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Nebracetamum

NEBRACETAM

CAS: 116041-13-5

Molecular Formula: C12H16N2O

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Nebracetamum - Names and Identifiers

Name NEBRACETAM
Synonyms WEB-1881
NEBRACETAM
WEB-1881FU
Nebracetamum
Unii-T30038qi8n
Nebracetamum [inn-latin]
(±)-4-(Aminomethyl)-1-(phenylmethyl)-2-pyrrolidinone
CAS 116041-13-5

Nebracetamum - Physico-chemical Properties

Molecular FormulaC12H16N2O
Molar Mass204.271
Physical and Chemical PropertiesChemical Properties Nairacetam Fumarate (Nebracetam Fumarate):(C12H16N2O)2?C4H4O4. [97205-35-1]. Crystallization, melting point 192~194 ℃. Acute toxicity LD50 male and female rats (mg/kg):257,257 intravenous injection; 2884,3622 oral.
UseUse of nootropic drugs. It has a cholinergic effect and has an affinity for cholinergic receptors, especially for M1, the receptor.

Nebracetamum - Upstream Downstream Industry

Raw MaterialsFumaric acid

Nebracetamum - Production method

Method 1: Compound (I) and thionyl chloride are refluxed in methylene chloride to form chloride (II). Then it is condensed with potassium phthalamide in dimethylformamide, and the product (III) is reduced with hydrazine in ethanol to obtain nelacetam, which is neutralized with fumaric acid to obtain nelacetam fumarate.
Method 2: Compound (Ⅳ) is reacted with phosphorus oxychloride in hot dimethylformamide to dehydrate to obtain nitrile (V), and then hydrogenated and reduced under the catalysis of Raney nickel in ammonia-methanol mixture to obtain nelacetam, and neutralized with fumaric acid to obtain nelacetam fumarate.

Last Update:2024-04-10 22:29:15
Supplier List
SKYRUN INDUSTRIAL CO.,LTD
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CAS: 116041-13-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
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SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: NEBRACETAM Visit Supplier Webpage Request for quotation
CAS: 116041-13-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
View History
Nebracetamum
15118-67-9
4-hydroxy-3,4-dihydrocyclopenta(cd)pyrene
盐酸间苯二胺
17334-08-6
突厥烯酮标准品
134419-41-3
屠锈胺
Raw Materials for Nebracetamum
Fumaric acid
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