奈拉西坦
NEBRACETAM
CAS: 116041-13-5
Molecular Formula: C12H16N2O
奈拉西坦 - Names and Identifiers
| Name | NEBRACETAM |
| Synonyms | WEB-1881 NEBRACETAM WEB-1881FU Nebracetamum Unii-T30038qi8n Nebracetamum [inn-latin] (±)-4-(Aminomethyl)-1-(phenylmethyl)-2-pyrrolidinone |
| CAS | 116041-13-5 |
奈拉西坦 - Physico-chemical Properties
| Molecular Formula | C12H16N2O |
| Molar Mass | 204.271 |
| Physical and Chemical Properties | Chemical Properties Nairacetam Fumarate (Nebracetam Fumarate):(C12H16N2O)2?C4H4O4. [97205-35-1]. Crystallization, melting point 192~194 ℃. Acute toxicity LD50 male and female rats (mg/kg):257,257 intravenous injection; 2884,3622 oral. |
| Use | Use of nootropic drugs. It has a cholinergic effect and has an affinity for cholinergic receptors, especially for M1, the receptor. |
奈拉西坦 - Upstream Downstream Industry
| Raw Materials | Fumaric acid |
奈拉西坦 - Production method
Method 1: Compound (I) and thionyl chloride are refluxed in methylene chloride to form chloride (II). Then it is condensed with potassium phthalamide in dimethylformamide, and the product (III) is reduced with hydrazine in ethanol to obtain nelacetam, which is neutralized with fumaric acid to obtain nelacetam fumarate.
Method 2: Compound (Ⅳ) is reacted with phosphorus oxychloride in hot dimethylformamide to dehydrate to obtain nitrile (V), and then hydrogenated and reduced under the catalysis of Raney nickel in ammonia-methanol mixture to obtain nelacetam, and neutralized with fumaric acid to obtain nelacetam fumarate.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: NEBRACETAM Visit Supplier Webpage Request for quotationCAS: 116041-13-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History
奈拉西坦
2,6-二[(4R)-4-苄基-2-噁唑啉-2-基]吡啶
Sulfonium, [2-(3-bromophenyl)ethyl]dimethyl-, bromide (1:1)
Oprea1_250041
Ceftizoxime Impurity 19
(1S,3S,5S)-2-氮杂双环[3.1.0]己烷-3-羧酰胺甲烷磺酸盐
3-甲氧基氮杂环丁烷盐酸盐
1-methyl-4-picoliniuiodide
4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER
REACTIVE RED 194
2,6-二[(4R)-4-苄基-2-噁唑啉-2-基]吡啶
Sulfonium, [2-(3-bromophenyl)ethyl]dimethyl-, bromide (1:1)
Oprea1_250041
Ceftizoxime Impurity 19
(1S,3S,5S)-2-氮杂双环[3.1.0]己烷-3-羧酰胺甲烷磺酸盐
3-甲氧基氮杂环丁烷盐酸盐
1-methyl-4-picoliniuiodide
4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID PINACOL ESTER
REACTIVE RED 194
Raw Materials for 奈拉西坦