(-)-β-Bisabolene

(-)-β-Bisabolene - Names and Identifiers

Name	(-)-β-bisabolene,β-bisabolene,6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-1,5-heptadiene
Synonyms	B-Bisabolene (-)-β-bisabolene (S)-beta-bisabolene Cyclohexene,1-methyl-4-(5- 1-Methyl-4-(6-methylhepta-1,5-dien-2-yl)-cyclohex-1-ene 6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hepta-1,5-diene [S,(-)]-1-Methyl-4-(5-methyl-1-methylene-4-hexenyl)cyclohexene Cyclohexene, 1-methyl-4-(5-methyl-1-methylene-4-hexenyl)-, (4S)- (-)-β-bisabolene,β-bisabolene,6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-1,5-heptadiene
CAS	495-61-4
EINECS	610-461-5

(-)-β-Bisabolene - Physico-chemical Properties

Molecular Formula	C15H24
Molar Mass	204.35
Density	0.8673
Boling Point	277.87°C (rough estimate)
Solubility	Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Vapor Presure	0.9-5Pa at 20-25℃
Appearance	Oil
Color	Colourless to Light Yellow
Storage Condition	Amber Vial, Refrigerator
Stability	Light Sensitive
Refractive Index	1.4880
In vitro study	β‐bisabolene exhibits selective cytotoxic activity for mouse cells, it against normal Eph4, MG1361 and 4T1 cells with IC 50 values of >200 µg/ml, 65.49 µg/ml, and 48.99 µg/ml, respectively. It against normal MCF‐10A, MCF‐7, MDA‐MB‐231, SKBR3 and BT474 cells with IC 50 values of 114.3 µg/ml, 66.91 µg/ml, 98.39 µg/ml, 70.62 µg/ml and 74.3 µg/ml, respectively.
In vivo study	β‐bisabolene is effective in reducing the growth of transplanted 4T1 mammary tumoursin vivo(37.5% reduction in volume by endpoint).

(-)-β-Bisabolene - Reference

Reference

1. [IF=7.514] Ruijie Ni et al."Effects of different frying temperatures on the aroma profiles of fried mountain pepper (Litsea cubeba (Lour.) Pers.) oils and characterization of their key odorants."Food Chem. 2021 Sep;357:129786

(-)-β-Bisabolene - References

LogP	6.5 at 23℃ and pH6.2
Introduction	β-myrcene is a colorless oily liquid that is insoluble in water and soluble in organic solvents such as ethanol. It has a warm aroma of Woody, citrus, floral, fruit, blue, and sweet balsam aroma.
Use	β-myrcene can be used to blend citrus, Orange, tropical fruit, banana, grapefruit, apple, fresh pear and other food flavors.
biological activity	β-bisabene is a sesquiterpene isolated from Paeonia lactiflora. Β-bisabolene is an anti-cancer agent that can be used in the study of breast cancer.

Last Update：2024-04-09 20:45:29