(1R,2R,3S,5R)-(-)-Pinanediol

(1R,2R,3S,5R)-(-)-Pinanediol - Names and Identifiers

Name	(1R,2R,3S,5R)-(-)-2,3-Pinanediol
Synonyms	(-)-2-HYDROXYISOPINOCAMPHEOL (-)-2-Hydroxyisopinocampheol (1R,2R,3S,5R)-(-)-Pinanediol (1R,2R,3S,5R)-2,3-PINANEDIOL (1R,2R,3S,5R)-(-)-PINANEDIOL (1R,2R,3S,5R)-(-)-2,3-Pinanediol (1R,2R,3S,5R)-(-)-2,3-PINANEDIOL (1S,2R,3S,5S)-2,6,6-trimethylbicyclo[3.1.1]heptane-2,3-diol (1R,2R,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-2,3-diol (1R-(1alpha,2beta,3beta,5alpha))-2,6,6-Trimethylbicyclo[3.3.1]heptane-2,3-diol [1R-(1ALPHA,2ALPHA,3ALPHA,5ALPHA)]-2,6,6-TRIMETHYLBICYCLO[3.1.1]HEPTANE-2,3-DIOL ((1R-(1ALPHA,2BETA,3BETA,5ALPHA))-2,6,6-TRIMETHYLBICYCLO(3.3.1)HEPTANE-2,3-DIOL) (-)-2-Hydroxyisopinocampheol, [1R-(1α,2α,3α,5α)]-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol
CAS	22422-34-0
InChI	InChI=1/C10H18O2/c1-9(2)6-4-7(9)10(3,12)8(11)5-6/h6-8,11-12H,4-5H2,1-3H3/t6-,7-,8-,10+/m0/s1

(1R,2R,3S,5R)-(-)-Pinanediol - Physico-chemical Properties

Molecular Formula	C10H18O2
Molar Mass	170.25
Density	0.9409 (rough estimate)
Melting Point	57-59°C(lit.)
Boling Point	101-102°C1mm Hg(lit.)
Specific Rotation(α)	-8.5 º (c=6.5, toluene)
Flash Point	>230°F
Solubility	Chloroform, Methanol, Toluene
Vapor Presure	0.001mmHg at 25°C
Appearance	White crystal
Color	Clear colorless to very faint yellow
BRN	2039144
pKa	14.68±0.60(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.4494 (estimate)
MDL	MFCD09955216
Physical and Chemical Properties	alpha:-8.5 o (c=6.5, toluene)

(1R,2R,3S,5R)-(-)-Pinanediol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
FLUKA BRAND F CODES	10
HS Code	29061990

(1R,2R,3S,5R)-(-)-Pinanediol - Introduction

(1R,2R,3S,5R)-(-)-2,3-pinanediol is a chiral organic compound with the chemical formula C10H18O2. It is a solid substance with a colorless to yellowish crystalline nature.

Regarding its properties,(1R,2R,3S,5R)-(-)-2,3-pinanediol is a stereoisomer with four chiral centers. Its optical rotation is negative. Further, it has a melting point of 80 to 82°C and a boiling point of 260°C (under reduced pressure).

This compound has a wide range of applications in the biological field. It is an important raw material for the synthesis of pesticides, pharmaceutical intermediates and antioxidants. In cosmetics and personal care products,(1R,2R,3S,5R)-(-)-2,3-pinanediol is commonly used as a stabilizer and moisturizer.
The preparation method of
(1R,2R,3S,5R)-(-)-2,3-pinanediol is mainly achieved by chemical synthesis. A common method is the reaction of pinanone with hydrogen cyanide, followed by reduction to give (1R,2R,3S,5R)-(-)-2,3-pinanediol.

With regard to safety information, the compound has not been found to be significantly toxic or dangerous. However, as any chemical, it should be used in accordance with the relevant safety procedures, and care should be taken to avoid contact with skin, eyes and respiratory system.

Last Update：2024-04-09 21:54:55