(1S,2S)-2-(Boc-amino)cyclopentanol

(1S,2S)-2-(Boc-amino)cyclopentanol - Names and Identifiers

Name	(1S,2S)-trans-N-Boc-2-aminocyclopentanol
Synonyms	(1S,2S)-2-(Boc-amino)cyclopentanol tert-butyl (1S,2S)-2-hydroxycyclopentyl (1S,2S)-trans-N-Boc-2-aminocyclopentanol tert-butyl (1S,2S)-2-hydroxycyclopentylcarbamate tert-Butyl N-((2S,1S)-2-hydroxycyclopentyl)carbamate ((1S,2S)-2-Hydroxycyclopentyl)carbamic acid tert-butyl ester Carbamic acid,N-[(1S,2S)-2-hydroxycyclopentyl]-, 1,1-dimethylethyl ester
CAS	145106-43-0

(1S,2S)-2-(Boc-amino)cyclopentanol - Physico-chemical Properties

Molecular Formula	C10H19NO3
Molar Mass	201.26
Density	1.08±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point	87.0℃
Boling Point	320.8±31.0 °C(Predicted)
BRN	5810036
pKa	12.09±0.40(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Physical and Chemical Properties	Storage Conditions: 2-8 ℃

(1S,2S)-2-(Boc-amino)cyclopentanol - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R50 - Very Toxic to aquatic organisms
Safety Description	61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs	UN 3077 9/PG 3
WGK Germany	3

(1S,2S)-2-(Boc-amino)cyclopentanol - Introduction

(1S,2S)-trans-N-Boc-2-aminocyclopentanol, also known as Boc-D-cyclopentylalaninol, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
(1S,2S)-The chemical formula of trans-N-Boc-2-aminocyclopentanol is C12H21NO3 and the molecular weight is 227.3. It is a white solid, soluble in organic solvents such as ether and methylene chloride, and insoluble in water. It is a chiral molecule and has two chiral centers, so there are four optical isomers.

Use:
It is often used as an intermediate in organic synthesis to build more complex organic molecules. It can be used for the synthesis of polypeptides, proteins, drugs, etc. In addition, it can also be used in the field of asymmetric synthesis and drug research.

Method:
(1S,2S)-There are many ways to prepare trans-N-Boc-2-aminocyclopentanol. A common method is to react cyclopentanone with the corresponding amino acid ester to obtain the corresponding alcohol, which is then reduced by reaction (e. G., acetylene reduction, ketone reduction) or hydrogenation agent (e. G: alcoholation method) to remove the carbonyl group, and finally through the protection group reaction to obtain the target product.

Safety Information:
The safety information about (1S,2S)-trans-N-Boc-2-aminocyclopentanol is rarely reported, but general organic compounds need to be operated under appropriate experimental conditions. It may be irritating to the skin, eyes and respiratory system, so wear appropriate protective equipment when using it. In addition, it may also have certain potential hazards to the environment, so caution is needed when handling and disposing of waste. Before use, it is best to carry out adequate risk assessment and appropriate control measures. It is recommended to refer to the safety technical specifications and relevant chemical management regulations.

Last Update：2024-04-09 21:32:37