(-)-(S)-1-(p-Hydroxyphenoxy)-3-(isopropylamino)-2-propanol
Prenalterol
CAS: 57526-81-5
Molecular Formula: C12H19NO3
(-)-(S)-1-(p-Hydroxyphenoxy)-3-(isopropylamino)-2-propanol - Names and Identifiers
(-)-(S)-1-(p-Hydroxyphenoxy)-3-(isopropylamino)-2-propanol - Physico-chemical Properties
| Molecular Formula | C12H19NO3 |
| Molar Mass | 225.28 |
| Density | 1.118 |
| Melting Point | 127-128° |
| Boling Point | 398℃ |
| Specific Rotation(α) | D20 -1 ±1°; 20Hg +2 ±1° (c = 0.940 in methanol) |
| Flash Point | 194℃ |
| Solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 4.86E-07mmHg at 25°C |
| Appearance | Solid |
| Color | Off-White to Beige |
| pKa | pKa 9.5 (Uncertain);10.0 (Uncertain) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.538 |
(-)-(S)-1-(p-Hydroxyphenoxy)-3-(isopropylamino)-2-propanol - Introduction
Prenalterol(Prenalterol) is a non-selective β-adrenergic receptor agonist with inotropic and positive inotropic effects. It can activate the heart beta 1 receptor and expand the coronary arteries, thereby increasing the contractility of the heart and reducing vascular resistance, promoting the contraction and relaxation of the heart.
Prenalterol is mainly used to treat heart failure, especially congestive heart failure. It can increase cardiac output, improve myocardial contractility, and reduce the load on the heart. In addition, it can also be used in supportive shock and to treat conditions that require increased myocardial contractility.
The preparation method of Prenalterol is mainly obtained by reacting paracetamol with 3,5-dimethyl-4-hydroxypyridine. The specific synthesis process can be carried out in the laboratory.
When using Prenalterol, you need to pay attention to the following safety information: For patients with vasoconstrictive diseases, hyperthyroidism, abnormal heart rhythm, etc., Prenalterol use may increase the burden on the heart and cause adverse reactions. There is a lack of safety data for pregnant women, lactating women, and children, so caution is required for use in these populations. In addition, Prenalterol may cause some common side effects, such as palpitations, headaches, elevated blood pressure, etc. If there are serious adverse reactions, the drug should be stopped immediately and a doctor should be consulted.
Prenalterol is mainly used to treat heart failure, especially congestive heart failure. It can increase cardiac output, improve myocardial contractility, and reduce the load on the heart. In addition, it can also be used in supportive shock and to treat conditions that require increased myocardial contractility.
The preparation method of Prenalterol is mainly obtained by reacting paracetamol with 3,5-dimethyl-4-hydroxypyridine. The specific synthesis process can be carried out in the laboratory.
When using Prenalterol, you need to pay attention to the following safety information: For patients with vasoconstrictive diseases, hyperthyroidism, abnormal heart rhythm, etc., Prenalterol use may increase the burden on the heart and cause adverse reactions. There is a lack of safety data for pregnant women, lactating women, and children, so caution is required for use in these populations. In addition, Prenalterol may cause some common side effects, such as palpitations, headaches, elevated blood pressure, etc. If there are serious adverse reactions, the drug should be stopped immediately and a doctor should be consulted.
Last Update：2024-04-09 20:52:54
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Product Name: Prenalterol Visit Supplier Webpage Request for quotation
CAS: 57526-81-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 57526-81-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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