(1R)-1-(3-chroophenyl) ETHANOL ((1R)-1-(3-chroophenyl) ETHANOL) is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to yellowish liquid.
-Molecular formula and molecular weight: C8H9ClO, molecular weight 156.61g/mol.
-Melting point:-10 ° C.
-Boiling point: 226-227 ° C.
-Solubility: Soluble in ethanol, acetone and ether, slightly soluble in water.
Use:
- (1R)-1-(3-chroophenyl) ETHANOL is commonly used as a synthetic intermediate in the pharmaceutical industry and can be used to synthesize chiral drugs or related compounds.
Method:
- (1R)-1-(3-CHLOROPHENYL)ETHANOL can be prepared by the following steps:
1. Esterification of (1R)-1-acetone alcohol with 3-chlorobenzoic acid in the presence of sodium oxide to obtain (R)-1-(3-chlorophenyl) acetic acid.
2. (R)-1-(3-CHLOROPHENYL) acetic acid is reduced to give (1R)-1-(3-CHLOROPHENYL)ETHANOL.
Safety Information:
- (1R)-1-(3-CHLOROPHENYL)ETHANOL is a chemical that should be stored properly, avoiding exposure to ignition and oxidizing agents.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use.
-If you are in contact with skin or eyes, rinse immediately with plenty of water. If you feel unwell, seek medical attention.
-This is a brief safety information, please refer to the safety technical instructions of the relevant chemicals for specific safety operations.