(1R,4bS,6aS,8R,10aR,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one
SHIONONE
CAS: 10376-48-4
Molecular Formula: C30H50O
(1R,4bS,6aS,8R,10aR,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one - Names and Identifiers
| Name | SHIONONE |
| Synonyms | SHIONONE 21-Shionen-3-one 2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a- hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)- 3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one (1R,4bS,6aS,8R,10aR,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one |
| CAS | 10376-48-4 |
| InChI | InChI=1/C30H50O/c1-21(2)10-9-14-26(4)16-19-30(8)25-13-15-28(6)22(3)23(31)11-12-24(28)29(25,7)18-17-27(30,5)20-26/h10,22,24-25H,9,11-20H2,1-8H3/t22-,24+,25-,26+,27-,28+,29-,30+/m0/s1 |
(1R,4bS,6aS,8R,10aR,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one - Physico-chemical Properties
| Molecular Formula | C30H50O |
| Molar Mass | 426.72 |
| Density | 0.941±0.06 g/cm3(Predicted) |
| Melting Point | 161-162° |
| Boling Point | 485.6±14.0 °C(Predicted) |
| Specific Rotation(α) | D26.5 -56.1° (c = 1.07 in chloroform) |
| Solubility | Soluble in petroleum ether, chloroform, ethyl acetate and other organic solvents, insoluble in water. |
| Appearance | White powder |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.497 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the violet. |
(1R,4bS,6aS,8R,10aR,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29143990 |
(1R,4bS,6aS,8R,10aR,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-en-1-yl)hexadecahydrochrysen-2(1H)-one - Reference Information
| pharmacological activity | visterone is extracted from the root and rhizome of Aster tataricus L.f., a common Compositae plant. Traditional medicine believes that it is warm in nature, bitter and pungent in taste, moistens the lungs and qi, and has the effect of eliminating phlegm and relieving cough. It is often used to treat the symptoms of excessive phlegm, cough, cough and hemoptysis. |
| biological activity | Shionone isolated from Aster tataricus is a triterpenoid compound with antitussive and anti-inflammatory activities. The Shionone has a unique six-membered four-ring skeleton and a 3-oxo-4-monomethyl structure. |
| Animal Model: | ICR male mice |
| Dosage: | 80 mg/kg |
| Administration: | Orally administration; 3 days; once daily |
| Result: | Reduced the ear edema for 11.3% by use shionone. |
| Use | Asterone has antitussive and expectorant effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: moisten the lungs and lower qi, eliminate phlegm and relieve cough. |
Last Update：2024-04-09 21:11:58
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Wechat: 15671228036
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Product Name: shionone Visit Supplier Webpage Request for quotationCAS: 10376-48-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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