(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate
CAS: 187682-63-9
Molecular Formula: C27H40F3O3P2RhS
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate - Names and Identifiers
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate - Physico-chemical Properties
| Molecular Formula | C27H40F3O3P2RhS |
| Molar Mass | 666.52 |
| Appearance | crystal |
| Color | orange |
| Sensitive | air sensitive, store cold |
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate - Introduction
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate is an organometallic compound with the chemical formula [C26H38O3P2Rh(C8H12)][CF3SO3]. The following describes its nature, use, preparation and safety information:
Nature:
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate is a homogeneous catalyst, commonly orange crystals. It has a symmetrical chiral structure and can catalyze enantioselective reactions without relying on external chiral auxiliaries.
Use:
The compound is widely used in the field of organic synthesis, mainly for asymmetric synthesis reactions. It can be used for catalytic asymmetric carbonylation, asymmetric hydrogenation, asymmetric cycloaddition, and cycloaddition of asymmetric alkenes to alkynes. Because of its good performance of enantioselectivity and catalytic effect, it is widely used in the preparation of chiral drugs and the synthesis of bioactive molecules.
Preparation Method:
A common method of preparation is by chemical synthesis. In general, the target product is obtained by reacting the corresponding ligand with [Rh(COD)Cl]2 (wherein, COD represents cyclooctadiene), and then reacting with trifluoromethanesulfonic acid.
Safety Information:
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate relatively little safety information. Because it is an organometallic compound, it has certain safety measures and needs to be stored and handled under appropriate conditions. Such compounds should be handled in accordance with chemical safety regulations and avoid direct contact with skin, eyes or respiratory tract. For further safety information, refer to the safety data sheets of the relevant chemicals.
Nature:
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate is a homogeneous catalyst, commonly orange crystals. It has a symmetrical chiral structure and can catalyze enantioselective reactions without relying on external chiral auxiliaries.
Use:
The compound is widely used in the field of organic synthesis, mainly for asymmetric synthesis reactions. It can be used for catalytic asymmetric carbonylation, asymmetric hydrogenation, asymmetric cycloaddition, and cycloaddition of asymmetric alkenes to alkynes. Because of its good performance of enantioselectivity and catalytic effect, it is widely used in the preparation of chiral drugs and the synthesis of bioactive molecules.
Preparation Method:
A common method of preparation is by chemical synthesis. In general, the target product is obtained by reacting the corresponding ligand with [Rh(COD)Cl]2 (wherein, COD represents cyclooctadiene), and then reacting with trifluoromethanesulfonic acid.
Safety Information:
(-)-1,2-Bis((2R,5R)-2,5-dimethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I)trifluoromethanesulfonate relatively little safety information. Because it is an organometallic compound, it has certain safety measures and needs to be stored and handled under appropriate conditions. Such compounds should be handled in accordance with chemical safety regulations and avoid direct contact with skin, eyes or respiratory tract. For further safety information, refer to the safety data sheets of the relevant chemicals.
Last Update：2024-04-09 21:04:16
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