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Supplier Name | BOC Sciences |
Contact | Linna Green |
Tel | +16314854226 |
Mobile | +16314854226 |
info@bocsci.com | |
Website | https://www.bocsci.com/ |
https://www.linkedin.com/company/boc-sciences |
Product Name | RepSox |
Synonyms | RepSox E616452 SJN 2511 E-616452 ONO-7701 E 616452 ALK5 INHIBITOR I |
CAS | 446859-33-2 |
EINECS | |
Chemical Formula | C17H13N5 |
Molecular Weight | 287.32 |
inchi | |
Package | 50 mg |
Price | $199 |
Descriptions | ALK5 Inhibitor II hydrochloride ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. |
Supplier Website | https://www.bocsci.com/repsox-cas-446859-33-2-item-68993.html |
Last Update | 2025-04-30 11:27:47 |