(1E,6E)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-dione - Names and Identifiers
Name | Demethyl Curcumin
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Synonyms | Demethyl Curcumin (1E,6E)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-dione 1,6-Heptadiene-3,5-dione, 1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-
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CAS | 149732-51-4
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(1E,6E)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-dione - Physico-chemical Properties
Molecular Formula | C20H18O6
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Molar Mass | 354.35 |
Density | 1.350±0.06 g/cm3(Predicted) |
Melting Point | 183-187°C (dec.) |
Boling Point | 617.5±55.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Orange to Dark Orange |
pKa | 8.14±0.46(Predicted) |
Storage Condition | -20°C Freezer |
(1E,6E)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-dione - Reference
Reference Show more | 1. [IF=4.946] Lai Yanni et al."3D-quantitative structure–activity relationship and antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase."Arch Pharm Res. 2020 May;43(5):489-502 |
(1E,6E)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-dione - Introduction
Demethyl Curcumin is a compound isolated from Curcumin. It is a yellow crystalline powder, odorless. Demethyl Curcumin is a derivative of Curcumin with one methyl group removed.
Demethyl Curcumin has some properties similar to Curcumin. It has good antioxidant properties, can neutralize free radicals and reduce cell damage caused by oxidative stress. In addition, it also has anti-inflammatory, anti-tumor and antibacterial activities. The study also found that Demethyl Curcumin has a potential protective effect against vascular inflammation and cardiovascular disease.
Demethyl Curcumin has potential application value in the field of medicine. It can be used to prepare products such as medicines, health products and cosmetics. Due to its multiple activities, Demethyl Curcumin is also widely used in food additives to increase the nutritional value and antioxidant capacity of food.
The preparation method of Demethyl Curcumin is generally obtained by a synthetic method. First, one methyl group is removed from Curcumin to give Demethyl Curcumin.
in the use of Demethyl curcurcumin need to pay attention to its safety. No clear toxicity information has been reported, but appropriate safe procedures for handling and use should be followed. During use, avoid inhaling dust and avoid contact with skin and eyes. If discomfort occurs, seek medical attention. Appropriate toxicity assessment and safety testing is recommended prior to use.
Last Update:2024-04-09 21:01:54