An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity.
An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity.
Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity
Minoxidil sulfate is the active metabolite of Minoxidil and it is a potent vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.
Milrinone is a phosphodiesterase 3 (PDE3) inhibitor with vasodilator properties, used to increase the heart's contractility. It increases erythrocyte cAMP activity via inhibiting erythrocyte phosphodiesterase.
Milciclib is an orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity. CDK2/TRKA inhibitor PHA-848125 AC potently inhibits cyclin-dependent kinase 2 (CDK2) and exhibits activity against other CDKs including CDK1 and CDK4, in addition to TRKA. Inhibition of these kinases may result in cell cycle arrest and apoptosis of tumor cells that express these kinases. CDKs are serine/threonine kinases involved in regulation of the cell cycle and may be overexpressed in some cancer cell types. The neurotrophin receptor TRKA is mutated in a variety of cancer cell types.
Miglustat HCl is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). It also inhibits glucosidase I and II, as well as HIV-1 and HIV-2 infection of peripheral blood mononuclear cells (PBMCs).
A phenylalkanolamine derivative which has been found to be effective in treating hypertensive conditions due to their long lasting blood pressure increasing effects.
Micafungin Impurity H is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.
An impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.
Micafungin Impurity E is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.
MIBG hemisulfate is a radiopharmaceutical used in a scintigraphy method called MIBG scan. It demethylates and oxidizes membrane-associated DNA for the treatment of certain kinds of cancer of the adrenal glands.
Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA) and has antidepressant, anxiolytic (anti-anxiety), hypnotic (sedating), antiemetic (nausea and vomiting-attenuating), orexigenic (appetite-stimulating), and antihistamine effects.It is not approved for use in the US.
MGL-3196 is a first-in-class, orally available, once-daily and liver-directed thyroid hormone receptor (THR) beta-selective agonist. Studies suggest that MGL-3196 has an attractive, differentiated profile as a potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias.
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.
Meisoindigo is a derivative of indirubin with antitumor activity, which has been used in China for chronic myeloid leukemia. Meisoindigo is an apoptosis inducer and potential agent for the treatment of AML. It inhibits the growth of leukemic cells by inducing marked apoptosis and moderate cell-cycle arrest at the G(0)/G(1) phase.
Methylene calcitriol is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood.
Methyl S-(acetamidomethyl)-L-cysteinate monohydrochloride, a formidable antioxidant, holds vast potential in the biomedicine realm, particularly cardiac ailment treatment. Its employment in predominantly combating hypertension and atherosclerosis makes it an indispensable option for pharmaceutical development.
Methyl perfluoroisobutyl ether is an indispensable fluorinated solvent utilized in the biomedical industry, providing efficient extraction and purification of numerous drugs and biomolecules. Furthermore, its exceptional features, as a highly fluorinated and inert compound, present potential as a key player in the development of treatments against diseases such as cancer and respiratory illnesses. Its application in multiple biological processes, owed to its unique properties, cements its critical role in biomedical research and experimentation.
Methyl Olivetolate is an intermediate in the synthesis of Δ9-Tetrahydrocannabinolic Acid, the biosynthetic precursor of delta-9-tetrahydrocannabinol (THC) in cannabis plants, and has no psychotropic effects.
Methyl N-acetyl-2-deoxy-α-D-galactosamine is a crucial compound in biomedicine. It is extensively utilized for researching glycosylation and treating diseases related to abnormal glycosylation, such as congenital disorders of glycosylation (CDGs). With its molecular structure and composition, Methyl N-acetyl-2-deoxy-α-D-galactosamine proves valuable in elucidating glycan function and developing potential therapeutic interventions.
Methyl b-D-glucuronide sodium salt is a chemical compound used in the biomedical industry for its role in drug metabolism studies. It is commonly employed as a substrate to evaluate glucuronidation reactions mediated by glucuronosyltransferase enzymes. This product aids in understanding drug metabolism and its implications in treating various diseases by facilitating the study of drug elimination pathways.
Methyl 5-Acetamido-7,8,9-tri-O-acetyl-5-N,4-O-carbonyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glycero-b-D-galacto-2-nonulopyranosylonate, a chemical entity of paramount importance in pharmaceutical studies. This compound plays a key role in antiviral drug development, primarily focusing on HIV reverse transcriptase and integrase. Moreover, it exhibits inhibitory activity against an array of viruses, including Ebola and Zika, which presents a profound scope for therapeutic interventions.
