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中文名 | RepSox |
英文名 | RepSox |
别名 | ALK5抑制剂;ALK5抑制剂II;TGFΒR-1和ALK5抑制剂(REPSOX);2-3-(6-甲基-2-吡啶基)-1H-吡唑-4-基-1,5-萘;2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶;2-(3-(6-甲基吡啶-2-基)-1H-吡唑-4-基)-1,5-萘啶;2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶(ALK-5) |
CAS | 446859-33-2 |
EINECS | |
化学式 | C17H13N5 |
分子量 | 287.32 |
inchi | |
包装信息 | 50 mg |
价格 | $199 |
产品描述 | RepSox ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. |
产品链接 | https://www.bocsci.com/repsox-cas-446859-33-2-item-68993.html |
更新日期 | 2025-04-30 11:27:47 |