(-)-1,2-Bis((2R,5R)-2,5-diphenyL
(-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate
CAS: 528565-84-6
Molecular Formula: C42H48BF4P2Rh
(-)-1,2-Bis((2R,5R)-2,5-diphenyL - Names and Identifiers
(-)-1,2-Bis((2R,5R)-2,5-diphenyL - Physico-chemical Properties
| Molecular Formula | C42H48BF4P2Rh |
| Molar Mass | 804.49 |
| Appearance | crystal |
| Color | orange |
| Sensitive | air sensitive |
(-)-1,2-Bis((2R,5R)-2,5-diphenyL - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
(-)-1,2-Bis((2R,5R)-2,5-diphenyL - Introduction
(-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane (1,5-cycloketadiene) rhodium(I) tetrafluoroborate, also known as (-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane (1,5-cycloketadiene) is a metal tetrafluoroborate. The following are some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless crystal or powder
-Molecular formula: C44H48BF4P2Rh
-Molecular weight: 843.67g/mol
-melting point: 100-101 ℃
-Solubility: Soluble in a variety of organic solvents
Use:
-This compound is an important catalyst, widely used in organic synthesis reactions, especially the synthesis of chiral compounds.
-It has high catalytic activity in asymmetric hydrogenation reaction, asymmetric addition reaction and asymmetric catalytic reaction.
Preparation Method:
- (-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane (1,5-cycloctadiene) rhodium(I) tetrafluoroborate can be prepared by the following steps:
1. First, 1,2-dibromoethane is reacted with 1,5-cyclooctadiene to obtain 1,2-bis (1,5-cyclooctadiene) ethane.
2. It is then reacted with diphenylphosphine to obtain 1,2-bis [(2R,5R)-2,5-diphenylphosphine] ethane.
3. Finally, 1,2-bis [(2R,5R)-2,5-diphenylphosphine] ethane is reacted with rhodium tetrafluoroborate (I) to generate the target product.
Safety Information:
- (-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane (1,5-cycloctadiene) rhodium(I) tetrafluoroborate may be harmful to humans and the environment.
-Necessary safety precautions, such as wearing appropriate personal protective equipment (such as gloves, glasses, etc.).
-Avoid inhalation, ingestion or contact with skin and eyes during operation.
-The compound should be stored, handled and disposed of properly to avoid contamination and harm to the environment.
Nature:
-Appearance: colorless crystal or powder
-Molecular formula: C44H48BF4P2Rh
-Molecular weight: 843.67g/mol
-melting point: 100-101 ℃
-Solubility: Soluble in a variety of organic solvents
Use:
-This compound is an important catalyst, widely used in organic synthesis reactions, especially the synthesis of chiral compounds.
-It has high catalytic activity in asymmetric hydrogenation reaction, asymmetric addition reaction and asymmetric catalytic reaction.
Preparation Method:
- (-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane (1,5-cycloctadiene) rhodium(I) tetrafluoroborate can be prepared by the following steps:
1. First, 1,2-dibromoethane is reacted with 1,5-cyclooctadiene to obtain 1,2-bis (1,5-cyclooctadiene) ethane.
2. It is then reacted with diphenylphosphine to obtain 1,2-bis [(2R,5R)-2,5-diphenylphosphine] ethane.
3. Finally, 1,2-bis [(2R,5R)-2,5-diphenylphosphine] ethane is reacted with rhodium tetrafluoroborate (I) to generate the target product.
Safety Information:
- (-)-1,2-Bis((2R,5R)-2,5-diphenylphospholano)ethane (1,5-cycloctadiene) rhodium(I) tetrafluoroborate may be harmful to humans and the environment.
-Necessary safety precautions, such as wearing appropriate personal protective equipment (such as gloves, glasses, etc.).
-Avoid inhalation, ingestion or contact with skin and eyes during operation.
-The compound should be stored, handled and disposed of properly to avoid contamination and harm to the environment.
Last Update：2024-04-10 22:29:15
