Naronapride is a selective 5-HT(4) receptor agonist for gastrointestinal motility disorders. It can accelerate overall colonic transit and tend to accelerate GE and AC emptying and loose stool consistency. In Nov 2016, Renexxion planed two phase III trials for Constipation in USA.
Naringin Dihydrochalcone (Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.
Naringenin chalcone is a natural chalconoid that can be isolated from tomato skin. It exhibits antioxidant, anti-inflammatory, and anti-allergic properties.
Narciclasine, which can be found in the tubers of Narcissus tazetta, displays marked proapoptotic and cytotoxic activity, as does pancratistatin, and significant in vivo anticancer effects in various experimental models. It is a potential agent for the treatment of primary brain cancers and various brain metastases.
Naquotinib is an irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity with IC50 of 8-33 nM toward EGFR mutants.
N-Allylurea is a compound that functions as a precursor in the synthesis of various organic compounds. It acts as a reactant in the production of polymers and agrochemicals.
N-Allylmaleimide, a compound with biomedical research applications, boasts an inhibitory prowess for the growth of select cancer cells. In addition, studies have revealed its potential neuroprotective attributes, making it a promising candidate for neurodegenerative disease treatment. Surmised to exert its effects via hindrance of protein-protein associations, this agent exhibits dynamic impact on applicable systems.
NADPH tetrasodium salt is an ubiquitous coenzyme that acts as an electron donor in various biological reactions. Nutritional supplement in health care products.
Sodium salt hydrate form of NADP which is a coenzyme widely exist in living organism and commonly related to oxidation-reduction reactions. Nutritional supplement in health care products.
NADP disodium salt, also called as Coenzyme II, widely distributed in living matter, is a participant coenzyme in aerobic and anaerobic oxidations. Nutritional supplement in health care products.
NADH becomes oxidized to produce NAD+, NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain. Nutritional supplement in health care products.
Nacubactam is a beta-lactamase inhibitor used for treating bacterial infections. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs.
N-Acetyl-β-neuraminic acid methyl ester is an indispensable compound widely renowned for its capability to imitate sialic acid. This methyl ester derivative showcases an extensive array of applications in the research of diverse ailments such as cancer, neurodegenerative disorders and viral infections.
N-Acetyl-α-D-glucosamine-1-phosphate disodium salt is an indispensable compound in the biomedical sector with applications extending to studying an array of diseases and conditions, including particular enzyme deficiencies and genetic disorders.
N-Acetyl-L-cysteine ethyl ester, a derivative of N-acetylcysteine, is acknowledged for its highly efficacious anti-inflammatory and antioxidant properties. This potent compound has been employed in numerous treatments, including those for cystic fibrosis and HIV-associated neuropathy. Apart from that, it is widely consumed as a dietary supplement due to its potentiality in enhancing liver and lung health.
N-acetyldopamine, an organic chemical compound, exhibits significant therapeutic potential in various neurodegenerative disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), and depression. It has been extensively researched for its ability to act as an antioxidant and anti-inflammatory agent, enabling it to provide effective treatment against a host of oxidative stress disorders. Its clinical efficacy in treating these complex neurological conditions has made it a valuable compound in pharmaceutical research, with an ever-increasing scientific interest in unlocking its potential benefits.
N-Acetyldesloratadine is an effective and orally active dual antagonist of platelet-activating factor and histamine. N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine.
N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is used to incorporate 2-O-methyl modified nucleotides into oligonucleotides. It is a novel nucleoside analogue drug that inhibits tumor growth and activates RNA polymerase II promoter transcription.
N-Acetyl-3-iodo-L-tyrosine hemihydrate, a chemical reagent with notable significance in studying enzyme inhibitors and protein synthesis, is widely utilized in the medical research community to develop promising drug therapies for thyroid disorders and cancers. Such compounds may also be used to synthesize radioiodinated compounds, essential in the realm of medical imaging and diagnostics.
N-Acetyl Sitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2.
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4.
N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE-phosphoramidite is an antiviral agent that inhibits the replication of DNA.
N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified A into oligonucleotide phosphoramidites, which is useful for antisense RNA. The 2'-MOE backbone provides stronger duplex stability, significant nuclease resistance and relatively low toxicity.
N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite can be used to incorporate 2-fluoro modified nucleotides into oligonucleotides, improving metabolic stability.
N6-(cis-hydroxyisopentenyl)adenosine is a remarkable biochemical compound, used for studying an array of ailments and circumstances including breast and lung cancer. Swiftly, it embraces anti-inflammatory traits thus used for studying diseases of inflammation, particularly the notorious rheumatoid arthritis.
N4-benzoyl-5'-O-tert-Butyldimethylsilyl-2'-deoxycytidine, a potent antitumor agent, offers therapy for an array of cancers like metastatic breast cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Its mechanism of action involves inhibiting DNA synthesis by interrupting the replication of DNA strands. By integrating itself into these strands, it results in premature chain termination. The compound thus offers a promising avenue for cancer therapy.
N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine, an influential antiviral agent extensively employed in the biomedical sector, showcases remarkable efficacy in combating RNA viral infections. Its valuable contributions lie in its capacity to combat diverse viral strains, thereby enlightening researchers on viral replication processes and fostering the advancement of groundbreaking antiviral treatments.
N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is widely used in the biomedical industry as a building block for synthesizing modified nucleotides. It plays a crucial role in the research of pharmaceutical drugs targeting specific diseases, such as cancer and viral infections.
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite is an indispensable compound within the biomedical domain with widespread application as a phosphoramidite constituent during oligonucleotide synthesis, primarily in the research of antisense therapy and gene silencing.
N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, a fundamental component in the field of biomedical research, plays a vital role in the synthesis of modified nucleotides. This indispensable compound finds wide applicability in the creation and investigation of nucleic acid-derived pharmaceuticals, with particular focus on the exploration and mitigation of viral infections, malignancies, and hereditary anomalies.
3-MethylpseudoUridine is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival.
N2-iso-Butyroyl-7'-O-(4,4'-dimethoxytrityloxy)morpholinoguanine, an exceedingly powerful and discriminating inhibitor, finds application in the management of an array of malignancies. By selectively targeting enzymatic entities implicated in the proliferation of neoplastic cells, it stifles their functional kinetics and thereby curtails the growth of malignant tumors.
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine, a biomedical compound, demonstrates its effectiveness in targeting and treating specific diseases. Its therapeutic potential and precise mechanism of action can be explored through the referenced websites, providing comprehensive information concerning drug interactions and its efficacy in addressing various medical conditions.
N2-iso-Butyroyl-3'-O-methylguanosine - a valuable tool for biomedicine exploration. This organic compound finds frequent utility in mRNA synthesis, the development of capping analogs and high-affinity RNA aptamers. Its worth extends beyond these applications, with capabilities to examine structural and functional elements of mRNA capping enzymes.
N2-iso-Butyroyl-3'-deoxy-3'-fluoroguanosine, a crucial compound in the field of biomedicine, showcases its potency as an effective antiviral agent targeted at treating viral infections resulting from the influenza virus. By virtue of its distinct chemical characteristics, it displays remarkable capability in hindering viral replication and alleviating the severity of influenza-related symptoms.
An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA.
N2,N2,N7-Trimethylguanosine, an indispensable compound employed in the biomedical sector, emerges as a key player in scientific exploration. This modified nucleoside finds widespread application in the domain of research and development. In unraveling the intricacies of m6A mRNA methylation, RNA modification, and RNA metabolism, it assumes a pivotal role. With N2,N2,N7-Trimethylguanosine at their disposal, researchers gain unprecedented insights into the multifaceted realms of drug analysis, disease examination, and the mechanisms governing RNA processing, regulation, and translation.
It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination.
