(1S)-1-Amino-2-methyl-1-phenylpropan-2-ol - Names and Identifiers
(1S)-1-Amino-2-methyl-1-phenylpropan-2-ol - Physico-chemical Properties
Molecular Formula | C10H15NO
|
Molar Mass | 165.23 |
Density | 1.050 |
Melting Point | 47-50℃ |
Boling Point | 295.0±20.0 °C(Predicted) |
pKa | 12.65±0.50(Predicted) |
(1S)-1-Amino-2-methyl-1-phenylpropan-2-ol - Introduction
(1S)-1-Amino-2-methyl-1-phenyl-2-propanol, also known as phenylisoaminopropanol, is a chiral organic compound. Its chemical formula is C10H15NO and its molecular weight is 165.23g/mol.
Nature:
-Appearance: colorless or yellowish liquid.
-Solubility: Soluble in alcohol and ether, slightly soluble in water.
-Melting point: about 25-32 ℃.
-Boiling point: about 245-248 ℃.
-Flash point: about 113 ℃.
Use:
Phenyl isoaminopropanol is widely used in the pharmaceutical field, and its uses include but are not limited:
-As a chiral synthesis intermediate, used for the preparation of chiral drugs or their precursors.
-Chiral skeleton for synthesis, modification and improvement of drugs, natural products, chemical synthesis intermediates.
-Used as a protecting group and an activating reagent.
Preparation Method:
There are many methods for the preparation of benzene isoaminopropanol, the common ones include:
-light method: the reaction of benzene isomethylene alcohol with ammonia under light conditions.
-High selective hydrogenation method: the benzylidene aldehyde and ammonia are hydrogenated in the presence of a catalyst.
Safety Information:
Phenyl isoaminopropanol is irritating and irritating to the eyes, skin and respiratory tract. In the use and operation, should follow the correct laboratory practice. Wear chemical protective gloves, goggles and protective clothing if necessary. In case of contact with this substance, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 15:17:50