黄柏碱(游离黄柏碱)
黄柏碱(Phellodendrine chloride)
CAS: 6873-13-8
化学式: C20H24NO4
| 中文名 | 黄柏碱 |
| 英文名 | Phellodendrine chloride |
| 别名 | 黄柏碱 黄柏碱(游离) 黄柏碱(对照品) 黄柏碱(标准品) 黄柏碱(游离黄柏碱) PHELLODENDRINE 黄柏碱 |
| 英文别名 | Phallodendrin OB-5 Compound Phellodendrin Phellodendrine phellodendrine Phellodendrine chloride PhellodendrineDISCONTINUED. Please see P294565 6H-Dibenzo(a,g)quinolizinium, 5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-, (7S-cis)- (7S,13aS)-2,11-dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinolinium (7S,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol |
| CAS | 6873-13-8 |
| 化学式 | C20H24NO4 |
| 分子量 | 342.413 |
| InChI | InChI=1/C20H23NO4/c1-21-5-4-12-8-19(24-2)18(23)10-15(12)16(21)6-13-7-17(22)20(25-3)9-14(13)11-21/h7-10,16H,4-6,11H2,1-3H3,(H-,22,23)/p+1/t16-,21-/m0/s1 |
| 熔点 | >213°C (dec.) |
| 溶解度 | DMSO (微溶)，甲醇 (微溶，加热) |
| 存储条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 稳定性 | 吸湿性 |
| 外观 | 固体 |
| 颜色 | White to Off-White |
| 物化性质 | 来源于芸香科植物黄柏的树皮；威氏黄柏的茎皮 |
| 参考资料 展开查看 | 1. 邹静 陈慧 彭懿 等. HPLC法同时测定加味二妙颗粒中7种成分及指纹图谱建立[J]. 中成药 2018 v.40(02):99-104. 2. 徐芳芳,张秀莉,侯滔,曲腊腊,王纪霞,刘艳芳,梁鑫淼.天然产物中FFA1受体新激动剂的发现与研究[J].上海中医药大学学报,2021,35(01):12-19.[4]宫梦琪,孙倩,李振.天麻中天麻素提取工艺优化及抑制α-葡萄糖苷酶活性研究[J].中国果菜,2020,40(09):14-17+23. 3. Yue, Xiao, et al. "Berberine activates bitter taste responses of enteroendocrine STC-1 cells." Molecular and cellular biochemistry 447.1 (2018): 21-32.https://doi.org/10.1007/s11010-018-3290-3 4. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https:// 5. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606 6. [IF=3.396] Liang Jie et al."Expression and functional activity of bitter taste receptors in primary renal tubular epithelial cells and M-1 cells."Mol Cell Biochem. 2017 Apr;428(1):193-202 7. [IF=2.795] Yue Xiao et al."Berberine activates bitter taste responses of enteroendocrine STC-1 cells."Mol Cell Biochem. 2018 Oct;447(1):21-32 8. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820 |
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