021:5579129 97. [IF=2.464] Xiulan Xin et al."Study on the interaction of hyperoside and human serum albumin in VC and VC-free environments by spectroscopic and molecular docking techniques."Luminescence. 2021 May;36(3):595-605 98. [IF=2.431] Dong Qingying et al."Comparative study on phenolic compounds, triterpenoids, and antioxidant activity of Ganoderma lucidum affected by different drying methods."J Food Meas Charact. 2019 Dec;13(4):3198-3205 99. [IF=2.431] Su Shang et al."Diversity of red, green and black cultivars of Chinese Toon [Toona sinensis (A. Juss.) Roem]: anthocyanins, flavonols and antioxidant activity."J Food Meas Charact. 2020 Dec;14(6):3206-3215 100. [IF=2.193] Xue Gen et al."Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA."J Anal Methods Chem. 2021;2021:9991363 101. [IF=2.044] Yuan Wenjing et al."UPLC-MS/MS Method for the Determination of Hyperoside and Application to Pharmacokinetics Study in Rat After Different Administration Routes."Chromatographia. 2021 Mar;84(3):249-256 102. [IF=1.296] Han Meiling et al."Analysis of flavonoids and anthocyanin biosynthesis-related genes expression reveals the mechanism of petal color fading of Malus hupehensis (Rosaceae)."Braz J Bot. 2020 Mar;43(1):81-89 103. [IF=0.468] Yan Feng et al."Protective Effects and Mechanism of Hyperoside in PC12 Cells Against Oxidative Stress Injury Induced by Hydrogen Peroxide:."Nat Prod Commun. 2021;16(5): 104. [IF=3.645] Shuo Gu et al."Develop a stepwise integrated method to screen biomarkers of Baihe-Dihuang Tang on the treatment of depression in rats applying with composition screened, untargeted, and targeted metabolomics analysis."Journal Of Separation Science. 2022 M 105. [IF=1.312] Xiaoran Zhao et al."Discrimination of Cuscuta chinensis Lam. and Cuscuta japonica Choisy based on a combination of chemometrics and fingerprint classification."Journal Of Liquid Chromatography & Related Technologies. 2022 Jan 09 106. [IF=3.935] Junmao Li et al."Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering."J Pharmaceut Biomed. 2022 Mar;211:114621 107. [IF=4.932] Weifeng Zhu et al."Hyperoside Attenuates Zearalenone-induced spleen injury by suppressing oxidative stress and inhibiting apoptosis in mice."Int Immunopharmacol. 2022 Jan;102:108408 108. [IF=6.486] Ping Zheng et al."Comparative analyses of American and Asian lotus genomes reveal insights into petal color, carpel thermogenesis and domestication."PLANT JOURNAL. 2022 Apr 01 109. [IF=4.412] 110. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 111. [IF=5.165] Jia-huan Yuan et al."A study for quality evaluation of Taxilli Herba from different hosts based on fingerprint-activity relationship modeling and multivariate statistical analysis."Arabian Journal of Chemistry. 2022 Jul;15:103933 112. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 113. [IF=6.576] Yingchun Jin et al."Characteristics of Mulberry Leaf Powder Enriched With γ-Aminobutyric Acid and Its Antioxidant Capacity as a Potential Functional Food Ingredient."Frontiers in Nutrition. 2022; 9: 900718 114. [IF=4.24] Jun Li et al."In vitro xanthine oxidase inhibitory properties of Flos Sophorae Immaturus and potential mechanisms."Food Biosci. 2022 Jun;47:101711 |
金丝桃苷 - 简介
金丝桃苷是一种常见的天然化合物，化学名称为 digoxin。以下是金丝桃苷的性质、用途、制法和安全信息的介绍：
性质：
金丝桃苷是一种无色结晶固体，在水中微溶，易溶于乙醇、苯和醚。它是一种心苷类化合物，具有强烈的强心作用。金丝桃苷在体内经过代谢，形成活性成分地高辛。
用途：
金丝桃苷被广泛用于心脏病的治疗，特别是用于心力衰竭和心律失常的治疗。它可以通过增强心肌收缩力和改善心房传导，恢复心脏的正常功能。金丝桃苷也用于治疗心房颤动和心室颤动等病症。
制法：
金丝桃苷通过从金丝桃属植物中提取得到，可以通过泡蒸提取或从金丝桃的叶子、根茎中提取得到。提取后经过结晶、纯化和干燥等步骤，得到纯度较高的金丝桃苷。
安全信息：
金丝桃苷是一种强心制剂，具有一定的毒性和副作用。它不能随意使用，必须在医生的指导下使用。不当使用金丝桃苷可能会导致严重的心脏毒副作用，如心律失常、心动过速、心绞痛等。金丝桃苷还具有肾毒性和神经毒性，容易引起恶心、呕吐等不良反应。
性质：
金丝桃苷是一种无色结晶固体，在水中微溶，易溶于乙醇、苯和醚。它是一种心苷类化合物，具有强烈的强心作用。金丝桃苷在体内经过代谢，形成活性成分地高辛。
用途：
金丝桃苷被广泛用于心脏病的治疗，特别是用于心力衰竭和心律失常的治疗。它可以通过增强心肌收缩力和改善心房传导，恢复心脏的正常功能。金丝桃苷也用于治疗心房颤动和心室颤动等病症。
制法：
金丝桃苷通过从金丝桃属植物中提取得到，可以通过泡蒸提取或从金丝桃的叶子、根茎中提取得到。提取后经过结晶、纯化和干燥等步骤，得到纯度较高的金丝桃苷。
安全信息：
金丝桃苷是一种强心制剂，具有一定的毒性和副作用。它不能随意使用，必须在医生的指导下使用。不当使用金丝桃苷可能会导致严重的心脏毒副作用，如心律失常、心动过速、心绞痛等。金丝桃苷还具有肾毒性和神经毒性，容易引起恶心、呕吐等不良反应。
最后更新：2024-04-09 21:11:58
供应商列表
提供多种规格现货供应
产品名: 金丝桃苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IH03801
产地: 北京
包装: 1ml/瓶
规格: IH03801-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
提供多种规格现货供应
产品名: 金丝桃苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IH03801
产地: 北京
包装: 1ml/瓶
规格: IH03801-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
金丝桃苷的下游产品
您刚刚浏览过
你知道吗？
微信搜索化工百科或扫描下方二维码，添加化工百科小程序，随时随地查信息！