中文名 | 鸡矢藤次苷甲酯 |
英文名 | methyl (1S,4aS,5R,7aS)-1-(beta-D-glucopyranosyloxy)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate |
别名 | 山栀苷甲酯 鸡失藤次苷 鸡失藤次苷甲酯 鸡矢藤次苷甲酯 鸡屎藤次甙甲酯 6Β-羟基-京尼平苷 6-BETA-羟基栀子苷 6Β-羟基-京尼平苷标准品 6-BETA-羟基栀子苷,鸡矢藤次苷甲酯 |
英文别名 | Feretoside 6β-Hydroxygeniposide Scandoside methyl ester Scandioside methyl ester Deacetylasperuculosidic acid methyl ester (1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,5,7aα-tetrahydro-5α-hydroxy-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester (1S)-7-(Hydroxymethyl)-1α-(β-D-glucopyranosyloxy)-1,4aα,5,7aα-tetrahydro-5β-hydroxycyclopenta[c]pyran-4-carboxylic acid methyl ester methyl (1S,4aS,5R,7aS)-1-(beta-D-glucopyranosyloxy)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (1S)-1α-(β-D-Glucopyranosyloxy)-5α-hydroxy-7-(hydroxymethyl)-1,4aα,5,7aα-tetrahydrocyclopenta[c]pyran-4-carboxylic acid methyl ester |
CAS | 27530-67-2 |
化学式 | C17H24O11 |
分子量 | 404.37 |
InChI | InChI=1/C17H24O11/c1-25-15(24)7-5-26-16(10-6(3-18)2-8(20)11(7)10)28-17-14(23)13(22)12(21)9(4-19)27-17/h2,5,8-14,16-23H,3-4H2,1H3/t8-,9-,10-,11+,12-,13+,14-,16+,17+/m1/s1 |
密度 | 1.61±0.1 g/cm3(Predicted) |
熔点 | 90°C (dec.) |
沸点 | 696.3±55.0 °C(Predicted) |
比旋光度 | -110.8 (c, 0.42 in MeOH) |
闪点 | 250.9°C |
蒸汽压 | 2E-22mmHg at 25°C |
溶解度 | 易溶于水、甲醇和乙醇,难溶于乙酸乙酯,不溶于氯仿、苯和石油醚。 |
折射率 | 1.64 |
酸度系数 | 12.80±0.70(Predicted) |
存储条件 | 2-8℃ |
敏感性 | Easily absorbing moisture |
外观 | 白色结晶 |
MDL号 | MFCD00017416 |
体外研究 | The barks of Eucommia ulmoides (Eucommiae Cortex, Eucommiaceae) have been used as a traditional medicine in Korea, Japan, and China to treat hypertension, reinforce the muscles and bones, and recover the damaged liver and kidney functions. Feretoside increases expression of HSF1 by a factor of 1.214, 1.144, 1.153, 1.114, 1.159, 1.041, and 1.167 at 3 mm, respectively. |
参考资料 展开查看 | 1. [IF=4.759] Lu Wang et al."A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectr 2. [IF=3.512] Chenning Zhang et al."LC–MS-Based Qualitative Analysis and Pharmacokinetic Integration Network Pharmacology Strategy Reveals the Mechanism of Phlomis brevidentata H.W.Li Treatment of Pneumonia."Acs Omega. 2021;6(6):4495–4505 3. [IF=8.739] Hailou Zhang et al."Synergistic effects of two natural compounds of iridoids on rapid antidepressant action by up-regulating hippocampal PACAP signaling."British Journal Of Pharmacology. 2022 Mar 31 |
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