(1S,2S)-反式-2-氨基环戊醇

(1S,2S)-反式-2-氨基环戊醇 - Names and Identifiers

Name	Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride
Synonyms	(1s,2s)-2-aminocyclopentan-1-ol trans-(1S,2S)-2-Aminocyclopentanol HCL (1S,2S)-trans-2-AMinocyclopentanol HCl TRANS-(1S 2S)-2-AMINOCYCLOPENTANOL HYDRO (1S,2S)-2-Aminocyclopentanolhydrochlorid (1S,2S)-2-aminocyclopentanol chlorhydrate (1S,2S)-2-aMinocyclopentanol hydrochloride (1S,2S)-2-aminocyclopentanol hydrochloride (1S,2S)-2-aMinocyclopentan-1-ol hydrochloride (1S,2S)-Trans-2-Aminocyclopentanol Hydrochloride (1s,2s)-trans-2-aminocyclopentanol hydrochloride Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride
CAS	68327-04-8
InChI	InChI=1/C5H11NO.ClH/c6-4-2-1-3-5(4)7;/h4-5,7H,1-3,6H2;1H/t4-,5-;/m0./s1

(1S,2S)-反式-2-氨基环戊醇 - Physico-chemical Properties

Molecular Formula	C5H12ClNO
Molar Mass	137.61
Boling Point	220.9°C at 760 mmHg
Flash Point	87.4°C
Vapor Presure	0.0229mmHg at 25°C
Appearance	crystal
Color	white
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Easily absorbing moisture
MDL	MFCD07370092

(1S,2S)-反式-2-氨基环戊醇 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves.
WGK Germany	2
FLUKA BRAND F CODES	10-21
TSCA	No

(1S,2S)-反式-2-氨基环戊醇 - Introduction

Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride is an organic compound with the chemical formula C5H12ClNO. Its properties are as follows:

Appearance: White crystalline solid
Melting point: 155-160 degrees Celsius
Solubility: Soluble in water and alcohol, slightly soluble in non-polar solvents

Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride are commonly used as reagents and intermediates in organic synthesis, and have many applications:

1. Synthesis of chiral heterocyclic compounds: It can be used as a chiral inducer for the synthesis of chiral heterocyclic compounds.
2. Drug synthesis: It is often used in the preparation of enantiomerically pure organic molecules in drug synthesis.
3. Biological activity research: It can be used to synthesize compounds with biological activity, such as drugs or fluorescent probes.

The method for preparing Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride generally includes the following steps:

1. cyclopentene reacts with nitroso hydrochloric acid to obtain cyclopentanal nitroso hydrochloric acid ester.
2. Cyclopentanal nitroso hydrochloride can be reacted with ammonia to obtain trans-(1S,2S)-2-amino-cyclopentanal by denitrogenation.
3. Trans-(1S,2S)-2-amino-cyclopentanal is reacted with hydrochloric acid to generate Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride.

When using Trans-(1S,2S)-2-Amino-Cyclopentanol Hydrochloride, pay attention to the following safety information:

1. avoid contact with skin and eyes, do not breathe dust or gas.
2. Pay attention to good ventilation conditions during operation.
3. Use personal protective equipment such as lab gloves and goggles.
4. storage should be sealed, away from the fire and oxidant.
5. if inhalation or contact, should immediately seek medical treatment.

The above information is for reference only. Please refer to the relevant laboratory operation guide and safety manual for specific operation.

Last Update：2024-04-09 15:17:59