中文名 | 黄芪多糖 |
英文名 | Astragalus polysaccharide |
别名 | 黄芪多糖 示差检测 |
英文别名 | ASTRAGALUS ROOT RGBRM Asrtga JUS polysacch ride Astragalus polysaccharide Astragali Polysaccharoses |
CAS | 89250-26-0 |
EINECS | 2017-001-1 |
化学式 | 混合物 |
密度 | 1.439 |
熔点 | 154.5 °C |
沸点 | 406.2±30.0 °C(Predicted) |
存储条件 | 2-8℃ |
外观 | 白色粉末 |
MDL号 | MFCD02180551 |
风险术语 | R34 - 引起灼伤。 |
安全术语 | S22 - 切勿吸入粉尘。 S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 |
参考资料 展开查看 | 1. 常兴,张庆祥,刘燕,颜培正,孟庆岩.基于“肺阳虚”理论探析温阳化饮方对哮喘寒饮蕴肺证细胞自噬的作用机制[J].中华中医药杂志,2020,35(02):650-654. 2. 刘丹,李杨,王雪林,王彦君,马寅瑞,陈彦文,明海霞.黄芪多糖(APS)及联合顺铂(DDP)抑制小鼠Lewis肺癌复发瘤生长的机制[J].细胞与分子免疫学杂志,2018,34(12):1105-1110. 3. 叶妮, 马金昀, 程晓东. 黄芪多糖对C17.2神经干细胞定向分化的调控作用[J]. 世界中医药, 2019(10). 4. 李程豪, 任春贞, 刘永琦,等. 黄芪多糖对IL-6和TNF-α模拟炎性微环境中BMSCs增殖及TAFs分化的影响[J]. 中华中医药杂志, 2018, 033(007):3039-3042. 5. 王磊,许小敏,张艳辉,刘永琦,张利英,何进鹏,冯秀,危文俊,华君瑞,王兵.黄芪多糖对X线辐射所致骨髓间充质干细胞细胞核、染色体及DNA损伤的影响[J].中国肿瘤,2018,27(09):708-714. 6. 王磊,卢志伟,许小敏,刘永琦,张利英,张苡铭,张丽昕,何进鹏,丁楠.黄芪多糖对X线辐射骨髓间充质干细胞向成骨方向分化的影响[J].中国中医药信息杂志,2017,24(12):47-51. 7. 魏孔熙, 刘永琦, 李洋洋,等. 黄芪多糖对X线辐射骨髓间充质干细胞成脂分化的影响[J]. 西安交通大学学报(医学版), 2020, 041(002):304-308. 8. 柳立军, 马鹏程, 王磊,等. 黄芪多糖对人精子冷冻后DNA完整性的保护作用[J]. 国际生殖健康/计划生育杂志, 2015(5):361-363. 9. 柳立军, 马鹏程, 张爱萍,等. 黄芪多糖对人精子冻存质量保护作用的研究[J]. 时珍国医国药, 2015, 26(10):2386-2387. 10. 伍志伟, 刘丹, 薛娜,等. 黄芪多糖对低氧环境中BMSCs成骨分化的影响[J]. 中国细胞生物学学报, 2017(06):732-738. 11. 韩亚琨, 于程程. 黄芪多糖对实验性牙周炎骨吸收的影响[J]. 中草药, 2019, 50(02):423-427. 12. 李杨, 杨玲玲, 白彦丽,等. 黄芪多糖对支气管哮喘模型小鼠气道炎症及水通道蛋白5表达的影响[J]. 甘肃中医学院学报, 2018(3). 13. 骆亚莉,张利英,李程豪,张艳辉,刘永琦,安方玉,冯彩琴,李研.黄芪多糖对炎性微环境中BMSCs的IL-6R、TNFR及肿瘤相关基因表达的影响[J].中国细胞生物学学报,2018,40(11):1819-1831. 14. 胡传活, 许春荣, 陆媚,等. 黄芪多糖对猪精液低温保存的影响[J]. 中国兽医学报, 2015, 35(1):150-154. 15. 卢志伟. 黄芪多糖对电离辐射骨髓间充质干细胞向神经分化潜能的影响[J]. 中国药理学通报, 33(07):950-955. 16. 侯赛红, 孙树芹, 徐万群,等. 黄芪多糖对糖尿病心肌病大鼠心肌细胞凋亡的影响[J]. 青岛大学学报(医学版), 2020, v.56;No.206(03):46-49. 17. 王丽帆, 丁香, 左涌丽,等. 黄芪多糖对肌源性干细胞Wnt信号相关基因表达的影响[J]. 时珍国医国药, 2017(07):1562-1564. 18. 武有明, 张齐, 刘永琦,等. 黄芪多糖对肺癌微环境中BMSCs增殖及TAFs分化的影响[J]. 中药药理与临床, 2015, 031(006):76-79. 19. 张利英, 王磊, 张丽昕,等. 黄芪多糖对重离子辐射BMSCs防护作用及与NF-κB相关机制研究[J]. 中华中医药杂志, 2018, 033(012):5576-5580. 20. 张艳辉,骆亚莉,刘永琦,王磊,许小敏,冯彩琴,李研.黄芪多糖对骨髓间充质干细胞向肿瘤相关成纤维细胞分化中IL-6/STAT3、TNF-α/NF-κB通路的影响[J].中国中医药信息杂志,2018,25(10):54-59. 21. 王雪林,李杨,刘丹,王彦君,明海霞.黄芪多糖对黄嘌呤氧化酶诱导的肺癌A549细胞自噬及PI3K/AKT信号通路的影响[J].中国药理学通报,2019,35(12):1676-1680. 22. 李琴, 李言, 高珊珊,等. 黄芪多糖抑制血管紧张素Ⅱ诱导心肌肥大的作用途径[J]. 中国组织工程研究, 2019, 23(19):3086-3091. 23. 王雪林,李杨,刘丹,王彦君,明海霞.黄芪多糖抑制黄嘌呤氧化酶诱导的肺癌A549细胞自噬并调节自噬相关蛋白的表达[J].细胞与分子免疫学杂志,2019,35(07):619-624. 24. 蒋静雯, 于颖, 蒋远飞,等. 黄芪多糖联合阿霉素肝靶向脂质体制备及抗肝癌作用[J]. 世界最新医学信息文摘, 2018, 18(98):221-222. 25. 庄梦婕,刘丹,陈彦文,明海霞.黄芪多糖联合顺铂对小鼠Lewis肺癌移植瘤Caspase-3、Smac/Diablo表达的影响[J].解剖学报,2018,49(01):63-69. 26. 庄梦婕, 刘丹, 陈彦文,等. 黄芪多糖联合顺铂抑制小鼠Lewis肺癌移植瘤生长及其机制[J]. 细胞与分子免疫学杂志, 2017(4). 27. 刘少静, 盛耀光, 康冬妮,等. 黄芪多糖脂质体的制备及其性能评价[J]. 现代中药研究与实践, 2018, 032(003):54-57. 28. 李勇森,韩孟伊,陈冰霞,张梦欣,张杰森,金晨曦,齐艳伟.黄芪对小鼠淋巴细胞及其表面分子的调节作用[J].免疫学杂志,2020,36(01):52-57. 29. 朱嵩岳, 伯乐, 杨光照,等. 黄芪改善衰老小鼠生殖功能的抗氧化机制研究[J]. 中国药业 2020年29卷13期, 44-47页, ISTIC CA, 2020. 30. [IF=3.06] Ruixin Zhang et al."Astragalus Polysaccharide Improves Insulin Sensitivity via AMPK Activation in 3T3-L1 Adipocytes."Molecules. 2018 Oct;23(10):2711 31. [IF=1.146] Han Gao et al."Proliferation and committed differentiation into dopamine neurons of neural stem cells induced by the active ingredients of radix astragali."Neuroreport. 2018 May 2; 29(7): 577–582 32. [IF=0.938] Lie Zheng et al."Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells."Open Life Sci. 2019 Jan;14(1):494-501 33. [IF=6.716] Guiqing Ding et al."Immunosuppressive activity is attenuated by Astragalus polysaccharides through remodeling the gut microenvironment in melanoma mice."Cancer Sci. 2021 Oct; 112(10): 4050–4063 34. [IF=6.419] Bingjie Wang et al."Novel nano-pomegranates based on astragalus polysaccharides for targeting ERα-positive breast cancer and multidrug resistance."Drug Deliv. 2020;27(1):607-621 35. [IF=5.81] Mao Zhu-Jun et al."Combined Use of Astragalus Polysaccharide and Berberine Attenuates Insulin Resistance in IR-HepG2 Cells via Regulation of the Gluconeogenesis Signaling Pathway."Front Pharmacol. 2019 Dec;0:1508 36. [IF=4.101] Rui Zhang et al."Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation."Int J Mol Med. 2020 Jul;46(1):331-339 37. [IF=3.848] Cao Yuxin et al."Astragalus polysaccharide regulates brown adipogenic differentiation through miR-1258-5p-modulated cut-like homeobox 1 expression."Acta Bioch Bioph Sin. 2021 Oct;: 38. [IF=3.699] Yi-Ming Zhang et al."Astragalus polysaccharide inhibits radiation-induced bystander effects by regulating apoptosis in Bone Mesenchymal Stem Cells (BMSCs)."Cell Cycle. 2020;19(22):3195-3207 39. [IF=3.682] Li-Ying Zhang et al."Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF-βR/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs."Am J Chinese Med. 2019 May;47(03):595-612 40. [IF=3.562] Jie Sun et al."APS could potentially activate hepatic insulin signaling in HFD-induced IR mice."J Mol Endocrinol. 2019 Jul;63(1):77-91 41. [IF=3.298] Guangben Wei et al."Immune effect of Vibrio harveyi formalin-killed cells vaccine combined with chitosan oligosaccharide and astragalus polysaccharides in ♀Epinephelus fuscoguttatus×♂Epinephelus lanceolatus."Fish Shellfish Immun. 2020 Mar;98:186 42. [IF=3.252] Ni Ye et al."Remyelination is enhanced by Astragalus polysaccharides through inducing the differentiation of oligodendrocytes from neural stem cells in cuprizone model of demyelination."Brain Res. 2021 Jul;1763:147459 43. [IF=2.984] Min Lin et al."lncRNA–mRNA competing endogenous RNA network in IR-hepG2 cells ameliorated by APBBR decreasing ROS levels: a systematic analysis."Peerj. 2020 Feb;8:e8604 44. [IF=2.752] Hongtao Wang et al."Effects of Apigenin and Astragalus Polysaccharide on the Cryopreservation of Bull Semen."Animals-Basel. 2021 Jun;11(6):1506 45. [IF=2.744] Shen-Yao Zhang et al."Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of femoral head through miR-206/HIF-1α/BNIP3 axis."Kaohsiung Journal Of Medical Sciences. 2021 Aug 02 46. [IF=2.629] Yang Fujia et al."Extension of Drosophila Lifespan by Astragalus polysaccharide through a Mechanism Dependent on Antioxidant and Insulin/IGF-1 Signaling."Evid-Based Compl Alt. 2021;2021:6686748 47. [IF=2.447] Shibin Feng et al."Astragalus polysaccharide enhances the immune function of RAW264.7 macrophages via the NF‑κB p65/MAPK signaling pathway."Exp Ther Med. 2021 Jan;21(1):1-1 48. [IF=1.98] Yue-Mei Zhang et al."The Effects of Astragalus Polysaccharide on Bone Marrow-Derived Mesenchymal Stem Cell Proliferation and Morphology Induced by A549 Lung Cancer Cells."Med Sci Monitor. 2019; 25: 4110–4121 49. [IF=2.629] Shi Liqing et al."Effects of Astragalus Polysaccharides on CD8+ Tissue-Resident Memory T Cells in Mice with Herpes Simplex."Evid-Based Compl Alt. 2022;2022:7729136 |
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