(15E)-Retrorsine - Names and Identifiers
Name | Usaramine
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Synonyms | Usaramin Usaramine Mucronatine NISTC15503874 (15E)-Retrorsine trans-Retrorsine (15E)-12,18-Dihydroxysenecionan-11,16-dione [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-,(3E,5R,6S,14aR,14bR)-
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CAS | 15503-87-4
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(15E)-Retrorsine - Physico-chemical Properties
Molecular Formula | C18H25NO6
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Molar Mass | 351.39 |
Density | 1.32±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 178-180℃ |
Boling Point | 583.2±50.0 °C(Predicted) |
Specific Rotation(α) | (c, 1.83 in EtOH)+7.1 |
Solubility | Soluble in chloroform, ethyl acetate, acetone and other solvents. |
Appearance | White crystal |
pKa | 12.00±0.40(Predicted) |
Storage Condition | 2-8℃ |
(15E)-Retrorsine - Introduction
Usaramine is a natural alkaloid, also known as photosynthetic alkaloid or Lycorine. Its chemical structure contains a ring five-membered heterocyclic ring, a ring nine-membered heterocyclic ring and a butyl eye structure. Its chemical formula is C16H17NO4 and its relative molecular mass is 299.31.
Usaramine is a light yellow crystal with a spicy and bitter taste. It is relatively stable and not easy to decompose at room temperature. Under the action of oxidants or strong acids, Usaramine can undergo diketo and dicarboxylation reactions.
Usaramine has a variety of uses in the medical field. It has antiviral, protein synthesis inhibition and antitumor activity. Studies have shown that Usaramine can fight hepatitis B virus, HIV virus and other viruses. In addition, it has an inhibitory effect on some tumor cells and can be used as a candidate compound for antitumor drugs.
The preparation method of Usaramine is more complicated, and it is usually extracted from lily plants. The main extraction methods include water extraction, organic solvent extraction and ultrasonic assisted extraction.
Regarding safety information, Usaramine has certain toxicity. High doses of Usaramine are harmful to the human body. After entering the human body, it may cause vomiting, diarrhea, central nervous system inhibition and other adverse reactions. Therefore, when using Usaramine should follow safe practices, avoid contact with the skin and inhalation of dust. In the preparation and application of Usaramine, the dosage and use environment need to be strictly controlled.
Last Update:2024-04-09 20:48:19