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Supplier Contact

Supplier NameBOC Sciences
ContactLinna Green
Tel+16314854226
Mobile+16314854226
QQ
Emailinfo@bocsci.com
Websitehttps://www.bocsci.com/
Wechat
LinkedInhttps://www.linkedin.com/company/boc-sciences
Product NameRepSox
SynonymsRepSox
E616452
SJN 2511
E-616452
ONO-7701
E 616452
ALK5 INHIBITOR I

Synonyms

RepSox
E616452
SJN 2511
E-616452
ONO-7701
E 616452
ALK5 INHIBITOR I
2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE
2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
CAS446859-33-2
EINECS
Chemical FormulaC17H13N5
Molecular Weight287.32
inchi
Package50 mg
Price$199
DescriptionsALK5 Inhibitor II hydrochloride
ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form.
Supplier Websitehttps://www.bocsci.com/repsox-cas-446859-33-2-item-68993.html
Last Update2025-04-30 11:27:47
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