(1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine

(1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine - Names and Identifiers

Name	(1S,2S)-(+)-N,N-Dimethylcyclohexane-1,2-diamine
Synonyms	N,N'-Dimethyl-1S,2S-Diaminocyclohexane (1S,2S)-(+)-N,N-Dimethyl diaminocyclohexane (1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine 1R,2R-(-)-OR1S,2S-(+)-N,N-DIAMINOCYCLOHEXANE (1S,2S)-N1,N1-Dimethyl-1,2-cyclohexanediamine (1S,2S)-N1,N1-Dimethylcyclohexane-1,2-diamine (1S,2S)-1-N,1-N-diMethylcyclohexane-1,2-diaMine (1S,2S)-(+)-N,N-Dimethylcyclohexane-1,2-diamine
CAS	894493-95-9
InChI	InChI=1/C8H18N2/c1-10(2)8-6-4-3-5-7(8)9/h7-8H,3-6,9H2,1-2H3/t7-,8-/m0/s1

(1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine - Physico-chemical Properties

Molecular Formula	C8H18N2
Molar Mass	142.24
Density	0.92
Boling Point	180 °C
Flash Point	62 °C
pKa	10.52±0.70(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.49

(1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2735
HS Code	29130000
Hazard Class	8
Packing Group	Ⅲ

(1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine - Introduction

(1S,2S)-( )-N,N-Dimethylcyclohexane-1,2-diamine is a chiral compound with the formula C8H18N2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
(1S,2S)-( )-N,N-Dimethylcyclohexane-1,2-diamine is a colorless liquid with the characteristic ammonia odor of amines. It is flammable at room temperature and soluble in a variety of organic solvents such as water and ethanol.

Use:
(1S,2S)-( )-N,N-Dimethylcyclohexane-1,2-diamine is a chiral reagent commonly used in organic synthesis, which can be used to catalyze asymmetric reactions. It has a wide range of applications in the field of synthetic drugs, pesticides, spices and polymer compounds.

Preparation Method:
A common method for preparing (1S,2S)-( )-N,N-Dimethylcyclohexane-1,2-diamine is to use chiral ligands to control the metal-catalyzed reaction. Common ligands include diphosphonium and cephalosporins. The configuration of the two chiral carbon atoms is derived from the ligand.

Safety Information:
(1S,2S)-( )-N,N-Dimethylcyclohexane-1,2-diamine is mildly irritating and should avoid contact with skin and eyes. It may also affect the central nervous system of the human body, so care should be taken to use protective gloves, goggles and ventilation equipment during operation. During storage and handling, please follow the safety procedures for chemicals to avoid contact with oxidants and acids. If inhaled or taken by mistake, please seek medical treatment in time.

Last Update：2024-04-09 20:49:11